ID F3PF80_9BACE Unreviewed; 631 AA.
AC F3PF80;
DT 28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT 28-JUN-2011, sequence version 1.
DT 24-JAN-2024, entry version 38.
DE SubName: Full=Precorrin-4 C(11)-methyltransferase {ECO:0000313|EMBL:EGF53909.1};
GN ORFNames=HMPREF9445_00645 {ECO:0000313|EMBL:EGF53909.1};
OS Bacteroides clarus YIT 12056.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae;
OC Bacteroides.
OX NCBI_TaxID=762984 {ECO:0000313|EMBL:EGF53909.1, ECO:0000313|Proteomes:UP000010321};
RN [1] {ECO:0000313|EMBL:EGF53909.1, ECO:0000313|Proteomes:UP000010321}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=YIT 12056 {ECO:0000313|EMBL:EGF53909.1,
RC ECO:0000313|Proteomes:UP000010321};
RA Weinstock G., Sodergren E., Clifton S., Fulton L., Fulton B., Courtney L.,
RA Fronick C., Harrison M., Strong C., Farmer C., Delahaunty K., Markovic C.,
RA Hall O., Minx P., Tomlinson C., Mitreva M., Hou S., Chen J., Wollam A.,
RA Pepin K.H., Johnson M., Bhonagiri V., Zhang X., Suruliraj S., Warren W.,
RA Chinwalla A., Mardis E.R., Wilson R.K.;
RL Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EGF53909.1}.
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DR EMBL; AFBM01000007; EGF53909.1; -; Genomic_DNA.
DR AlphaFoldDB; F3PF80; -.
DR STRING; 762984.SAMN05444376_1890; -.
DR eggNOG; COG2073; Bacteria.
DR eggNOG; COG2875; Bacteria.
DR HOGENOM; CLU_028397_1_0_10; -.
DR Proteomes; UP000010321; Unassembled WGS sequence.
DR GO; GO:0046026; F:precorrin-4 C11-methyltransferase activity; IEA:InterPro.
DR GO; GO:0009236; P:cobalamin biosynthetic process; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd11641; Precorrin-4_C11-MT; 1.
DR Gene3D; 3.40.50.11220; -; 1.
DR Gene3D; 3.30.420.180; CobE/GbiG C-terminal domain; 1.
DR InterPro; IPR000878; 4pyrrol_Mease.
DR InterPro; IPR035996; 4pyrrol_Methylase_sf.
DR InterPro; IPR014777; 4pyrrole_Mease_sub1.
DR InterPro; IPR014776; 4pyrrole_Mease_sub2.
DR InterPro; IPR021745; CbiG_mid.
DR InterPro; IPR021744; CbiG_N.
DR InterPro; IPR006362; Cbl_synth_CobM/CibF.
DR InterPro; IPR002750; CobE/GbiG_C.
DR InterPro; IPR036518; CobE/GbiG_C_sf.
DR InterPro; IPR038029; GbiG_N_sf.
DR NCBIfam; TIGR01465; cobM_cbiF; 1.
DR PANTHER; PTHR37477; COBALT-PRECORRIN-5A HYDROLASE; 1.
DR PANTHER; PTHR37477:SF1; COBALT-PRECORRIN-5A HYDROLASE; 1.
DR Pfam; PF01890; CbiG_C; 1.
DR Pfam; PF11761; CbiG_mid; 1.
DR Pfam; PF11760; CbiG_N; 1.
DR Pfam; PF00590; TP_methylase; 1.
DR SUPFAM; SSF159672; CbiG N-terminal domain-like; 1.
DR SUPFAM; SSF159664; CobE/GbiG C-terminal domain-like; 1.
DR SUPFAM; SSF53790; Tetrapyrrole methylase; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:EGF53909.1};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:EGF53909.1}.
FT DOMAIN 60..140
FT /note="Cobalamin synthesis G N-terminal"
FT /evidence="ECO:0000259|Pfam:PF11760"
FT DOMAIN 145..256
FT /note="Cobalamin biosynthesis central region"
FT /evidence="ECO:0000259|Pfam:PF11761"
FT DOMAIN 259..375
FT /note="CobE/GbiG C-terminal"
FT /evidence="ECO:0000259|Pfam:PF01890"
FT DOMAIN 388..591
FT /note="Tetrapyrrole methylase"
FT /evidence="ECO:0000259|Pfam:PF00590"
SQ SEQUENCE 631 AA; 69628 MW; 439F0E98262F9EEF CRC64;
MKTDIPVMKA DAPRMKTAIM LVSEAGLASA RLLLKEFPEA EIFTPRHEDG CTHIESTGSF
TAENFNRYDT FIFIGAMGIC VRSIAPCVKN KYTDPAVICV DSTGRYAISV LSGHIGGANE
LTAAIAGALG AEPVITTQSD LTGLWALDKL PGRFGWFPIL NVDASALRLA ELAQTREEKM
KACMNEPIRL FVSGKPTALL LEVRDKGTDW LEAHLPPHVE VFYRLKDIEV SRFQLVLCVS
PQVHYIEGTP SICYVPRMVH VGIGLARQAG PVKEVTEEIL DRLKEYGIPR QAIASIATID
AKRDEPVVKS LQKEYDVCFY TAEELAATDV PHPSKTVMKH MGTPSVSEAA ALLSSGNSEL
IMPKRKGGNY TVAAAINIRA LRRGHIEIVG AGPGDPDLIS VRGREMLEKA DLILYAGSLV
PRELTLCAKP GATVRSSASM DLEEQFALMK EFYDKGKFIV RLHTGDPCIY GAIQEQMNYF
DRYGMSYHIT PGISSFQAAA AALKSQFTIP EKVQSIILTR GEGRTPMPER EKLHLMARSQ
STMCIFLSAG IAEQVQAELL QEYPETTPVA VCYHLTWPDE RIFRGKLKDL ARIVKENNLT
LTTMIVVGEA IGNREGLSRL YAHEFKHLFR K
//
