ID F3Y924_MELPT Unreviewed; 525 AA.
AC F3Y924;
DT 28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT 28-JUN-2011, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE SubName: Full=UDP-N-acetylglucosamine 4,6-dehydratase {ECO:0000313|EMBL:BAK21002.1};
DE EC=4.2.1.- {ECO:0000313|EMBL:BAK21002.1};
GN OrderedLocusNames=MPTP_0527 {ECO:0000313|EMBL:BAK21002.1};
OS Melissococcus plutonius (strain ATCC 35311 / CIP 104052 / LMG 20360 / NCIMB
OS 702443).
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
OC Melissococcus.
OX NCBI_TaxID=940190 {ECO:0000313|EMBL:BAK21002.1, ECO:0000313|Proteomes:UP000008456};
RN [1] {ECO:0000313|EMBL:BAK21002.1, ECO:0000313|Proteomes:UP000008456}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 35311 / CIP 104052 / LMG 20360 / NCIMB 702443
RC {ECO:0000313|Proteomes:UP000008456};
RX PubMed=21622755; DOI=10.1128/JB.05151-11;
RA Okumura K., Arai R., Okura M., Kirikae T., Takamatsu D., Osaki M.,
RA Miyoshi-Akiyama T.;
RT "Complete genome sequence of Melissococcus plutonius ATCC 35311.";
RL J. Bacteriol. 193:4029-4030(2011).
RN [2]
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=ATCC 35311;
RA Okumura K., Arai R., Osaki M., Okura M., Kirikae T., Takamatsu D.,
RA Akiyama T.;
RT "Whole genome sequence of Melissococcus plutonius ATCC 35311.";
RL Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the polysaccharide synthase family.
CC {ECO:0000256|ARBA:ARBA00007430}.
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DR EMBL; AP012200; BAK21002.1; -; Genomic_DNA.
DR AlphaFoldDB; F3Y924; -.
DR STRING; 940190.MPTP_0527; -.
DR KEGG; mps:MPTP_0527; -.
DR HOGENOM; CLU_013560_5_2_9; -.
DR Proteomes; UP000008456; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR CDD; cd05237; UDP_invert_4-6DH_SDR_e; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR003869; Polysac_CapD-like.
DR PANTHER; PTHR43318:SF1; POLYSACCHARIDE BIOSYNTHESIS PROTEIN EPSC-RELATED; 1.
DR PANTHER; PTHR43318; UDP-N-ACETYLGLUCOSAMINE 4,6-DEHYDRATASE; 1.
DR Pfam; PF13727; CoA_binding_3; 1.
DR Pfam; PF02719; Polysacc_synt_2; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 2.
PE 3: Inferred from homology;
KW Lyase {ECO:0000313|EMBL:BAK21002.1}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000008456};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 21..42
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 205..487
FT /note="Polysaccharide biosynthesis protein CapD-like"
FT /evidence="ECO:0000259|Pfam:PF02719"
SQ SEQUENCE 525 AA; 58293 MW; 7B5CC530578C3A16 CRC64;
MTAASICEFF LLLLLDLNDD YRFVLLTYLV ANFLIITSRL VWCTIIEAKS KSKVHGNQVY
PKQTLIIGAG EAGQLLLNSL HTSAKNSGIK VIGLIDDAPD KYHTYLSGVR VLGNTKQIPN
IIKDYDIEML TLAIPSIHPE QLKRILDIIT PLGLPVNSMP DLEEVASGNI TISRLKEIDV
IDLLGREEVQ LNIEQIKDQL SNKVILVTGA GGSIGSEICR QVMNFNPKTL ILLGHGENSI
YLIEKELHNT FQHTSTEIIP IIADIQDKQQ MVEIMKRFHP QIVYHAAAHK HVPLMEYNPQ
SAIKNNIFGT KNTAEAAKAA NVANFVMIST DKAVNPPNIM GATKRVAELI ITNLNKTGNT
KFCAVRFGNV LGSRGSVIPL FKEQINKGGP ITITDFRMTR YFMTIPEASR LVIQAGALAR
GGEIFILDMG DPVKIIDLAK NMIKLSGYKE NEIKIIETGS RPGEKLYEEL LVNKKKNHKQ
VFDKIFIEDI RGSFPDEVLP FVDNLSMASK SLAEDIIRFA NASSH
//
