ID F3KSS8_9BURK Unreviewed; 1097 AA.
AC F3KSS8;
DT 28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT 28-JUN-2011, sequence version 1.
DT 24-JAN-2024, entry version 38.
DE SubName: Full=Acriflavin resistance protein {ECO:0000313|EMBL:EGI77147.1};
GN ORFNames=HGR_07536 {ECO:0000313|EMBL:EGI77147.1};
OS Hylemonella gracilis ATCC 19624.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Comamonadaceae; Hylemonella.
OX NCBI_TaxID=887062 {ECO:0000313|EMBL:EGI77147.1, ECO:0000313|Proteomes:UP000016368};
RN [1] {ECO:0000313|EMBL:EGI77147.1, ECO:0000313|Proteomes:UP000016368}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 19624 {ECO:0000313|EMBL:EGI77147.1,
RC ECO:0000313|Proteomes:UP000016368};
RX PubMed=21673657; DOI=10.1038/emboj.2011.186;
RA Chen S., Beeby M., Murphy G.E., Leadbetter J.R., Hendrixson D.R.,
RA Briegel A., Li Z., Shi J., Tocheva E.I., Muller A., Dobro M.J.,
RA Jensen G.J.;
RT "Structural diversity of bacterial flagellar motors.";
RL EMBO J. 30:2972-2981(2011).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EGI77147.1}.
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DR EMBL; AEGR01000052; EGI77147.1; -; Genomic_DNA.
DR RefSeq; WP_006297543.1; NZ_AEGR01000052.1.
DR AlphaFoldDB; F3KSS8; -.
DR STRING; 887062.HGR_07536; -.
DR eggNOG; COG0841; Bacteria.
DR OrthoDB; 9177212at2; -.
DR Proteomes; UP000016368; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 3.30.70.1430; Multidrug efflux transporter AcrB pore domain; 2.
DR Gene3D; 3.30.70.1440; Multidrug efflux transporter AcrB pore domain; 1.
DR Gene3D; 3.30.70.1320; Multidrug efflux transporter AcrB pore domain like; 1.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR027463; AcrB_DN_DC_subdom.
DR InterPro; IPR001036; Acrflvin-R.
DR PANTHER; PTHR32063; -; 1.
DR PANTHER; PTHR32063:SF0; SWARMING MOTILITY PROTEIN SWRC; 1.
DR Pfam; PF00873; ACR_tran; 1.
DR PRINTS; PR00702; ACRIFLAVINRP.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000016368};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..29
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 372..391
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 398..418
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 469..491
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 497..519
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 580..601
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 907..925
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1021..1040
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1052..1075
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 150..173
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1097 AA; 119245 MW; 610C01AB5AC3F6AC CRC64;
MWFTRVSLKN PVFATMMMMA LVVLGLFSYQ RLQVDQFPNI EFPVVVVSTA YPGASPEIVE
SEVSKKIEEG VNSIAGINTL TSRSYENQSV VIIEFQLTVD GRKAAEDVRE KVAALRPSLR
DEVEEPRVLR FDPSSRAIWS LAVLGDASGQ DSSAGPSQGV SVPPGGSAAG AAASAGAQSW
SPVELTNWAD QVLKKRLENV RGVGAVNLVG GTKREINIYL RPEALEAYGL TPTQIVEAVR
GENQELPLGA VRSSTREIAV QIDARMQRPE DFARIIVARK GGTSGVDTPV RLGQVATIRD
GAQELESLAL YNGQRTLLLT VQKSQDENTI AVIDGLTKAV AELKTQGLLP AGVRLEPIQD
GSRPIRVAVH NVRQTLFEGA MLTVLIVFLF LNSWRSTVIT GLTLPIALIG TFLFMQAFGF
TINMITLMAL SLCVGLLIDD AIVVRENIVR HVQMGKGHYQ AALEGTEEIG LAVLATTLSI
VAVFLPIGFM GGIIGKFFHQ FGITIVAAVL ISMFVSFTLD PMLSSVWPDP NIHQHGASPL
APRNFYDRTV GRVTGWFDRA TDRLAQVYQR LLSWSLGHKL TTLIVAFAIF VASILLVPLL
GSEFVPTADF SETTVNFRTP EGTSIEATEA RARQVQDLLQ REFPEVRYSL ATLNTGNAQG
KNYVSIYVRL VDRVQRQRNV NQISAQLRER LRVVPGITVT HVGLMDAVGG QKQLEFSLQG
QDLRELERLT QTVLEKIAPI PGLVDLDSSA KPGRPTISVQ VNREAAADLG LNVNQIAAAL
RALVAGNTVG NWRASDDQTY DVNVRLAPEA REDMGNLERL PFALGQASDG SARVIRLNQA
ATLVQGTGSS QINRRDLMRE VTITANVHGR SLGEVSADIR QALASTSFPP GYRYRFGGAT
KNMEESFGYA ISALAMAIIF IYMILASQFK SFFQPLALMT SLPLTLIGVV LALMLFGSSL
SMFSIIGVVM LMGLVTKNAI LLLDFAIRAR EGGLDTEGRP VPGMAREQAL LTAAQVRLRP
ILMTTLAMIF GMVPLAFALS EGSEQRAPMG QAVIGGIITS SLLTLVVVPV AYCYLDDFAQ
WLRRLWHGRQ ATPEQTP
//
