ID   F4BY50_METSG            Unreviewed;       970 AA.
AC   F4BY50;
DT   28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT   28-JUN-2011, sequence version 1.
DT   27-MAR-2024, entry version 68.
DE   SubName: Full=ATP-dependent RNA helicase, putative {ECO:0000313|EMBL:AEB68802.1};
GN   OrderedLocusNames=MCON_2326 {ECO:0000313|EMBL:AEB68802.1};
OS   Methanothrix soehngenii (strain ATCC 5969 / DSM 3671 / JCM 10134 / NBRC
OS   103675 / OCM 69 / GP-6) (Methanosaeta concilii).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC   Methanotrichales; Methanotrichaceae; Methanothrix.
OX   NCBI_TaxID=990316 {ECO:0000313|EMBL:AEB68802.1, ECO:0000313|Proteomes:UP000007807};
RN   [1] {ECO:0000313|EMBL:AEB68802.1, ECO:0000313|Proteomes:UP000007807}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 5969 / DSM 3671 / JCM 10134 / NBRC 103675 / OCM 69 / GP-6
RC   {ECO:0000313|Proteomes:UP000007807};
RX   PubMed=21571998; DOI=10.1128/JB.05031-11;
RA   Barber R.D., Zhang L., Harnack M., Olson M.V., Kaul R., Ingram-Smith C.,
RA   Smith K.S.;
RT   "Complete genome sequence of Methanosaeta concilii, a specialist in
RT   aceticlastic methanogenesis.";
RL   J. Bacteriol. 193:3668-3669(2011).
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP002565; AEB68802.1; -; Genomic_DNA.
DR   RefSeq; WP_013719836.1; NC_015416.1.
DR   AlphaFoldDB; F4BY50; -.
DR   STRING; 990316.MCON_2326; -.
DR   GeneID; 10461749; -.
DR   KEGG; mcj:MCON_2326; -.
DR   HOGENOM; CLU_002025_0_0_2; -.
DR   InParanoid; F4BY50; -.
DR   OrthoDB; 33870at2157; -.
DR   Proteomes; UP000007807; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016818; F:hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; IEA:InterPro.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR013701; DEAD/DEAH_assoc.
DR   InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR017170; Lhr-like_ATP-dep_RNA_helic_prd.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR47962:SF5; ATP-DEPENDENT HELICASE LHR-RELATED; 1.
DR   PANTHER; PTHR47962; ATP-DEPENDENT HELICASE LHR-RELATED-RELATED; 1.
DR   Pfam; PF00270; DEAD; 1.
DR   Pfam; PF08494; DEAD_assoc; 1.
DR   Pfam; PF00271; Helicase_C; 1.
DR   PIRSF; PIRSF037307; Lhr-like_helic_prd; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW   DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW   Helicase {ECO:0000313|EMBL:AEB68802.1};
KW   Hydrolase {ECO:0000313|EMBL:AEB68802.1};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007807}.
FT   DOMAIN          31..246
FT                   /note="Helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51192"
FT   DOMAIN          285..432
FT                   /note="Helicase C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51194"
FT   REGION          64..102
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   970 AA;  108410 MW;  3B7BC475835AB5DC CRC64;
     MSAFDHLHHR IRAILQEQGI IEPTLPQEKA IPTILEGENV LLIAPTGTGK TEAASLPIFH
     QILSGEGKSN NTPKHGREKK KASRTMDSDG MQSSAMESGG MDSNGIKGIR AVYITPLRAL
     NRDMLRRFHD WGESLGISVA VRHGDTSQSD RRRQSLSPPD ILITTPETLQ VMLTGKRLRL
     NLSTVRTVVV DEVHEMASSK RGSQLSVLLE RLVEIAGDFQ RIGLSATVGS PETVARLLVG
     TNRGYRIVCA DVERASNYQV VSPQPKGGDY SLASTLECDP RLAAQIRWIR DEVRDKKCLI
     FVNTRQAAEV LGSRFRQLGE PIGVHHGSLS REARVEAEEA FKAGELQGLI CTSSMELGID
     IGDVDHVIQY SSPREVSRML QRVGRAGHKI GLVSSGSIIA TCADDVAEAC AIARRAADSK
     LEEIKIHEKP TDVLANQIVG LEIDFGDISL QRVHQIVSRA YPFRDLTVEE LEGVVSQMEE
     HRLVRREGGI LQRTRKAREY YIENLSMIPD EKRYNVYDIV GRRSVGTLDE AFVVGFAQPG
     ATFVTKGEIW EITEIAEEEI KVVPIQRSGE IPSWTGEEIP VPFDVAQEVG RIRREISEMF
     ESGKGAEDAE EWLQSCYPVE DEAARELVDL IMRQREKNHP VPNESLVVVE GGGEGAIINC
     CFGHKTNDTL GRVITSILSA RFGSSVALQI DPYRIELTLP KALLAEEIEK LIEDLDPDYV
     QPILEMTLKN TSLLRWKMIH VARKFGALSR DVDYQRVSMA KLLAVFEGTP MYREALREIY
     HDRLDIERTR MVLVRIRDGS MAMTTSSLSP IGTSGRGGGK DVTSPENADA AVIKLLKNRI
     MKDRVLLFCV NCKKWKSMRQ VERVPDRPEC PLCGSRMVAA LKPWEEDEIK VVRKRDKKTS
     DEKRRTKRVF RNANLVLSYG KTAAIALASR GLGPETAARV IGKLQKDEIE FYRDILKAEK
     EYARTKRFWG
//