ID F3NLM6_9ACTN Unreviewed; 268 AA.
AC F3NLM6;
DT 28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT 28-JUN-2011, sequence version 1.
DT 24-JAN-2024, entry version 43.
DE SubName: Full=Hydrolase {ECO:0000313|EMBL:EGG45952.1};
GN ORFNames=SGM_4040 {ECO:0000313|EMBL:EGG45952.1};
OS Streptomyces griseoaurantiacus M045.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces; Streptomyces aurantiacus group.
OX NCBI_TaxID=996637 {ECO:0000313|EMBL:EGG45952.1, ECO:0000313|Proteomes:UP000003022};
RN [1] {ECO:0000313|EMBL:EGG45952.1, ECO:0000313|Proteomes:UP000003022}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=M045 {ECO:0000313|EMBL:EGG45952.1,
RC ECO:0000313|Proteomes:UP000003022};
RX PubMed=21551298; DOI=10.1128/JB.05053-11;
RA Li F., Jiang P., Zheng H., Wang S., Zhao G., Qin S., Liu Z.;
RT "Draft genome sequence of the marine bacterium Streptomyces
RT griseoaurantiacus M045, which produces novel manumycin-type antibiotics
RT with a pABA core component.";
RL J. Bacteriol. 193:3417-3418(2011).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EGG45952.1}.
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DR EMBL; AEYX01000039; EGG45952.1; -; Genomic_DNA.
DR RefSeq; WP_006141830.1; NZ_AEYX01000039.1.
DR AlphaFoldDB; F3NLM6; -.
DR STRING; 996637.SGM_4040; -.
DR eggNOG; COG2755; Bacteria.
DR Proteomes; UP000003022; Unassembled WGS sequence.
DR GO; GO:0016788; F:hydrolase activity, acting on ester bonds; IEA:InterPro.
DR CDD; cd01823; SEST_like; 1.
DR Gene3D; 3.40.50.1110; SGNH hydrolase; 1.
DR InterPro; IPR037460; SEST-like.
DR InterPro; IPR013830; SGNH_hydro.
DR InterPro; IPR036514; SGNH_hydro_sf.
DR PANTHER; PTHR37981; LIPASE 2; 1.
DR PANTHER; PTHR37981:SF1; SGNH_HYDRO DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF13472; Lipase_GDSL_2; 1.
DR SUPFAM; SSF52266; SGNH hydrolase; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|PIRSR:PIRSR637460-2};
KW Hydrolase {ECO:0000313|EMBL:EGG45952.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000003022};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..29
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 30..268
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003300749"
FT DOMAIN 40..256
FT /note="SGNH hydrolase-type esterase"
FT /evidence="ECO:0000259|Pfam:PF13472"
FT ACT_SITE 44
FT /note="Nucleophile"
FT /evidence="ECO:0000256|PIRSR:PIRSR637460-1"
FT ACT_SITE 250
FT /evidence="ECO:0000256|PIRSR:PIRSR637460-1"
FT DISULFID 61..86
FT /evidence="ECO:0000256|PIRSR:PIRSR637460-2"
FT DISULFID 127..135
FT /evidence="ECO:0000256|PIRSR:PIRSR637460-2"
FT DISULFID 185..231
FT /evidence="ECO:0000256|PIRSR:PIRSR637460-2"
SQ SEQUENCE 268 AA; 27611 MW; 9A7947F93D369558 CRC64;
MRRSRIAAYV TSLLLAVGLT LTGAATAQAS SVAAGTDYVA LGDSYSSGVG SGSYLSSGGD
CKRSTKSYPY LWQAAHSVSS FSFLACSGAT TSDVMSGQLS TLTSATDLVS ISVGGNDAGF
ADVMTTCVLQ SDATCLARID TARAFVDSTL PGRLDTVYSA IRAKAPAARV VVLGYPRFYR
LGTTCLGLSA TKRAAINDAA DRLDAALAKR AADHGFAFGD VRTTFTGHEL CSGSAWLHSL
ELLDIGESYH PTAAGQSGGY LPLLNSLA
//
