ID   F3ZLK1_9ACTN            Unreviewed;       296 AA.
AC   F3ZLK1;
DT   28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT   28-JUN-2011, sequence version 1.
DT   27-MAR-2024, entry version 49.
DE   SubName: Full=Putative transcriptional regulator {ECO:0000313|EMBL:EGJ78261.1};
GN   ORFNames=STTU_5474 {ECO:0000313|EMBL:EGJ78261.1};
OS   Streptomyces sp. Tu6071.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=355249 {ECO:0000313|EMBL:EGJ78261.1};
RN   [1] {ECO:0000313|EMBL:EGJ78261.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Tu6071 {ECO:0000313|EMBL:EGJ78261.1};
RA   Erxleben A., Wunsch-Palasis J., Gruening B.A., Luzhetska M., Bechthold A.,
RA   Gunther S.;
RT   "Genome sequence of Streptomyces sp. Tu6071.";
RL   Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CM001165; EGJ78261.1; -; Genomic_DNA.
DR   RefSeq; WP_007828583.1; NZ_CM001165.1.
DR   AlphaFoldDB; F3ZLK1; -.
DR   HOGENOM; CLU_993619_0_0_11; -.
DR   Proteomes; UP000003955; Chromosome.
DR   GO; GO:0016209; F:antioxidant activity; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   CDD; cd03017; PRX_BCP; 1.
DR   Gene3D; 3.40.30.10; Glutaredoxin; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR000866; AhpC/TSA.
DR   InterPro; IPR002577; HTH_HxlR.
DR   InterPro; IPR036249; Thioredoxin-like_sf.
DR   InterPro; IPR013766; Thioredoxin_domain.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR33204; TRANSCRIPTIONAL REGULATOR, MARR FAMILY; 1.
DR   PANTHER; PTHR33204:SF26; TRANSCRIPTIONAL REGULATORY PROTEIN; 1.
DR   Pfam; PF00578; AhpC-TSA; 1.
DR   Pfam; PF01638; HxlR; 1.
DR   SUPFAM; SSF52833; Thioredoxin-like; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS51118; HTH_HXLR; 1.
DR   PROSITE; PS51352; THIOREDOXIN_2; 1.
PE   4: Predicted;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT   DOMAIN          14..111
FT                   /note="HTH hxlR-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51118"
FT   DOMAIN          129..292
FT                   /note="Thioredoxin"
FT                   /evidence="ECO:0000259|PROSITE:PS51352"
SQ   SEQUENCE   296 AA;  32153 MW;  69420F64201709B1 CRC64;
     MPVPVRGGPE DENCAMAQAL GVVGDAWTLL LVRDVARGAH RFEDLRAGLG LSRKVLAERL
     RLLTGAGVLE KVPYQEHPPR HEYRLTARGR ALLPVLLALQ DWGDTWVLGE GETMATADGE
     SREAERVHGL RGAVLPRLLL PDATGTVLDP VADDAEFTVL YFFPAAFADP AAYPPGWAEI
     PGARGCTLES CTYRDEWPAF VERGTAVRGV STQRPDEQRA FAAGERLPFP LLSDAAGELA
     AALRLPTFST AGTRRLKRLT LLVDSERVVR EVWYPVPDVV ASVEAALAAV RERTDG
//