ID   F3PW82_9BACE            Unreviewed;       359 AA.
AC   F3PW82;
DT   28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT   28-JUN-2011, sequence version 1.
DT   24-JAN-2024, entry version 37.
DE   RecName: Full=Metallo-beta-lactamase domain-containing protein {ECO:0000259|Pfam:PF12706};
GN   ORFNames=HMPREF9446_03017 {ECO:0000313|EMBL:EGF52431.1};
OS   Bacteroides fluxus YIT 12057.
OC   Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae;
OC   Bacteroides.
OX   NCBI_TaxID=763034 {ECO:0000313|EMBL:EGF52431.1, ECO:0000313|Proteomes:UP000003416};
RN   [1] {ECO:0000313|EMBL:EGF52431.1, ECO:0000313|Proteomes:UP000003416}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=YIT 12057 {ECO:0000313|EMBL:EGF52431.1,
RC   ECO:0000313|Proteomes:UP000003416};
RA   Weinstock G., Sodergren E., Clifton S., Fulton L., Fulton B., Courtney L.,
RA   Fronick C., Harrison M., Strong C., Farmer C., Delahaunty K., Markovic C.,
RA   Hall O., Minx P., Tomlinson C., Mitreva M., Hou S., Chen J., Wollam A.,
RA   Pepin K.H., Johnson M., Bhonagiri V., Zhang X., Suruliraj S., Warren W.,
RA   Chinwalla A., Mardis E.R., Wilson R.K.;
RL   Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EGF52431.1}.
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DR   EMBL; AFBN01000095; EGF52431.1; -; Genomic_DNA.
DR   AlphaFoldDB; F3PW82; -.
DR   STRING; 763034.HMPREF9446_03017; -.
DR   eggNOG; COG2220; Bacteria.
DR   HOGENOM; CLU_020884_0_2_10; -.
DR   Proteomes; UP000003416; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0070290; F:N-acylphosphatidylethanolamine-specific phospholipase D activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR   InterPro; IPR001279; Metallo-B-lactamas.
DR   InterPro; IPR024884; NAPE-PLD.
DR   InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR   PANTHER; PTHR15032; N-ACYL-PHOSPHATIDYLETHANOLAMINE-HYDROLYZING PHOSPHOLIPASE D; 1.
DR   PANTHER; PTHR15032:SF4; N-ACYL-PHOSPHATIDYLETHANOLAMINE-HYDROLYZING PHOSPHOLIPASE D; 1.
DR   Pfam; PF12706; Lactamase_B_2; 1.
DR   PIRSF; PIRSF038896; NAPE-PLD; 1.
DR   SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000003416};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        6..25
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          122..316
FT                   /note="Metallo-beta-lactamase"
FT                   /evidence="ECO:0000259|Pfam:PF12706"
SQ   SEQUENCE   359 AA;  41365 MW;  7417CDEC335B4F5A CRC64;
     MNHKKMIIII TSIIAALVIG TILFLHQPSF GRLPQGERLE RIKQSPNYRN GEFRNQSPTE
     LMTGKGNRWQ TLFGFLLGNK MNIHPDTPVA TIKTDLQNLP KDKDLMIWFG HSSYLLQISG
     KRILVDPVFY AASPVSWLYK PFKGTDIYKP EDMPEIDYLI VSHDHYDHLE YRTIVALKER
     VGKVICPLGV GEHFECWGYD KKQLVELDWK ENVTPSNGFT VHCLPTRHFS GRSLKANQTL
     WASFLIDTPS LKVYIGGDGG YDRHFKEIGK QYPNIDLAIL ENGQYNEDWK YIHTMPVQLA
     QVAKDLKAKN IITVHHSKYA LARHRWDEPL QNELTIIQDD RFNLLTPIIG EVTLIKTNK
//