ID F3N9K7_9ACTN Unreviewed; 1389 AA.
AC F3N9K7;
DT 28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT 28-JUN-2011, sequence version 1.
DT 27-MAR-2024, entry version 64.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=SGM_0041 {ECO:0000313|EMBL:EGG49701.1};
OS Streptomyces griseoaurantiacus M045.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces; Streptomyces aurantiacus group.
OX NCBI_TaxID=996637 {ECO:0000313|EMBL:EGG49701.1, ECO:0000313|Proteomes:UP000003022};
RN [1] {ECO:0000313|EMBL:EGG49701.1, ECO:0000313|Proteomes:UP000003022}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=M045 {ECO:0000313|EMBL:EGG49701.1,
RC ECO:0000313|Proteomes:UP000003022};
RX PubMed=21551298; DOI=10.1128/JB.05053-11;
RA Li F., Jiang P., Zheng H., Wang S., Zhao G., Qin S., Liu Z.;
RT "Draft genome sequence of the marine bacterium Streptomyces
RT griseoaurantiacus M045, which produces novel manumycin-type antibiotics
RT with a pABA core component.";
RL J. Bacteriol. 193:3417-3418(2011).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EGG49701.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AEYX01000001; EGG49701.1; -; Genomic_DNA.
DR STRING; 996637.SGM_0041; -.
DR eggNOG; COG0745; Bacteria.
DR eggNOG; COG2172; Bacteria.
DR eggNOG; COG2205; Bacteria.
DR eggNOG; COG2208; Bacteria.
DR Proteomes; UP000003022; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd16922; HATPase_EvgS-ArcB-TorS-like; 1.
DR CDD; cd16936; HATPase_RsbW-like; 1.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd00130; PAS; 1.
DR CDD; cd17574; REC_OmpR; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 2.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR Gene3D; 3.60.40.10; PPM-type phosphatase domain; 1.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013656; PAS_4.
DR InterPro; IPR036457; PPM-type-like_dom_sf.
DR InterPro; IPR001932; PPM-type_phosphatase-like_dom.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR43547:SF2; HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE C; 1.
DR PANTHER; PTHR43547; TWO-COMPONENT HISTIDINE KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF13581; HATPase_c_2; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF08448; PAS_4; 2.
DR Pfam; PF00072; Response_reg; 1.
DR Pfam; PF07228; SpoIIE; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00091; PAS; 1.
DR SMART; SM00331; PP2C_SIG; 1.
DR SMART; SM00448; REC; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 2.
DR SUPFAM; SSF52172; CheY-like; 1.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 2.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50112; PAS; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:EGG49701.1};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553, ECO:0000256|PROSITE-
KW ProRule:PRU00169}; Reference proteome {ECO:0000313|Proteomes:UP000003022};
KW Transferase {ECO:0000313|EMBL:EGG49701.1}.
FT DOMAIN 360..577
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT DOMAIN 641..757
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT DOMAIN 773..808
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT MOD_RES 690
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 1389 AA; 149619 MW; F9515E5310986A27 CRC64;
MERSGRSVSR PRAVGDGGVF AACQEVGGDL AEVDWAATPL GPPQEWPQSL QTAVSILLSS
RFPMWMAWGE ELTFFCNAAY RRDTLGRKYP WALGRPASEV WSEIWGDIGP RIEAVLGTGR
ATWDEALLLF LERSGYTEET YHTFSYSPLR DDAGEVVGML CVVNEDTERV IGERRMATLR
DLGSDPSVIR TEQEVLAFVH RQLTRNLKDL PFTLTYLFDG DEARLAGTTG VTPGTPVAPR
SLPVGGPGGV WPVGELAEGE TRGIPLAEAS FGPLPVGDWP ESPLQALVVP LLQQGGAPYG
FLVAALNRYR DLDDHYRGFV ELTAGHIASG IGSARSYQAQ QRRAEELAEL DRAKTTFFSN
ISHELRTPLT LIMGPVEELR TRLSGAGEEV HAELDVIHRN GLRLGKLVNT LLDFSRLEAG
RMQARYEPVE LAAVTAELAS VFRSAVERAG LTLDVDCPAL DEPVYVDRAM WEKVVLNLLS
NALKFTFEGA VRVRVRRSGP DAVVVVADTG TGVPEAEMPR LFERFHRIEN ARARSHEGSG
IGLALVRELV GLHGGTIDAE STEGVGTTFT LRIPFGTAHL PADSVVSEPD GGAAGATADP
YVHEAFRWLP ASEPAPADDG GPREVGAAAV VPGAGPAYSA RVLVADDNAD MREYLARLLT
AAGYQVTEVT DGVEALAAAR RRTPDLVVSD VMMPRLDGLE LVSRLRADPR TASVPVVLLS
ARAGQEASIE GLRAGADDYL VKPFAAAELL ARVRANVELA RLRDHHLRWR TALIDSLQEA
FFVCDESGTV VEINAAFTDI LGYGPEGLPY APVHPWWPHA PADPGAYEQV GDAFARLLES
PRGSYTVPVT HRDGHRLWVA VNFNKAEDPN TGRGVTVGTF RDVTAEHYAV QRETALAALS
TSLSRAADLP EALSAALHVL RSLWHARVVV AAVFGGGDTP ALTATDATLR WEDLPAARRE
ALTALRDRPS LTVVAEDSGA GVRLEHPESP MVVWVDLEGH RPFGSEDQLL LSLLAGHLAQ
GLGRAHQIDQ QRETAIALQR AILGPARLPE GFAVRYEPAT RPLEVGGDWY DTVTLPDGRI
GIVVGDCVGR GLEAASVMGQ LRSACRALLL QDPSPARTLT ALDQFAAGVA GAICTTVFCG
VLEPGSGELT YSSAGHPPGI LVHPDGSSRL LEEGRALPLA VRPGRARPEA TCSLPARATL
LLYTDGLVER RRRPLSAGME QAGEAVKEGR EMPVEDLATA VMSRLAPAGG YDDDVALLLY
RHPAPLEMIF PAESSQLAPV RRALRGWLDQ CDLPPTTVQN VLVAAGEACA NAIEHGHRHT
PGEDVRLRAE ALVDTLRVTV ADSGRWRVPQ RGRNTHRGRG ISLMHALMQE VTVAPGPSGT
TVDMQMRIA
//
