ID   F3APC5_9FIRM            Unreviewed;       259 AA.
AC   F3APC5;
DT   28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT   28-JUN-2011, sequence version 1.
DT   24-JAN-2024, entry version 45.
DE   RecName: Full=Thymidylate synthase {ECO:0008006|Google:ProtNLM};
GN   ORFNames=HMPREF0987_02299 {ECO:0000313|EMBL:EGG89520.1};
OS   Lachnospiraceae bacterium 9_1_43BFAA.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX   NCBI_TaxID=658088 {ECO:0000313|EMBL:EGG89520.1, ECO:0000313|Proteomes:UP000003620};
RN   [1] {ECO:0000313|EMBL:EGG89520.1, ECO:0000313|Proteomes:UP000003620}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=9_1_43BFAA {ECO:0000313|EMBL:EGG89520.1,
RC   ECO:0000313|Proteomes:UP000003620};
RG   The Broad Institute Genome Sequencing Platform;
RA   Earl A., Ward D., Feldgarden M., Gevers D., Daigneault M., Strauss J.,
RA   Ambrose C., Allen-Vercoe E., Young S.K., Zeng Q., Gargeya S.,
RA   Fitzgerald M., Haas B., Abouelleil A., Alvarado L., Arachchi H.M.,
RA   Berlin A., Brown A., Chapman S.B., Chen Z., Dunbar C., Freedman E.,
RA   Gearin G., Gellesch M., Goldberg J., Griggs A., Gujja S., Heilman E.R.,
RA   Heiman D., Howarth C., Larson L., Lui A., MacDonald P.J.P., Mehta T.,
RA   Montmayeur A., Murphy C., Neiman D., Pearson M., Priest M., Roberts A.,
RA   Saif S., Shea T., Shenoy N., Sisk P., Stolte C., Sykes S., White J.,
RA   Yandava C., Wortman J., Nusbaum C., Birren B.;
RT   "The Genome Sequence of Lachnospiraceae bacterium 9_1_43BFAA.";
RL   Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EGG89520.1}.
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DR   EMBL; ACTX01000012; EGG89520.1; -; Genomic_DNA.
DR   AlphaFoldDB; F3APC5; -.
DR   eggNOG; COG1351; Bacteria.
DR   HOGENOM; CLU_1178602_0_0_9; -.
DR   Proteomes; UP000003620; Unassembled WGS sequence.
DR   GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR   GO; GO:0050797; F:thymidylate synthase (FAD) activity; IEA:UniProtKB-EC.
DR   GO; GO:0006231; P:dTMP biosynthetic process; IEA:InterPro.
DR   CDD; cd20175; ThyX; 1.
DR   Gene3D; 3.30.1360.170; -; 1.
DR   InterPro; IPR003669; Thymidylate_synthase_ThyX.
DR   InterPro; IPR036098; Thymidylate_synthase_ThyX_sf.
DR   PANTHER; PTHR34934; FLAVIN-DEPENDENT THYMIDYLATE SYNTHASE; 1.
DR   PANTHER; PTHR34934:SF1; FLAVIN-DEPENDENT THYMIDYLATE SYNTHASE; 1.
DR   Pfam; PF02511; Thy1; 1.
DR   SUPFAM; SSF69796; Thymidylate synthase-complementing protein Thy1; 1.
DR   PROSITE; PS51331; THYX; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000003620}.
SQ   SEQUENCE   259 AA;  29530 MW;  A782D06232C031D4 CRC64;
     MDHIETAILN CYGIREAEQN MVFAARLTQH GHTIQNMADL MDLYHQSYSQ KTVENIAGLP
     HPTVQKFMVI TVAVVGASRR FLAQITRHQN EVKYMSASLQ YSNYSGHAAF AIPYGIMKAD
     KEIQDIYKKS CQSDLDHYAE LCALGIDHDS AGYATPQGLR NVLIISATPY QWKHMIGQRT
     CRRNTDETRI VMLQIWQRLY KLSPILFAPD LTGPFCQRGS CMEKQMSCKD PISKIWTPAD
     ILKEDYPLLI QKEVSSHKD
//