ID   F3AKM4_9FIRM            Unreviewed;       761 AA.
AC   F3AKM4;
DT   28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT   28-JUN-2011, sequence version 1.
DT   24-JAN-2024, entry version 38.
DE   SubName: Full=Anaerobic ribonucleoside-triphosphate reductase {ECO:0000313|EMBL:EGG87000.1};
GN   ORFNames=HMPREF0987_00998 {ECO:0000313|EMBL:EGG87000.1};
OS   Lachnospiraceae bacterium 9_1_43BFAA.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX   NCBI_TaxID=658088 {ECO:0000313|EMBL:EGG87000.1, ECO:0000313|Proteomes:UP000003620};
RN   [1] {ECO:0000313|EMBL:EGG87000.1, ECO:0000313|Proteomes:UP000003620}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=9_1_43BFAA {ECO:0000313|EMBL:EGG87000.1,
RC   ECO:0000313|Proteomes:UP000003620};
RG   The Broad Institute Genome Sequencing Platform;
RA   Earl A., Ward D., Feldgarden M., Gevers D., Daigneault M., Strauss J.,
RA   Ambrose C., Allen-Vercoe E., Young S.K., Zeng Q., Gargeya S.,
RA   Fitzgerald M., Haas B., Abouelleil A., Alvarado L., Arachchi H.M.,
RA   Berlin A., Brown A., Chapman S.B., Chen Z., Dunbar C., Freedman E.,
RA   Gearin G., Gellesch M., Goldberg J., Griggs A., Gujja S., Heilman E.R.,
RA   Heiman D., Howarth C., Larson L., Lui A., MacDonald P.J.P., Mehta T.,
RA   Montmayeur A., Murphy C., Neiman D., Pearson M., Priest M., Roberts A.,
RA   Saif S., Shea T., Shenoy N., Sisk P., Stolte C., Sykes S., White J.,
RA   Yandava C., Wortman J., Nusbaum C., Birren B.;
RT   "The Genome Sequence of Lachnospiraceae bacterium 9_1_43BFAA.";
RL   Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EGG87000.1}.
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DR   EMBL; ACTX01000005; EGG87000.1; -; Genomic_DNA.
DR   AlphaFoldDB; F3AKM4; -.
DR   eggNOG; COG1328; Bacteria.
DR   HOGENOM; CLU_002707_2_1_9; -.
DR   Proteomes; UP000003620; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0008998; F:ribonucleoside-triphosphate reductase activity; IEA:InterPro.
DR   GO; GO:0006260; P:DNA replication; IEA:InterPro.
DR   CDD; cd01675; RNR_III; 1.
DR   Gene3D; 3.20.70.20; -; 1.
DR   InterPro; IPR005144; ATP-cone_dom.
DR   InterPro; IPR012833; NrdD.
DR   NCBIfam; TIGR02487; NrdD; 1.
DR   PANTHER; PTHR21075; ANAEROBIC RIBONUCLEOSIDE-TRIPHOSPHATE REDUCTASE; 1.
DR   PANTHER; PTHR21075:SF0; ANAEROBIC RIBONUCLEOSIDE-TRIPHOSPHATE REDUCTASE; 1.
DR   Pfam; PF03477; ATP-cone; 1.
DR   Pfam; PF13597; NRDD; 1.
DR   SUPFAM; SSF51998; PFL-like glycyl radical enzymes; 1.
DR   PROSITE; PS51161; ATP_CONE; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW   ProRule:PRU00492}; Coiled coil {ECO:0000256|SAM:Coils};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW   ProRule:PRU00492}; Reference proteome {ECO:0000313|Proteomes:UP000003620}.
FT   DOMAIN          3..95
FT                   /note="ATP-cone"
FT                   /evidence="ECO:0000259|PROSITE:PS51161"
FT   COILED          244..288
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   761 AA;  86046 MW;  DE1F3F1466182C2C CRC64;
     MIRSIIKRDG RVVLYDESKI ASAILKAMEA AGEGDATDAA NVANDVQSKL EKLPEDMPPQ
     IEQVQDTVER ALMKKGFEES AKKFILYRAQ RTHIREANTS LMKTIDEITN IDARESDMKR
     DNANIDGNTS MGSMLQIGAA GAKNYNEAYL LTPEQAKAYR EGDIHIHDFD FYSLTTTCTQ
     IDIEKLFQGG FSTGHGVIRE PQCIQSYAAL AAIAIQSNQN DQHGGQSIPN FDYGLAKGVA
     KSFQKIYKKQ LTEAVEDLAD LEDEEVQITQ MLDELKQTKE LFPRLKQEEE VFDRAVQQKL
     CERYHFTEEK ATHITEKVRK RTEKYTERDT YQAMEGFVHN LNTMHSRAGA QTPFSSINYG
     TDISPEGRMI IRNVLLATDA GLGNGETCIF PIHIFKVKEG VNYNEGDPNY DLFRLSCKVS
     AKRLFPNFVF LDSPFNLQYY KPGHPETEVA TMGCRTRVMG NVYDPEHEIA YSRGNLSFTS
     INLPRLAIES KGDEKVFYQK LDAMLELVAR QLMDRFEIQA KKCVYNYPFL MGQGVWLDSE
     KLGPNEEVRE VLKHGTLSIG YIGLAETLTA LYGKHHGESE EMQQKGLEII GHMRAFTDAK
     AKETKMNYTL LATPAEGLSG RFLRMDQKRY GKIPGVTDRE YYTNSFHIPV WYPISAYEKI
     RKEAPYHALS NGGHISYVEL DGDTAKNVEA FESVIRCMHD AGIGYGSVNH PVDRDPACGY
     VGVIDDVCPR CGRREGEPIS DEKLKELRKL YPEMPQFCGC R
//