ID F4AZX6_DOKS4 Unreviewed; 422 AA.
AC F4AZX6;
DT 28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT 28-JUN-2011, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE SubName: Full=RNA-directed DNA polymerase (Reverse transcriptase) {ECO:0000313|EMBL:AEE20229.1};
GN OrderedLocusNames=Krodi_2249 {ECO:0000313|EMBL:AEE20229.1};
OS Dokdonia sp. (strain 4H-3-7-5) (Krokinobacter sp. (strain 4H-3-7-5)).
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Dokdonia.
OX NCBI_TaxID=983548 {ECO:0000313|EMBL:AEE20229.1, ECO:0000313|Proteomes:UP000008290};
RN [1] {ECO:0000313|EMBL:AEE20229.1, ECO:0000313|Proteomes:UP000008290}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=4H-3-7-5 {ECO:0000313|EMBL:AEE20229.1,
RC ECO:0000313|Proteomes:UP000008290};
RX PubMed=21725025; DOI=10.1128/JB.05518-11;
RA Klippel B., Lochner A., Bruce D.C., Walston Davenport K., Detter C.,
RA Goodwin L.A., Han J., Han S., Hauser L., Land M.L., Nolan M.,
RA Ovchinnikova G., Pennacchio L., Pitluck S., Tapia R., Woyke T.,
RA Wiebusch S., Basner A., Abe F., Horikoshi K., Keller M., Antranikian G.;
RT "Complete genome sequences of Krokinobacter sp. strain 4H-3-7-5 and
RT Lacinutrix sp. strain 5H-3-7-4, polysaccharide-degrading members of the
RT family Flavobacteriaceae.";
RL J. Bacteriol. 193:4545-4546(2011).
RN [2] {ECO:0000313|Proteomes:UP000008290}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=4H-3-7-5 {ECO:0000313|Proteomes:UP000008290};
RA Lucas S., Copeland A., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Davenport K., Detter J.C., Han C., Tapia R., Land M., Hauser L.,
RA Kyrpides N., Ivanova N., Ovchinnikova G., Pagani I., Piela B., Lochner A.,
RA Antranikian F.I., Woyke T.;
RT "Complete sequence of Krokinobacter diaphorus 4H-3-7-5.";
RL Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases.
RN [3]
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=4H-3-7-5;
RG US DOE Joint Genome Institute;
RA Lucas S., Copeland A., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Davenport K., Detter J.C., Han C., Tapia R., Land M., Hauser L.,
RA Kyrpides N., Ivanova N., Ovchinnikova G., Pagani I., Piela B., Lochner A.,
RA Antranikian F.I., Woyke T.;
RT "Complete sequence of Krokinobacter sp. 4H-3-7-5.";
RL Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the bacterial reverse transcriptase family.
CC {ECO:0000256|ARBA:ARBA00034120}.
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DR EMBL; CP002528; AEE20229.1; -; Genomic_DNA.
DR RefSeq; WP_013751736.1; NC_015496.1.
DR AlphaFoldDB; F4AZX6; -.
DR KEGG; kdi:Krodi_2249; -.
DR eggNOG; COG3344; Bacteria.
DR HOGENOM; CLU_013584_2_1_10; -.
DR OrthoDB; 9780724at2; -.
DR Proteomes; UP000008290; Chromosome.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0003964; F:RNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR GO; GO:0051607; P:defense response to virus; IEA:UniProtKB-KW.
DR CDD; cd01651; RT_G2_intron; 1.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR030931; Group_II_RT_mat.
DR InterPro; IPR013597; Mat_intron_G2.
DR InterPro; IPR000123; Reverse_transcriptase_msDNA.
DR InterPro; IPR000477; RT_dom.
DR NCBIfam; TIGR04416; group_II_RT_mat; 1.
DR PANTHER; PTHR34047:SF2; NUCLEAR INTRON MATURASE 1, MITOCHONDRIAL; 1.
DR PANTHER; PTHR34047; NUCLEAR INTRON MATURASE 1, MITOCHONDRIAL-RELATED; 1.
DR Pfam; PF08388; GIIM; 1.
DR Pfam; PF00078; RVT_1; 1.
DR PRINTS; PR00866; RNADNAPOLMS.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR PROSITE; PS50878; RT_POL; 1.
PE 3: Inferred from homology;
KW Antiviral defense {ECO:0000256|ARBA:ARBA00023118};
KW Nucleotidyltransferase {ECO:0000313|EMBL:AEE20229.1};
KW RNA-directed DNA polymerase {ECO:0000313|EMBL:AEE20229.1};
KW Transferase {ECO:0000313|EMBL:AEE20229.1}.
FT DOMAIN 46..272
FT /note="Reverse transcriptase"
FT /evidence="ECO:0000259|PROSITE:PS50878"
SQ SEQUENCE 422 AA; 49405 MW; BCFF33B27E88D367 CRC64;
MIKQVTSKKN LNEAYARVYR NKGSAGVDKV HIKELKSILQ IHGKQYISHI ERKRYQVSPI
LGVEIPKSNG KKRLLGIPTV VDRVFQQALH QVLQPLFEPD FQKHSYGFRP QRNAHQATAQ
SLLNINAGFQ DIVDIDLKSF FDEVSHCILL ELIYKKVQCK ATMRLLRSFL RAPILINGRL
QKRRKGVPQG SPLSPLLSNI LLNELDKELE QRGHRYVRYA DDFSIYVKSK EAAKRVGNSI
YKYLRDHLQL PINRVKSGVR RPLDFQVLGF GFVPTYKKGE KGKYQLVVTR SKWQDFKSKL
KYLTKKTIPA SFDERIKRIN LLIRGWINYF KPASIQSKLK KLEEWLRNRL RYCIWHHWKK
PERKRKNLIR LGVNLDHAYA WSRTRMGGWA VAQSPILGTT ITIKRLKMRG YVSLIEYYNR
AV
//
