ID   F3AIU8_9FIRM            Unreviewed;       360 AA.
AC   F3AIU8;
DT   28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT   28-JUN-2011, sequence version 1.
DT   27-MAR-2024, entry version 47.
DE   RecName: Full=Signal transduction histidine kinase subgroup 3 dimerisation and phosphoacceptor domain-containing protein {ECO:0000259|Pfam:PF07730};
GN   ORFNames=HMPREF0987_00401 {ECO:0000313|EMBL:EGG88176.1};
OS   Lachnospiraceae bacterium 9_1_43BFAA.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX   NCBI_TaxID=658088 {ECO:0000313|EMBL:EGG88176.1, ECO:0000313|Proteomes:UP000003620};
RN   [1] {ECO:0000313|EMBL:EGG88176.1, ECO:0000313|Proteomes:UP000003620}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=9_1_43BFAA {ECO:0000313|EMBL:EGG88176.1,
RC   ECO:0000313|Proteomes:UP000003620};
RG   The Broad Institute Genome Sequencing Platform;
RA   Earl A., Ward D., Feldgarden M., Gevers D., Daigneault M., Strauss J.,
RA   Ambrose C., Allen-Vercoe E., Young S.K., Zeng Q., Gargeya S.,
RA   Fitzgerald M., Haas B., Abouelleil A., Alvarado L., Arachchi H.M.,
RA   Berlin A., Brown A., Chapman S.B., Chen Z., Dunbar C., Freedman E.,
RA   Gearin G., Gellesch M., Goldberg J., Griggs A., Gujja S., Heilman E.R.,
RA   Heiman D., Howarth C., Larson L., Lui A., MacDonald P.J.P., Mehta T.,
RA   Montmayeur A., Murphy C., Neiman D., Pearson M., Priest M., Roberts A.,
RA   Saif S., Shea T., Shenoy N., Sisk P., Stolte C., Sykes S., White J.,
RA   Yandava C., Wortman J., Nusbaum C., Birren B.;
RT   "The Genome Sequence of Lachnospiraceae bacterium 9_1_43BFAA.";
RL   Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EGG88176.1}.
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DR   EMBL; ACTX01000002; EGG88176.1; -; Genomic_DNA.
DR   AlphaFoldDB; F3AIU8; -.
DR   eggNOG; COG4585; Bacteria.
DR   HOGENOM; CLU_000445_20_3_9; -.
DR   Proteomes; UP000003620; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR   GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR   CDD; cd16917; HATPase_UhpB-NarQ-NarX-like; 1.
DR   Gene3D; 1.20.5.1930; -; 1.
DR   Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR   InterPro; IPR036890; HATPase_C_sf.
DR   InterPro; IPR011712; Sig_transdc_His_kin_sub3_dim/P.
DR   PANTHER; PTHR24421; NITRATE/NITRITE SENSOR PROTEIN NARX-RELATED; 1.
DR   PANTHER; PTHR24421:SF64; TWO-COMPONENT SENSOR HISTIDINE KINASE; 1.
DR   Pfam; PF07730; HisKA_3; 1.
DR   SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
PE   4: Predicted;
KW   Kinase {ECO:0000256|ARBA:ARBA00022777}; Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000003620};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius};
KW   Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT   TRANSMEM        47..71
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        78..99
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          169..231
FT                   /note="Signal transduction histidine kinase subgroup 3
FT                   dimerisation and phosphoacceptor"
FT                   /evidence="ECO:0000259|Pfam:PF07730"
SQ   SEQUENCE   360 AA;  41151 MW;  C6B88B72085D6C8D CRC64;
     MRQFLNKSFL ILYSLLLLCP TNTDRSFVVG FFLAVFTAMT TFFFTSRRYA CSVLPIFLVA
     APFYPALFLF FPVICYDLCL YRILPLFFLV VADFLFLITS SATDQILYIL FGCITAILLE
     KHTSDYDQLK EHYIHTIDDQ TEKNMLLSQK HEALLQKQDS EIYTATLQER NRIAREIHDN
     VGHMLSRAIL LSGAIRTINK EESLQEPLRQ LTDTLSLAMD NIRTSVHDLH DDSVNLKEVT
     EELTSSFTFC PITLEYDMPI TVPRTIKYAF LSITKEALSN IIKHSNATAV SILMREHPAL
     WQLVIQDNGT LQSPSATEGI GLENMKERIR KLNGTITFSC ENGFSIFIAI PKNKKEESDL
//