ID F3NPT9_9ACTN Unreviewed; 941 AA.
AC F3NPT9;
DT 28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT 28-JUN-2011, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE SubName: Full=Transcriptional regulator {ECO:0000313|EMBL:EGG44609.1};
GN ORFNames=SGM_5424 {ECO:0000313|EMBL:EGG44609.1};
OS Streptomyces griseoaurantiacus M045.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces; Streptomyces aurantiacus group.
OX NCBI_TaxID=996637 {ECO:0000313|EMBL:EGG44609.1, ECO:0000313|Proteomes:UP000003022};
RN [1] {ECO:0000313|EMBL:EGG44609.1, ECO:0000313|Proteomes:UP000003022}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=M045 {ECO:0000313|EMBL:EGG44609.1,
RC ECO:0000313|Proteomes:UP000003022};
RX PubMed=21551298; DOI=10.1128/JB.05053-11;
RA Li F., Jiang P., Zheng H., Wang S., Zhao G., Qin S., Liu Z.;
RT "Draft genome sequence of the marine bacterium Streptomyces
RT griseoaurantiacus M045, which produces novel manumycin-type antibiotics
RT with a pABA core component.";
RL J. Bacteriol. 193:3417-3418(2011).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EGG44609.1}.
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DR EMBL; AEYX01000043; EGG44609.1; -; Genomic_DNA.
DR RefSeq; WP_006143283.1; NZ_AEYX01000043.1.
DR AlphaFoldDB; F3NPT9; -.
DR STRING; 996637.SGM_5424; -.
DR eggNOG; COG2197; Bacteria.
DR Proteomes; UP000003022; Unassembled WGS sequence.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd06170; LuxR_C_like; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR041664; AAA_16.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR000792; Tscrpt_reg_LuxR_C.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR16305; TESTICULAR SOLUBLE ADENYLYL CYCLASE; 1.
DR PANTHER; PTHR16305:SF35; TRANSCRIPTIONAL ACTIVATOR DOMAIN; 1.
DR Pfam; PF13191; AAA_16; 1.
DR Pfam; PF00196; GerE; 1.
DR PRINTS; PR00038; HTHLUXR.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00421; HTH_LUXR; 1.
DR SUPFAM; SSF46894; C-terminal effector domain of the bipartite response regulators; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF48452; TPR-like; 1.
DR PROSITE; PS50043; HTH_LUXR_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000003022}.
FT DOMAIN 874..939
FT /note="HTH luxR-type"
FT /evidence="ECO:0000259|PROSITE:PS50043"
SQ SEQUENCE 941 AA; 99508 MW; 9E6FD79458EA4B20 CRC64;
MGRESEKPGR ARPTPLVGRE DLLAGARDQL DRGGSVLVHG PAGIGKSAVL RALAAEHAAT
AHTVLRCSAT ESESHLPFLA LADLLGLVAA DVADRLPAAQ RTALESALTG RGESTLERDG
LALRLAVLST LRALAARGPV LIVADDLQWL DPASTELLGF AARRLGDMPI RMLCAARTGS
DPRGPEHDRF LRATPPDTLA VRVGPLSRAQ TAELLARRGF GALPRSTVRD IHRTSGGNPL
FALELGRALA ENPVPPGPGE PLPVPTSLRA LVLNRLEALS AEARRTLLVA SAGARPTTAL
LHAAGRENAE AEIARAAALG LLVTDRDSPG VRFAHPLISA ALYAEADPEE RRSAHAALST
AASDPIERAR HLALATEGTD PRVAERLGEA AAAARERGAP SVAAGLGLLA ARHTPPDAEP
GPSVWRLQAA EDALIAGETD LARDLARQVL ADASAPAERV RAWIVVIESA GHALGEVDAA
YPQALADAGE DPRLLALVHY QLAWRATIYE GDFAEARQEA ARAASLAERA GDRRTELMAL
AFQAQAETLM GHPDAPATIK RAMREPQDPR VACDHNGVGA ARFRWLIMSD RLAEARTTIS
ALLREVRRRG MVESEVHFLR GLAETELRAG HCARALDLAR ESLRLARDTG IGQAAAAMFT
SLAEAAGGDV ERAGALAREA VSRAEDHGDQ VYLSRALGAL GHAQLVAGDA AGAVRSLRRV
RDLEEQLGVT DPARGRWHGD LAEALVRVGE PAEAQRLVDV TRVRASALGR ESVLAVLDRA
EALARAARGD VDGAVRQLSS ARDRLGRLGY GLEEARAVYA LAGLRGRRPG AASYEEAARL
FRRCRAVPWL RQAEAQPVAE PGTPTAVRAG ASPGAEALGG LAATERQVAA LVMEGATNRE
IAARLFISVK TVEATLTRVY RKLGIRSRVD IVRLAAARRA E
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