GenomeNet

Database: UniProt
Entry: F3NG74_9ACTN
LinkDB: F3NG74_9ACTN
Original site: F3NG74_9ACTN 
ID   F3NG74_9ACTN            Unreviewed;       295 AA.
AC   F3NG74;
DT   28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT   28-JUN-2011, sequence version 1.
DT   28-FEB-2018, entry version 32.
DE   SubName: Full=Dehydrogenase {ECO:0000313|EMBL:EGG47509.1};
GN   ORFNames=SGM_2138 {ECO:0000313|EMBL:EGG47509.1};
OS   Streptomyces griseoaurantiacus M045.
OC   Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
OC   Streptomyces.
OX   NCBI_TaxID=996637 {ECO:0000313|EMBL:EGG47509.1, ECO:0000313|Proteomes:UP000003022};
RN   [1] {ECO:0000313|EMBL:EGG47509.1, ECO:0000313|Proteomes:UP000003022}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=M045 {ECO:0000313|EMBL:EGG47509.1,
RC   ECO:0000313|Proteomes:UP000003022};
RX   PubMed=21551298; DOI=10.1128/JB.05053-11;
RA   Li F., Jiang P., Zheng H., Wang S., Zhao G., Qin S., Liu Z.;
RT   "Draft genome sequence of the marine bacterium Streptomyces
RT   griseoaurantiacus M045, which produces novel manumycin-type
RT   antibiotics with a pABA core component.";
RL   J. Bacteriol. 193:3417-3418(2011).
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:EGG47509.1}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; AEYX01000031; EGG47509.1; -; Genomic_DNA.
DR   ProteinModelPortal; F3NG74; -.
DR   STRING; 996637.SGM_2138; -.
DR   EnsemblBacteria; EGG47509; EGG47509; SGM_2138.
DR   eggNOG; ENOG4105ESE; Bacteria.
DR   eggNOG; COG2084; LUCA.
DR   OrthoDB; POG091H02BQ; -.
DR   BioCyc; SGRI996637:G12JX-5214-MONOMER; -.
DR   Proteomes; UP000003022; Unassembled WGS sequence.
DR   GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR   GO; GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:InterPro.
DR   Gene3D; 1.10.1040.10; -; 1.
DR   InterPro; IPR002204; 3-OH-isobutyrate_DH-rel_CS.
DR   InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR   InterPro; IPR013328; 6PGD_dom2.
DR   InterPro; IPR006115; 6PGDH_NADP-bd.
DR   InterPro; IPR015815; HIBADH-related.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR029154; NADP-bd.
DR   Pfam; PF14833; NAD_binding_11; 1.
DR   Pfam; PF03446; NAD_binding_2; 1.
DR   PIRSF; PIRSF000103; HIBADH; 1.
DR   SUPFAM; SSF48179; SSF48179; 1.
DR   SUPFAM; SSF51735; SSF51735; 1.
DR   PROSITE; PS00895; 3_HYDROXYISOBUT_DH; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000003022};
KW   Reference proteome {ECO:0000313|Proteomes:UP000003022}.
FT   DOMAIN        6    164       NAD_binding_2. {ECO:0000259|Pfam:
FT                                PF03446}.
FT   DOMAIN      172    288       NAD_binding_11. {ECO:0000259|Pfam:
FT                                PF14833}.
FT   ACT_SITE    174    174       {ECO:0000256|PIRSR:PIRSR000103-1}.
SQ   SEQUENCE   295 AA;  30977 MW;  DFA11AE299BD1011 CRC64;
     MIEMHTVGFL GLGVMGTPMA LNLARAGTPL LVWNRTPHRA EPLRAAGATV AGSPAEVFAG
     ADTVVLMLAN DRATDAVLER GTPAFAGLAA GRTVVNVGTT APEYSRALAA DLRAAGGRYV
     EAPVSGSRVP AEQGRLVAML AGEEKDVADV TPLLAPLCHE VFACGPVPNA LLMKLAVNLF
     LITQVTGLTE AFHFAERHRL DRRLFLDVLD AGPMASAVSR MKAPKLLHGD FAVQAAAADV
     LMNNRLIAEA ARARGVASPL LDACHDLFAE TVALGHGGED MVAVLRALED RTRRL
//
DBGET integrated database retrieval system