ID F3BAI9_9FIRM Unreviewed; 1856 AA.
AC F3BAI9;
DT 28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT 28-JUN-2011, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE RecName: Full=F5/8 type C domain-containing protein {ECO:0000259|PROSITE:PS50022};
GN ORFNames=HMPREF9477_00959 {ECO:0000313|EMBL:EGG83584.1};
OS Lachnospiraceae bacterium 2_1_46FAA.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX NCBI_TaxID=742723 {ECO:0000313|EMBL:EGG83584.1, ECO:0000313|Proteomes:UP000018451};
RN [1] {ECO:0000313|EMBL:EGG83584.1, ECO:0000313|Proteomes:UP000018451}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=2_1_46FAA {ECO:0000313|EMBL:EGG83584.1,
RC ECO:0000313|Proteomes:UP000018451};
RG The Broad Institute Genome Sequencing Platform;
RA Earl A., Ward D., Feldgarden M., Gevers D., Daigneault M., Strauss J.,
RA Ambrose C., Allen-Vercoe E., Walker B., Young S.K., Zeng Q., Gargeya S.,
RA Fitzgerald M., Haas B., Abouelleil A., Alvarado L., Arachchi H.M.,
RA Berlin A.M., Chapman S.B., Dewar J., Goldberg J., Griggs A., Gujja S.,
RA Hansen M., Howarth C., Imamovic A., Larimer J., McCowan C., Murphy C.,
RA Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T., Sisk P.,
RA Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Lachnospiraceae bacterium 2_1_46FAA.";
RL Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EGG83584.1}.
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DR EMBL; ADLB02000007; EGG83584.1; -; Genomic_DNA.
DR STRING; 742723.HMPREF9477_00959; -.
DR eggNOG; COG1538; Bacteria.
DR eggNOG; COG3525; Bacteria.
DR HOGENOM; CLU_001501_1_1_9; -.
DR OrthoDB; 9760892at2; -.
DR Proteomes; UP000018451; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016231; F:beta-N-acetylglucosaminidase activity; IEA:UniProt.
DR GO; GO:1901135; P:carbohydrate derivative metabolic process; IEA:UniProt.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:UniProt.
DR GO; GO:1901564; P:organonitrogen compound metabolic process; IEA:UniProt.
DR Gene3D; 1.20.1270.90; AF1782-like; 6.
DR Gene3D; 3.30.379.10; Chitobiase/beta-hexosaminidase domain 2-like; 1.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 3.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 2.60.40.1180; Golgi alpha-mannosidase II; 1.
DR Gene3D; 1.20.58.460; Hyaluronidase post-catalytic domain-like; 1.
DR InterPro; IPR000421; FA58C.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR013780; Glyco_hydro_b.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR029018; Hex-like_dom2.
DR InterPro; IPR015882; HEX_bac_N.
DR InterPro; IPR011496; O-GlcNAcase_cat.
DR PANTHER; PTHR13170; O-GLCNACASE; 1.
DR PANTHER; PTHR13170:SF16; PROTEIN O-GLCNACASE; 1.
DR Pfam; PF00754; F5_F8_type_C; 3.
DR Pfam; PF07554; FIVAR; 4.
DR Pfam; PF02838; Glyco_hydro_20b; 1.
DR Pfam; PF07555; NAGidase; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF55545; beta-N-acetylhexosaminidase-like domain; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 3.
DR SUPFAM; SSF140657; Hyaluronidase post-catalytic domain-like; 1.
DR PROSITE; PS50022; FA58C_3; 1.
