ID F3NPT4_9ACTN Unreviewed; 798 AA.
AC F3NPT4;
DT 28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT 28-JUN-2011, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE SubName: Full=Alpha-N-acetylglucosaminidase {ECO:0000313|EMBL:EGG44604.1};
GN ORFNames=SGM_5419 {ECO:0000313|EMBL:EGG44604.1};
OS Streptomyces griseoaurantiacus M045.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces; Streptomyces aurantiacus group.
OX NCBI_TaxID=996637 {ECO:0000313|EMBL:EGG44604.1, ECO:0000313|Proteomes:UP000003022};
RN [1] {ECO:0000313|EMBL:EGG44604.1, ECO:0000313|Proteomes:UP000003022}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=M045 {ECO:0000313|EMBL:EGG44604.1,
RC ECO:0000313|Proteomes:UP000003022};
RX PubMed=21551298; DOI=10.1128/JB.05053-11;
RA Li F., Jiang P., Zheng H., Wang S., Zhao G., Qin S., Liu Z.;
RT "Draft genome sequence of the marine bacterium Streptomyces
RT griseoaurantiacus M045, which produces novel manumycin-type antibiotics
RT with a pABA core component.";
RL J. Bacteriol. 193:3417-3418(2011).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EGG44604.1}.
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DR EMBL; AEYX01000043; EGG44604.1; -; Genomic_DNA.
DR AlphaFoldDB; F3NPT4; -.
DR STRING; 996637.SGM_5419; -.
DR eggNOG; COG3669; Bacteria.
DR Proteomes; UP000003022; Unassembled WGS sequence.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:UniProt.
DR Gene3D; 3.30.379.10; Chitobiase/beta-hexosaminidase domain 2-like; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 1.20.120.670; N-acetyl-b-d-glucoasminidase; 1.
DR InterPro; IPR029018; Hex-like_dom2.
DR InterPro; IPR007781; NAGLU.
DR InterPro; IPR024732; NAGLU_C.
DR InterPro; IPR024240; NAGLU_N.
DR InterPro; IPR024733; NAGLU_tim-barrel.
DR InterPro; IPR006311; TAT_signal.
DR PANTHER; PTHR12872; ALPHA-N-ACETYLGLUCOSAMINIDASE; 1.
DR PANTHER; PTHR12872:SF1; ALPHA-N-ACETYLGLUCOSAMINIDASE; 1.
DR Pfam; PF05089; NAGLU; 1.
DR Pfam; PF12972; NAGLU_C; 1.
DR Pfam; PF12971; NAGLU_N; 1.
DR PROSITE; PS51318; TAT; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000003022};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..798
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5039484552"
FT DOMAIN 45..121
FT /note="Alpha-N-acetylglucosaminidase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF12971"
FT DOMAIN 138..473
FT /note="Alpha-N-acetylglucosaminidase tim-barrel"
FT /evidence="ECO:0000259|Pfam:PF05089"
FT DOMAIN 482..747
FT /note="Alpha-N-acetylglucosaminidase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF12972"
FT REGION 750..798
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 798 AA; 87397 MW; A2A5177560E20DB4 CRC64;
MPLARRSLLS ALAAGSAGAA VAGAATLSEG GPALGAGGGD TGARAAAAAT RRLLPRHWHQ
FSFRTEGGRD TFTVSGEAGR LRITGGTPGT QLTGLNWYLR HVADADVNWA GEQLDLPRIL
PGMPGGTAVT RRAGVPHRFA LNDTNEGYTG PYHDWSYWER ELDVLALHGY NQVLVTVGAD
ALYHRVFQEF GYGEEELRAW LPGPAHQPWW LLQNMASFPT SAALREPVST QLLDARAVLG
RRLADRLREL GMVPVLPGYF GTVPPGFAAR NRGARTVPQG TWMGFDRPDW LDPRTDLFAR
VAAAFYRVQG ELFGASTHYK MDLLHEGGTA GDVPVGEAAK GVERALRRAR PDAVWVLLGW
RHNPPRAILD AVASGGPDGA AGRERLLVVD GLSDRFPTVT DREADWGGVP YAFGSIWNFG
GHTTLGANTP DWARLYEAWR TKEGSALRGI ALLPEAADNN PAAFALFSEL PWHEGELDLK
AWFARWARSR YGAYDAHAEA AWDVLRRTAY GTTRADSWSE GADGLFGARP SLTARRAASW
SPKELRYDAH EFERALDELL KVRPGLRESS AYRRDLLDVA RQCLSNRSRA LLPRIARACA
ARDVKAFDAA SGDWLSLMDL LERLVGTDAR HLLGRWTAQA RAWGADEAER DRLQYDALSL
LTVWGTRQGA EAGLRDYANR EWAGLVGGLY RLRWSTYFTE LRAALTEGRA PAAVDWYALE
ERWTRAPGRL ATRPAGDVHR IAREVRERLR ATARPARRHG ARPGTAAPDP TGTAPRSDRD
GAADGVPPVA YAPYATLK
//
