ID F3ZKD0_9ACTN Unreviewed; 574 AA.
AC F3ZKD0;
DT 28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT 28-JUN-2011, sequence version 1.
DT 24-JAN-2024, entry version 45.
DE SubName: Full=Putative Beta-galactosidase {ECO:0000313|EMBL:EGJ78160.1};
GN ORFNames=STTU_5371 {ECO:0000313|EMBL:EGJ78160.1};
OS Streptomyces sp. Tu6071.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=355249 {ECO:0000313|EMBL:EGJ78160.1};
RN [1] {ECO:0000313|EMBL:EGJ78160.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Tu6071 {ECO:0000313|EMBL:EGJ78160.1};
RA Erxleben A., Wunsch-Palasis J., Gruening B.A., Luzhetska M., Bechthold A.,
RA Gunther S.;
RT "Genome sequence of Streptomyces sp. Tu6071.";
RL Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 35 family.
CC {ECO:0000256|ARBA:ARBA00009809}.
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DR EMBL; CM001165; EGJ78160.1; -; Genomic_DNA.
DR RefSeq; WP_007828395.1; NZ_CM001165.1.
DR AlphaFoldDB; F3ZKD0; -.
DR HOGENOM; CLU_007853_7_2_11; -.
DR Proteomes; UP000003955; Chromosome.
DR GO; GO:0004565; F:beta-galactosidase activity; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 2.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR InterPro; IPR026283; B-gal_1-like.
DR InterPro; IPR048912; BetaGal1-like_ABD1.
DR InterPro; IPR048913; BetaGal_gal-bd.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR031330; Gly_Hdrlase_35_cat.
DR InterPro; IPR019801; Glyco_hydro_35_CS.
DR InterPro; IPR001944; Glycoside_Hdrlase_35.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR23421:SF165; BETA-GALACTOSIDASE; 1.
DR PANTHER; PTHR23421; BETA-GALACTOSIDASE RELATED; 1.
DR Pfam; PF21317; BetaGal_ABD_1; 1.
DR Pfam; PF21467; BetaGal_gal-bd; 1.
DR Pfam; PF01301; Glyco_hydro_35; 1.
DR PIRSF; PIRSF006336; B-gal; 1.
DR PRINTS; PR00742; GLHYDRLASE35.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR PROSITE; PS01182; GLYCOSYL_HYDROL_F35; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801}.
FT DOMAIN 9..319
FT /note="Glycoside hydrolase 35 catalytic"
FT /evidence="ECO:0000259|Pfam:PF01301"
FT DOMAIN 370..467
FT /note="Beta-galactosidase 1-like first all-beta"
FT /evidence="ECO:0000259|Pfam:PF21317"
FT DOMAIN 496..549
FT /note="Beta-galactosidase galactose-binding"
FT /evidence="ECO:0000259|Pfam:PF21467"
FT ACT_SITE 150
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR006336-1"
FT ACT_SITE 226
FT /note="Nucleophile"
FT /evidence="ECO:0000256|PIRSR:PIRSR006336-1"
SQ SEQUENCE 574 AA; 62100 MW; 55F5B494CF378560 CRC64;
MFEIGERDFL VDGRPVRLLS GALHYFRVHE GQWAHRLGML RALGLNCVET YVPWNLHEPE
RGRYEDVAAL GRFLDAAAEA GLYAIVRPGP YICAEWENGG LPAWLRGPLR TRDAGFTEPV
AAWFRRLLPQ VVERQADRGG PVVMVQVENE YGSFGSDAVY LEWLTGLLRE VGVTVPLCTS
DGPEDWMLSG GTVPGVLATV NFGSGSEEAL ATLRRARPEG PLMVMEFWCG WFTHWGDKEV
ERRDAADAAA ELRAILDAGA SVNLYMAHGG SNGGWEGANR LGEWHDGAYT ATTTSYDYDA
PIDEAGRPTR KFHLMREVFA PYADGPLPEL PAAPPALGAE VSVRPAAWAP LGAVVDAVGG
GEREAAWAPS FEDLGVDRGL VRYRLRVPGP RAPRPLRLPE IRDLCEMYVD GVRVAPGTPV
GGGAEVELWV ESLGRVNYGP RVGESKGLPG GVLHATQYLH GVRATPLRLR DLDAALPALP
FTAPPAPGAR GLHLAVFTAA APGDAWLSLP GWGRGFVWLN GVCLGRYWSE GPQTELFVPG
PVLRAEGGNE LRVLELAGPE GEEAGEVRLR PVEG
//