PE 4: Predicted;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000018451};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..31
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 32..1856
FT /note="F5/8 type C domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003292372"
FT TRANSMEM 1831..1850
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 631..732
FT /note="F5/8 type C"
FT /evidence="ECO:0000259|PROSITE:PS50022"
FT REGION 1806..1825
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1856 AA; 207096 MW; 629D1DE7F1AED28F CRC64;
MKKILKRILT GTLAVAMVLT MMPISTPTVQ AAKDKTAYEI YPNPHDMSYQ DGEFVIRQEV
NVVFEKTIDS VTQKRMNEVL ASKNKKVTTS QEKVEGKTNI LVGTYNSKEY VDTYVKEHYN
VEASLFEKFG ANFVASNNGE IVVLGRDTDA AFYGITSLKH IFNQMNGSTI RNFTIKDYAD
TNIRGFIEGY YGIPWSNEDR MSLMKFGGDF KMTSYIFAPK DDPYHKEKWR EEYPAKELAE
ITEMVKVGNE AKCRFVWTAH PFMGGFNANN ADAEIQALLK KFEQLYKAGV RQFGVLGDDV
GQLNKDIVVK MMQEVSKWAK AKGDVYDTVF CPAGYNHSWQ GDYSELNKYD KEFPEDIKIF
WTGEAVCQPV EQKTLNHFRK HNLNGQATRR SPLFWLNWPV NDINGQRLMM GKGSLLHTDI
TLEDLAGVVT NPMQEAEASK VAIFAVADYA WNVKAFDDDK SWEDSFKYVD AQASEALHTL
AKHMSNPQPN GHGLVLAESE ELQPLINKIN TQLTAGKLVD ADAKQMIAEM QTIIDACKEF
HAQSKNANLK KELKPFTGSL ADLAKAIQEY VKAEMAVEAK DMFTAFNHYN TGYSALLSSK
KHERKMLNGS AMVSPGSTHL IPLAKKLQTK LSGPVNDYAT GGVGSQQVEM TATSNISGWH
QGPIGNIIDG NDKTHAWANT EEKVGQYFQV AFNKPVTVYG IHIINGANQD NKHQDTFGTA
QLKYKVQGSE EWKLVSQDTY RDYAEFVDVS QIELENVVAV RYECTEKGSG NKWPAMREFK
VSTIPENAEN FTKTVIRTSN AEGWSVSSGK ETNVVDGDLN TNVHYNVRQQ GDPVNTTIVG
DYVGVELSKP IVLGKINITQ GRDDNDGDYF TDADLEYSMD KNKWTTIKNF KNARKISVDV
SDQNITAKYV RLVNKKQQPT WIAMREFDVD AKIFHNGKVF TNVDKYKKHT ADYLADTAEV
TPIDNVTLAK NEYIGLKLDR IHELAEITSK LSDENLTVQL SKNNVEWKDI NVKESKATKV
TDDARYVRII NKTENAITFN VEKFAVKTVE IYPKSVKETN YSEIENPLNV FDGDITTATH
YKNSQTQGKF FTYDLGQEID LKTFKVVCRD SEHDFPRHAK FSVSTDGKTW EEIMTLGNQD
KDNEGEAAGS DHINTVLPTH EISYNVKKET NINKKARYLK FEITRNKSGS DKWVRFNELE
INDGEFMPSE NNPTYKSDAE ETRDGLFRNM SDGDIATMFV PSKDNGYVQY SLSDNTDVNT
IKVLQNASAI SNATVKARVW EDKKEKWVTV GKLSQSYNEF VLPNDTVLLD VKVEWDKTTP
NITELLTYKS DYKAADKNAL KALIDSKEDT TKWTTSTAKV YADAYKAGQE VMSSENVSQD
SVNNAVTAIN KAIEGKQLKG DISVLETIVK DAYKDADTYT AKTWAVYEKA INACKAAIEN
KDDTSEKDVE TLKKAVEDAK AGLVYNPTNQ EMASIAVEEA NAFIASITNP ENVYTQNSWK
AYVDAKKEVE SLLEENKTTP QHPDTFEAAL NKLTAAKENL VALGELPTLI ADFDAIKDSS
IYTKDSFDAY KTAVDNARQL LVNGTKETIA EAIKNIKTAK DNLKLSGNVD ASKVNALLNE
LKNLTAGNYT EKSFNELQKV VTEVGNKDLS ALSQEELQEC LNQLNGAKQN LVSVKALKDA
IASAGEYAAD KYTANSYKVL TDAVSDGKAL FAAGTKEEIS KATDTIYKAM KGLVVRANAD
EVKAYVESIV EKDLSKYTSE STKAYKDALA VLKNMLNDLD NVSATGFAQA KANFEKAEAG
LVVKDTTVPD KKPNKKPGNK PVKTGDAANS VMPIALMIAS MAIAGGVLVF RRKRTK
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