ID F3P5M6_9ACTO Unreviewed; 570 AA.
AC F3P5M6;
DT 28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT 28-JUN-2011, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE SubName: Full=Trypsin {ECO:0000313|EMBL:EGF57784.1};
GN ORFNames=HMPREF9056_00331 {ECO:0000313|EMBL:EGF57784.1};
OS Actinomyces sp. oral taxon 170 str. F0386.
OC Bacteria; Actinomycetota; Actinomycetes; Actinomycetales; Actinomycetaceae;
OC Actinomyces.
OX NCBI_TaxID=762963 {ECO:0000313|EMBL:EGF57784.1, ECO:0000313|Proteomes:UP000004404};
RN [1] {ECO:0000313|EMBL:EGF57784.1, ECO:0000313|Proteomes:UP000004404}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=F0386 {ECO:0000313|EMBL:EGF57784.1,
RC ECO:0000313|Proteomes:UP000004404};
RA Weinstock G., Sodergren E., Clifton S., Fulton L., Fulton B., Courtney L.,
RA Fronick C., Harrison M., Strong C., Farmer C., Delahaunty K., Markovic C.,
RA Hall O., Minx P., Tomlinson C., Mitreva M., Hou S., Chen J., Wollam A.,
RA Pepin K.H., Johnson M., Bhonagiri V., Zhang X., Suruliraj S., Warren W.,
RA Chinwalla A., Mardis E.R., Wilson R.K.;
RL Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EGF57784.1}.
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DR EMBL; AFBL01000008; EGF57784.1; -; Genomic_DNA.
DR RefSeq; WP_009402125.1; NZ_GL882511.1.
DR AlphaFoldDB; F3P5M6; -.
DR STRING; 762963.HMPREF9056_00331; -.
DR MEROPS; S01.494; -.
DR eggNOG; COG0265; Bacteria.
DR HOGENOM; CLU_020120_3_8_11; -.
DR OrthoDB; 9758917at2; -.
DR Proteomes; UP000004404; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR CDD; cd00987; PDZ_serine_protease; 1.
DR Gene3D; 2.30.42.10; -; 1.
DR Gene3D; 2.40.10.120; -; 1.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR009003; Peptidase_S1_PA.
DR InterPro; IPR001940; Peptidase_S1C.
DR PANTHER; PTHR43343; PEPTIDASE S12; 1.
DR PANTHER; PTHR43343:SF3; PROTEASE DO-LIKE 8, CHLOROPLASTIC; 1.
DR Pfam; PF13180; PDZ_2; 1.
DR Pfam; PF13365; Trypsin_2; 1.
DR PRINTS; PR00834; PROTEASES2C.
DR SMART; SM00228; PDZ; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 1.
DR SUPFAM; SSF50494; Trypsin-like serine proteases; 1.
DR PROSITE; PS50106; PDZ; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 192..214
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 463..555
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT REGION 1..161
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 25..43
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 91..160
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 570 AA; 56651 MW; 450DF8EFC2335520 CRC64;
MSGYDETNPE AYRPAEPGQA AEGSHTGVGS PSALSQGGSA AAASGSEPPS VPPHQAGYED
LSQAYGAGAS QDAPALPGAA PAVAGGRTEY TQQLPAGQAT SQMPADQPTS VYAASQQQGQ
YPAYSQGQQA PYNQSASQQS HPGQQAHLGS PYTSVPTTPG GYASAGAGES FYATSNVTGS
ENGSKRRRGP GWFALVASVV VASLLGAGGA VGAIKALDAR DGGASQRSSA APTAIATGDT
TKTVNSAGQA PDWEAVSAAV SNAVVSIAIA TDKGTALGSG VIFDKEGHII TNNHVVASAS
QIQVTLADGR VYEAETTGTD PATDLAVIQL KDAPDDLTVA QLGDSDKLTT GQDVMAIGNP
LGLSSTVTTG IVSALDRPVV NAQGEGGEGD SGGGSSASAV YTNAIQIDAA INPGNSGGPL
FDEKGRVIGI TSSIATMGSS SSGEAGSGSI GIGFAIPVKL ADKVAKQLIE SGSATHAYLG
VSLDTDAAEA DGAKRAGARI TSVESGSPAD KAGLKKGDVV IAIDGKTTSQ GSALTGYVRQ
YSANDKVKLA VIRDSKKQDI DVTLAERKDS
//
