ID F3B9V6_9FIRM Unreviewed; 309 AA.
AC F3B9V6;
DT 28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT 28-JUN-2011, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE RecName: Full=SIS domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=HMPREF9477_00726 {ECO:0000313|EMBL:EGG84228.1};
OS Lachnospiraceae bacterium 2_1_46FAA.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX NCBI_TaxID=742723 {ECO:0000313|EMBL:EGG84228.1, ECO:0000313|Proteomes:UP000018451};
RN [1] {ECO:0000313|EMBL:EGG84228.1, ECO:0000313|Proteomes:UP000018451}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=2_1_46FAA {ECO:0000313|EMBL:EGG84228.1,
RC ECO:0000313|Proteomes:UP000018451};
RG The Broad Institute Genome Sequencing Platform;
RA Earl A., Ward D., Feldgarden M., Gevers D., Daigneault M., Strauss J.,
RA Ambrose C., Allen-Vercoe E., Walker B., Young S.K., Zeng Q., Gargeya S.,
RA Fitzgerald M., Haas B., Abouelleil A., Alvarado L., Arachchi H.M.,
RA Berlin A.M., Chapman S.B., Dewar J., Goldberg J., Griggs A., Gujja S.,
RA Hansen M., Howarth C., Imamovic A., Larimer J., McCowan C., Murphy C.,
RA Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T., Sisk P.,
RA Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Lachnospiraceae bacterium 2_1_46FAA.";
RL Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EGG84228.1}.
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DR EMBL; ADLB02000007; EGG84228.1; -; Genomic_DNA.
DR AlphaFoldDB; F3B9V6; -.
DR STRING; 742723.HMPREF9477_00726; -.
DR eggNOG; COG1737; Bacteria.
DR HOGENOM; CLU_055769_1_1_9; -.
DR OrthoDB; 2930at2; -.
DR Proteomes; UP000018451; Unassembled WGS sequence.
DR GO; GO:0097367; F:carbohydrate derivative binding; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:1901135; P:carbohydrate derivative metabolic process; IEA:InterPro.
DR CDD; cd05013; SIS_RpiR; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR000281; HTH_RpiR.
DR InterPro; IPR047640; RpiR-like.
DR InterPro; IPR035472; RpiR-like_SIS.
DR InterPro; IPR001347; SIS_dom.
DR InterPro; IPR046348; SIS_dom_sf.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR30514; GLUCOKINASE; 1.
DR PANTHER; PTHR30514:SF18; RPIR-FAMILY TRANSCRIPTIONAL REGULATOR; 1.
DR Pfam; PF01418; HTH_6; 1.
DR Pfam; PF01380; SIS; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR SUPFAM; SSF53697; SIS domain; 1.
DR PROSITE; PS51071; HTH_RPIR; 1.
DR PROSITE; PS51464; SIS; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000018451}.
FT DOMAIN 7..83
FT /note="HTH rpiR-type"
FT /evidence="ECO:0000259|PROSITE:PS51071"
FT DOMAIN 129..275
FT /note="SIS"
FT /evidence="ECO:0000259|PROSITE:PS51464"
SQ SEQUENCE 309 AA; 34435 MW; 3CF1BFF0484EA627 CRC64;
MNSNNTNELL SKINEKYARL SKGQKLLAEY IAENYDKAVF LTAAKLGKTV GVSESTVVRF
ATQLGYDGYP GFQKALEELV RNKLNSIQRM EVAYGRIAQS EILETVLQSD IEKIKLTLAG
IEQGAFDLAV DTMLNAKRIY IVGIRSCAPL ASFLGFYLNL IFDNVTLVNT NSASEIFEQL
IRINEEDVII GISFPRYSMR TLKALEFASN RKAKVITLTD SVHSPMNLYS SCNLIARSDM
ASIVDSLVAP LSVVNALVVA LCMKKQTEVI DTLGTLEKIW DEYQVYSSDE LNPVNDKMSL
KKVERDGEK
//
