ID   F3ZJK1_9ACTN            Unreviewed;       390 AA.
AC   F3ZJK1;
DT   28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT   28-JUN-2011, sequence version 1.
DT   24-JAN-2024, entry version 39.
DE   SubName: Full=Putative cobalamin synthesis protein {ECO:0000313|EMBL:EGJ73086.1};
GN   ORFNames=STTU_0297 {ECO:0000313|EMBL:EGJ73086.1};
OS   Streptomyces sp. Tu6071.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=355249 {ECO:0000313|EMBL:EGJ73086.1};
RN   [1] {ECO:0000313|EMBL:EGJ73086.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Tu6071 {ECO:0000313|EMBL:EGJ73086.1};
RA   Erxleben A., Wunsch-Palasis J., Gruening B.A., Luzhetska M., Bechthold A.,
RA   Gunther S.;
RT   "Genome sequence of Streptomyces sp. Tu6071.";
RL   Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=GTP + H2O = GDP + H(+) + phosphate; Xref=Rhea:RHEA:19669,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:37565,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:58189;
CC         Evidence={ECO:0000256|ARBA:ARBA00001702};
CC       PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:19670;
CC         Evidence={ECO:0000256|ARBA:ARBA00001702};
CC   -!- SIMILARITY: Belongs to the SIMIBI class G3E GTPase family. ZNG1
CC       subfamily. {ECO:0000256|ARBA:ARBA00034320}.
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DR   EMBL; CM001165; EGJ73086.1; -; Genomic_DNA.
DR   AlphaFoldDB; F3ZJK1; -.
DR   HOGENOM; CLU_017452_2_0_11; -.
DR   Proteomes; UP000003955; Chromosome.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   CDD; cd03112; CobW-like; 1.
DR   Gene3D; 3.30.1220.10; CobW-like, C-terminal domain; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR036627; CobW-likC_sf.
DR   InterPro; IPR011629; CobW-like_C.
DR   InterPro; IPR003495; CobW/HypB/UreG_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR43603; COBW DOMAIN-CONTAINING PROTEIN DDB_G0274527; 1.
DR   PANTHER; PTHR43603:SF1; COBW DOMAIN-CONTAINING PROTEIN DDB_G0274527; 1.
DR   Pfam; PF02492; cobW; 1.
DR   Pfam; PF07683; CobW_C; 1.
DR   SMART; SM00833; CobW_C; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801}.
FT   DOMAIN          258..354
FT                   /note="CobW C-terminal"
FT                   /evidence="ECO:0000259|SMART:SM00833"
SQ   SEQUENCE   390 AA;  42477 MW;  E63658E64A0482B0 CRC64;
     MAAHALPVTV LSGFLGAGKT TLLQHVLDNR EGLRVAVIVN DMSEVNIDAA LVRGGPAALS
     RTEERLVEMT NGCICCTLRD DLLTEVDRLA REGRFDYLLI ESSGISEPLP VAATFAFARD
     DGASLGEVAR LDTMVTVVDA RNFLAELDTG DDLAERGLAA YGDDERTVSD LLVDQVEFAD
     VLVLNKLDLV GERDAERLRG VLARLNPRAR LLPAVRGRVP LRELLATGRF DLARAQEAPG
     WVRELNGEHV PETEEYGISS LVFRSPAAFQ PGRLWEFVTE GIDSGRYGRV LRSKGFFTLG
     GREDVTGLWS QAGAVARFEP SAVRDRDVPH AQEIVLIGTE LRADALRAAL TECLLGEGEP
     VPAEDPFPAW DTAEVCAEPY AHAPLVGRWR
//