ID   F4C652_SPHS2            Unreviewed;       369 AA.
AC   F4C652;
DT   28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT   28-JUN-2011, sequence version 1.
DT   27-MAR-2024, entry version 47.
DE   SubName: Full=Putative adenylate/guanylate cyclase {ECO:0000313|EMBL:ADZ80794.1};
DE            EC=4.6.1.1 {ECO:0000313|EMBL:ADZ80794.1};
GN   OrderedLocusNames=Sph21_4271 {ECO:0000313|EMBL:ADZ80794.1};
OS   Sphingobacterium sp. (strain 21).
OC   Bacteria; Bacteroidota; Sphingobacteriia; Sphingobacteriales;
OC   Sphingobacteriaceae; Sphingobacterium.
OX   NCBI_TaxID=743722 {ECO:0000313|EMBL:ADZ80794.1};
RN   [1] {ECO:0000313|EMBL:ADZ80794.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=21 {ECO:0000313|EMBL:ADZ80794.1};
RG   US DOE Joint Genome Institute;
RA   Lucas S., Copeland A., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA   Davenport K., Detter J.C., Han C., Tapia R., Land M., Hauser L.,
RA   Kyrpides N., Ivanova N., Ovchinnikova G., Pagani I., Siebers A.K.,
RA   Allgaier M., Thelen M.P., Hugenholtz P., Woyke T.;
RT   "Complete sequence of Sphingobacterium sp. 21.";
RL   Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CP002584; ADZ80794.1; -; Genomic_DNA.
DR   AlphaFoldDB; F4C652; -.
DR   STRING; 743722.Sph21_4271; -.
DR   KEGG; shg:Sph21_4271; -.
DR   PATRIC; fig|743722.3.peg.4551; -.
DR   eggNOG; COG2114; Bacteria.
DR   HOGENOM; CLU_055425_1_0_10; -.
DR   OrthoDB; 9768499at2; -.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004016; F:adenylate cyclase activity; IEA:UniProtKB-EC.
DR   GO; GO:0009190; P:cyclic nucleotide biosynthetic process; IEA:InterPro.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   CDD; cd07302; CHD; 1.
DR   Gene3D; 3.30.70.1230; Nucleotide cyclase; 1.
DR   InterPro; IPR001054; A/G_cyclase.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   Pfam; PF00211; Guanylate_cyc; 1.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   PROSITE; PS50125; GUANYLATE_CYCLASE_2; 1.
PE   4: Predicted;
KW   Lyase {ECO:0000313|EMBL:ADZ80794.1}; Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..32
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        52..73
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        85..110
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          182..311
FT                   /note="Guanylate cyclase"
FT                   /evidence="ECO:0000259|PROSITE:PS50125"
SQ   SEQUENCE   369 AA;  41304 MW;  1DEEF4AFD715C420 CRC64;
     MKRGTFLKLR QLGLIIIIWM FIGFIIAIYD HLVLHTQVSL GTTANYSFFI SVLRNIGAGL
     IGALLGGSIL VFYINEKFRD KPYGYTILIV IICFVLIVGI ITLVMGLTIV PYQLKRPLSD
     PTTRQAVVSF MTDSYPLKNG LVWAFIVALT QFLLQVSSKF GHETFLHILT GKYNTPKAEK
     RIFMFLDLNA STTIAERLGN ERYHSLLKDF FADITNPILE NKGNIYQYVG DEVVVAWSYK
     DGLEKSHCLR CFFDIKMTIE DKKDKYEQLY GLVPTFKAGI HSGNVIAGEI GVVKRDITYS
     GDVLNTTSRI LGKCGEFKEE VIISADLLSL LNSAKEYSSK LLGSIRLRGK EREVAILALL
     PNSIDSAGS
//