ID   F4C9V4_SPHS2            Unreviewed;       378 AA.
AC   F4C9V4;
DT   28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT   28-JUN-2011, sequence version 1.
DT   27-MAR-2024, entry version 44.
DE   SubName: Full=Alcohol dehydrogenase {ECO:0000313|EMBL:ADZ77244.1};
DE            EC=1.1.1.1 {ECO:0000313|EMBL:ADZ77244.1};
GN   OrderedLocusNames=Sph21_0665 {ECO:0000313|EMBL:ADZ77244.1};
OS   Sphingobacterium sp. (strain 21).
OC   Bacteria; Bacteroidota; Sphingobacteriia; Sphingobacteriales;
OC   Sphingobacteriaceae; Sphingobacterium.
OX   NCBI_TaxID=743722 {ECO:0000313|EMBL:ADZ77244.1};
RN   [1] {ECO:0000313|EMBL:ADZ77244.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=21 {ECO:0000313|EMBL:ADZ77244.1};
RG   US DOE Joint Genome Institute;
RA   Lucas S., Copeland A., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA   Davenport K., Detter J.C., Han C., Tapia R., Land M., Hauser L.,
RA   Kyrpides N., Ivanova N., Ovchinnikova G., Pagani I., Siebers A.K.,
RA   Allgaier M., Thelen M.P., Hugenholtz P., Woyke T.;
RT   "Complete sequence of Sphingobacterium sp. 21.";
RL   Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the iron-containing alcohol dehydrogenase
CC       family. {ECO:0000256|ARBA:ARBA00007358}.
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DR   EMBL; CP002584; ADZ77244.1; -; Genomic_DNA.
DR   AlphaFoldDB; F4C9V4; -.
DR   STRING; 743722.Sph21_0665; -.
DR   KEGG; shg:Sph21_0665; -.
DR   PATRIC; fig|743722.3.peg.716; -.
DR   eggNOG; COG1454; Bacteria.
DR   HOGENOM; CLU_007207_0_0_10; -.
DR   OrthoDB; 9801156at2; -.
DR   GO; GO:0004022; F:alcohol dehydrogenase (NAD+) activity; IEA:UniProtKB-EC.
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   CDD; cd14861; Fe-ADH-like; 1.
DR   Gene3D; 3.40.50.1970; -; 1.
DR   Gene3D; 1.20.1090.10; Dehydroquinate synthase-like - alpha domain; 1.
DR   InterPro; IPR001670; ADH_Fe/GldA.
DR   InterPro; IPR018211; ADH_Fe_CS.
DR   InterPro; IPR039697; Alcohol_dehydrogenase_Fe.
DR   PANTHER; PTHR11496; ALCOHOL DEHYDROGENASE; 1.
DR   PANTHER; PTHR11496:SF102; ALCOHOL DEHYDROGENASE 4; 1.
DR   Pfam; PF00465; Fe-ADH; 1.
DR   SUPFAM; SSF56796; Dehydroquinate synthase-like; 1.
DR   PROSITE; PS00913; ADH_IRON_1; 1.
DR   PROSITE; PS00060; ADH_IRON_2; 1.
PE   3: Inferred from homology;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW   ECO:0000313|EMBL:ADZ77244.1}.
FT   DOMAIN          8..369
FT                   /note="Alcohol dehydrogenase iron-type/glycerol
FT                   dehydrogenase GldA"
FT                   /evidence="ECO:0000259|Pfam:PF00465"
SQ   SEQUENCE   378 AA;  41579 MW;  2CC37200063A1814 CRC64;
     MIYQFNIPTT IRFGCGAIKE LPAYLIEQGL KRPLLVTDPT IAQLDFFAEI VRDLNLKGIH
     LEVFSDIHKN PVKSDVYKGT DIWDQTDRDS IVGIGGGAAL DIARAIVLRV NHRDDLFKYD
     DLVGGDVYVT NSVPHFITVP TTAGTGSEVG RSAIIADDET HQKKILFSPK LMAKIVFADP
     LLTMGLPPHI TAATGMDALT HNMEAFLAKN PNPICDGIAL EGMHLIAKSL EQAVLRPNEQ
     VRSNMLVASM MGAIAFQKGL GVVHSLAHPL SSLLDTHHGL ANAVNIPYGM AFNIAGNEDK
     FKRIAQALQL REETGEGVIK YLFELNEHIG IPKKLRDIGV KEEHIEILAD LAIADFAHPN
     NPKPVSREDF KRLYQQAF
//