ID F3AJM2_9FIRM Unreviewed; 441 AA.
AC F3AJM2;
DT 28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT 28-JUN-2011, sequence version 1.
DT 24-JAN-2024, entry version 37.
DE RecName: Full=Branched-chain amino acid transport system carrier protein {ECO:0000256|RuleBase:RU362122};
GN ORFNames=HMPREF0987_00646 {ECO:0000313|EMBL:EGG87530.1};
OS Lachnospiraceae bacterium 9_1_43BFAA.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX NCBI_TaxID=658088 {ECO:0000313|EMBL:EGG87530.1, ECO:0000313|Proteomes:UP000003620};
RN [1] {ECO:0000313|EMBL:EGG87530.1, ECO:0000313|Proteomes:UP000003620}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=9_1_43BFAA {ECO:0000313|EMBL:EGG87530.1,
RC ECO:0000313|Proteomes:UP000003620};
RG The Broad Institute Genome Sequencing Platform;
RA Earl A., Ward D., Feldgarden M., Gevers D., Daigneault M., Strauss J.,
RA Ambrose C., Allen-Vercoe E., Young S.K., Zeng Q., Gargeya S.,
RA Fitzgerald M., Haas B., Abouelleil A., Alvarado L., Arachchi H.M.,
RA Berlin A., Brown A., Chapman S.B., Chen Z., Dunbar C., Freedman E.,
RA Gearin G., Gellesch M., Goldberg J., Griggs A., Gujja S., Heilman E.R.,
RA Heiman D., Howarth C., Larson L., Lui A., MacDonald P.J.P., Mehta T.,
RA Montmayeur A., Murphy C., Neiman D., Pearson M., Priest M., Roberts A.,
RA Saif S., Shea T., Shenoy N., Sisk P., Stolte C., Sykes S., White J.,
RA Yandava C., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Lachnospiraceae bacterium 9_1_43BFAA.";
RL Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Component of the transport system for branched-chain amino
CC acids. {ECO:0000256|RuleBase:RU362122}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU362122};
CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU362122}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the branched chain amino acid transporter
CC family. {ECO:0000256|ARBA:ARBA00008540, ECO:0000256|RuleBase:RU362122}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EGG87530.1}.
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DR EMBL; ACTX01000003; EGG87530.1; -; Genomic_DNA.
DR AlphaFoldDB; F3AJM2; -.
DR eggNOG; COG1114; Bacteria.
DR HOGENOM; CLU_036807_0_1_9; -.
DR Proteomes; UP000003620; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015658; F:branched-chain amino acid transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR InterPro; IPR004685; Brnchd-chn_aa_trnsp_Livcs.
DR NCBIfam; TIGR00796; livcs; 1.
DR PANTHER; PTHR30588; BRANCHED-CHAIN AMINO ACID TRANSPORT SYSTEM 2 CARRIER PROTEIN; 1.
DR PANTHER; PTHR30588:SF0; BRANCHED-CHAIN AMINO ACID TRANSPORT SYSTEM 2 CARRIER PROTEIN; 1.
DR Pfam; PF05525; Branch_AA_trans; 1.
PE 3: Inferred from homology;
KW Amino-acid transport {ECO:0000256|ARBA:ARBA00022970,
KW ECO:0000256|RuleBase:RU362122};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU362122};
KW Reference proteome {ECO:0000313|Proteomes:UP000003620};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU362122};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU362122};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU362122}.
FT TRANSMEM 12..32
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362122"
FT TRANSMEM 44..67
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362122"
FT TRANSMEM 79..98
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362122"
FT TRANSMEM 118..137
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362122"
FT TRANSMEM 144..166
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362122"
FT TRANSMEM 207..225
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362122"
FT TRANSMEM 237..258
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362122"
FT TRANSMEM 278..310
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362122"
FT TRANSMEM 322..342
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362122"
FT TRANSMEM 348..365
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362122"
FT TRANSMEM 374..392
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362122"
FT TRANSMEM 412..434
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362122"
SQ SEQUENCE 441 AA; 47943 MW; 8C760C0C4CA3BE44 CRC64;
MEKLNLKQIS SLTLTLFAIF FGAGNMIFPP AMGQLAGENY LQALAGFILT DAGIALLGIV
AVVLLGNRIT DLGNLVSRRF SLCLSVTVYL LIGPLFALPR TGSVSYELAI RPYIPQEYVW
LVSLLVTAVF FSLTYYFSGN PKKIVDIIGQ YMTPILILSI TVLYFVCLFA DKSGNVIQYG
AVQSTGEYQD IAFFKGMIEG YNALDGPAGP VFAIIIINAV TGFGVRERKS IVKYTIFSGM
GAVLILSGIY YMLAYIGATT QTVFANGGAL LHAVASDLIG PAGGIVLGMS VFLACMTTAI
GLTTSFANYF HELIPQLSYR RITAIVCLFS FAVSNVGLSY MITISQPVLM MIYPVLIVLI
VLSFGHKWIG RRKMVYIFSM AVAFGIAFIN AMEGVGIELG MLTEWAKKLP LYELHLGWML
PAAGGALLGL LPFWKKKKIE N
//
