ID   F4CAZ1_SPHS2            Unreviewed;       830 AA.
AC   F4CAZ1;
DT   28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT   28-JUN-2011, sequence version 1.
DT   27-MAR-2024, entry version 60.
DE   SubName: Full=ATP-dependent helicase HrpB {ECO:0000313|EMBL:ADZ78558.1};
GN   OrderedLocusNames=Sph21_1998 {ECO:0000313|EMBL:ADZ78558.1};
OS   Sphingobacterium sp. (strain 21).
OC   Bacteria; Bacteroidota; Sphingobacteriia; Sphingobacteriales;
OC   Sphingobacteriaceae; Sphingobacterium.
OX   NCBI_TaxID=743722 {ECO:0000313|EMBL:ADZ78558.1};
RN   [1] {ECO:0000313|EMBL:ADZ78558.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=21 {ECO:0000313|EMBL:ADZ78558.1};
RG   US DOE Joint Genome Institute;
RA   Lucas S., Copeland A., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA   Davenport K., Detter J.C., Han C., Tapia R., Land M., Hauser L.,
RA   Kyrpides N., Ivanova N., Ovchinnikova G., Pagani I., Siebers A.K.,
RA   Allgaier M., Thelen M.P., Hugenholtz P., Woyke T.;
RT   "Complete sequence of Sphingobacterium sp. 21.";
RL   Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CP002584; ADZ78558.1; -; Genomic_DNA.
DR   AlphaFoldDB; F4CAZ1; -.
DR   STRING; 743722.Sph21_1998; -.
DR   KEGG; shg:Sph21_1998; -.
DR   PATRIC; fig|743722.3.peg.2133; -.
DR   eggNOG; COG1643; Bacteria.
DR   HOGENOM; CLU_001832_5_6_10; -.
DR   OrthoDB; 9808833at2; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   CDD; cd17990; DEXHc_HrpB; 1.
DR   CDD; cd18791; SF2_C_RHA; 1.
DR   Gene3D; 1.20.120.1080; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR   InterPro; IPR007502; Helicase-assoc_dom.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR010225; HrpB.
DR   InterPro; IPR049614; HrpB_DEXH.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR013689; RNA_helicase_ATP-dep_HrpB_C.
DR   NCBIfam; TIGR01970; DEAH_box_HrpB; 1.
DR   PANTHER; PTHR43519; ATP-DEPENDENT RNA HELICASE HRPB; 1.
DR   PANTHER; PTHR43519:SF1; ATP-DEPENDENT RNA HELICASE HRPB; 1.
DR   Pfam; PF00270; DEAD; 1.
DR   Pfam; PF00271; Helicase_C; 1.
DR   Pfam; PF08482; HrpB_C; 1.
DR   PIRSF; PIRSF005496; ATP_hel_hrpB; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM00847; HA2; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:ADZ78558.1};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT   DOMAIN          20..184
FT                   /note="Helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51192"
FT   DOMAIN          210..373
FT                   /note="Helicase C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51194"
SQ   SEQUENCE   830 AA;  93846 MW;  B9C948ED47984510 CRC64;
     MLSILEEPQL PIQQILSKVQ DSLKKHPNLL VSASPGAGKS TLLPLRLLDE PWLKGKKILL
     LEPRRLAAIA IAGRMASLLD EDIGKTIGYR IRFEHKVSNS TRIEVVTEGI LTRMIQDDNA
     LEAFGLIIFD EFHERSIHAD TALTLCLETQ EILRPDLRLL VMSATLDLPN LAQLLKAPTI
     ECPSRTHPID IIYTGEQNLE SLPSLCVQTI LRALHETIGD ILVFLPGQAA INRCKDLLKI
     KKTTAIIHCL YGQLSIAAQQ RAILPDEKGG RKVILATSIA ETSLTIEGVR VVIDSGFTRQ
     AIFDAKTNLS SLQTVSISLD SAIQRSGRAG RLGPGTCYRM WSKTQEAKMK TYRNPEIIDA
     DLMPLTLELF KWGISSVDQL KWLTPPPLER FLQAQKILTR IEAIMDGKIS AHGKMIHRLP
     CHPRLAHMLS AAASEKLHLH LATDIAALLE ERDPLSNTIE TDLNLRIEGL RRARKNHTYY
     QSFSKVIKIA AYYRRLFGIE ENNDDPDPYV SGCLVAYAYP DRIARKIEQG SNRFFMANGR
     KATLLLSDSL CNEDFLVIAH IDFRGGEGKV FLAAPLKKED VFPLTTHDTN IQWDSNNGAF
     LAREEWKIDN LIVQTRPLQQ IPPDLATEVL LKVIKKEGLH LLNYTTEVEQ WQNRVMSLKF
     WDQKAYWPKA DTDSLLNCVE EWLAPYLTKC RKAEDLKKLD LISILVHWLP FELQRKLEKL
     APTKLTVPSG SQIRLRYLPN GESPILAVRL QEVFGLLETP TINDGKTPVS LHLLSPGFKL
     VQITADLKSF WSNAYFEVRK ELKRRYPKHA WPENPIDVPA VRGVNKRMYP
//