ID   F3P7A3_9ACTO            Unreviewed;       451 AA.
AC   F3P7A3;
DT   28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT   28-JUN-2011, sequence version 1.
DT   24-JAN-2024, entry version 35.
DE   SubName: Full=NCS1 nucleoside transporter family protein {ECO:0000313|EMBL:EGF56280.1};
GN   ORFNames=HMPREF9056_00917 {ECO:0000313|EMBL:EGF56280.1};
OS   Actinomyces sp. oral taxon 170 str. F0386.
OC   Bacteria; Actinomycetota; Actinomycetes; Actinomycetales; Actinomycetaceae;
OC   Actinomyces.
OX   NCBI_TaxID=762963 {ECO:0000313|EMBL:EGF56280.1, ECO:0000313|Proteomes:UP000004404};
RN   [1] {ECO:0000313|EMBL:EGF56280.1, ECO:0000313|Proteomes:UP000004404}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=F0386 {ECO:0000313|EMBL:EGF56280.1,
RC   ECO:0000313|Proteomes:UP000004404};
RA   Weinstock G., Sodergren E., Clifton S., Fulton L., Fulton B., Courtney L.,
RA   Fronick C., Harrison M., Strong C., Farmer C., Delahaunty K., Markovic C.,
RA   Hall O., Minx P., Tomlinson C., Mitreva M., Hou S., Chen J., Wollam A.,
RA   Pepin K.H., Johnson M., Bhonagiri V., Zhang X., Suruliraj S., Warren W.,
RA   Chinwalla A., Mardis E.R., Wilson R.K.;
RL   Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the purine-cytosine permease (2.A.39) family.
CC       {ECO:0000256|ARBA:ARBA00008974}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EGF56280.1}.
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DR   EMBL; AFBL01000025; EGF56280.1; -; Genomic_DNA.
DR   AlphaFoldDB; F3P7A3; -.
DR   STRING; 762963.HMPREF9056_00917; -.
DR   eggNOG; COG1953; Bacteria.
DR   HOGENOM; CLU_021555_0_2_11; -.
DR   Proteomes; UP000004404; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   CDD; cd11555; SLC-NCS1sbd_u1; 1.
DR   Gene3D; 1.10.4160.10; Hydantoin permease; 1.
DR   InterPro; IPR001248; Pur-cyt_permease.
DR   InterPro; IPR045225; Uracil/uridine/allantoin_perm.
DR   PANTHER; PTHR30618; NCS1 FAMILY PURINE/PYRIMIDINE TRANSPORTER; 1.
DR   PANTHER; PTHR30618:SF6; PERMEASE-RELATED; 1.
DR   Pfam; PF02133; Transp_cyt_pur; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        7..25
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        31..54
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        66..90
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        110..140
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        152..174
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        194..214
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        235..257
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        277..302
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        314..334
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        340..365
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        394..414
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        420..436
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   451 AA;  48923 MW;  E7726DF9B8F94C71 CRC64;
     MNDAHNASNY TFAAGLFIGT GAIVGMTPLS IVIGVFIATF IIFIACCISG LMGYETGAPY
     PVISRVTWGV WGANFPALVR GVVAIAWYGI QTYLASISLE LLLMRIFPPM QHWTASFVGL
     RLSGWVAFLI LSGIQLIIVW RGMEAVRHFQ GAAGPIIWVI MIGLGVWMLS QAGWDFRWTV
     NADNVTPPIG TQLYQIFVTV GLTIGTLATL MLNFSDFARY APSRRSVVMG NVLGLPLNWT
     AFALTSVLCS AAAIKVYGEA FHDPGDLLSR IDNDVVFYVV SIAFIVATVG VNIVANFVSA
     AFDLSNLNPR RISFRVGGIV SVIASIVVTP WNLYGSPTAI NYFLGSLGAL LGPFFGILTL
     DYFYYKRSRV DLRDLYSPNP EGRYFYRGGL NTDALLGFIP AAIVALCIAL VPAFSKVSPF
     SWFIAAPLGA LCYWIVQTLR GNKPLPTGSG D
//