ID F4CVJ9_PSEUX Unreviewed; 418 AA.
AC F4CVJ9;
DT 28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT 28-JUN-2011, sequence version 1.
DT 27-MAR-2024, entry version 54.
DE SubName: Full=Sterol 3-beta-glucosyltransferase {ECO:0000313|EMBL:AEA24174.1};
DE EC=2.4.1.173 {ECO:0000313|EMBL:AEA24174.1};
GN OrderedLocusNames=Psed_1943 {ECO:0000313|EMBL:AEA24174.1};
OS Pseudonocardia dioxanivorans (strain ATCC 55486 / DSM 44775 / JCM 13855 /
OS CB1190).
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Pseudonocardia.
OX NCBI_TaxID=675635 {ECO:0000313|EMBL:AEA24174.1, ECO:0000313|Proteomes:UP000007809};
RN [1] {ECO:0000313|EMBL:AEA24174.1, ECO:0000313|Proteomes:UP000007809}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 55486 / DSM 44775 / JCM 13855 / CB1190
RC {ECO:0000313|Proteomes:UP000007809};
RX PubMed=21725009; DOI=10.1128/JB.00415-11;
RA Sales C.M., Mahendra S., Grostern A., Parales R.E., Goodwin L.A., Woyke T.,
RA Nolan M., Lapidus A., Chertkov O., Ovchinnikova G., Sczyrba A.,
RA Alvarez-Cohen L.;
RT "Genome sequence of the 1,4-dioxane-degrading Pseudonocardia dioxanivorans
RT strain CB1190.";
RL J. Bacteriol. 193:4549-4550(2011).
CC -!- PATHWAY: Antibiotic biosynthesis; vancomycin biosynthesis.
CC {ECO:0000256|ARBA:ARBA00004660}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 28 family.
CC {ECO:0000256|ARBA:ARBA00006962}.
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DR EMBL; CP002593; AEA24174.1; -; Genomic_DNA.
DR RefSeq; WP_013674105.1; NC_015312.1.
DR AlphaFoldDB; F4CVJ9; -.
DR STRING; 675635.Psed_1943; -.
DR KEGG; pdx:Psed_1943; -.
DR eggNOG; COG1819; Bacteria.
DR HOGENOM; CLU_000537_8_0_11; -.
DR OrthoDB; 3253247at2; -.
DR UniPathway; UPA00162; -.
DR Proteomes; UP000007809; Chromosome.
DR GO; GO:0102203; F:brassicasterol glucosyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0102205; F:cholesterol alpha-glucosyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0102202; F:soladodine glucosyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0016906; F:sterol 3-beta-glucosyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR GO; GO:0030259; P:lipid glycosylation; IEA:InterPro.
DR GO; GO:0033072; P:vancomycin biosynthetic process; IEA:UniProtKB-UniPathway.
DR CDD; cd03784; GT1_Gtf-like; 1.
DR Gene3D; 3.40.50.2000; Glycogen Phosphorylase B; 2.
DR InterPro; IPR010610; EryCIII-like_C.
DR InterPro; IPR004276; GlycoTrans_28_N.
DR InterPro; IPR002213; UDP_glucos_trans.
DR PANTHER; PTHR48050; STEROL 3-BETA-GLUCOSYLTRANSFERASE; 1.
DR PANTHER; PTHR48050:SF13; UDP-GLUCURONOSYLTRANSFERASE; 1.
DR Pfam; PF06722; EryCIII-like_C; 1.
DR Pfam; PF03033; Glyco_transf_28; 1.
DR SUPFAM; SSF53756; UDP-Glycosyltransferase/glycogen phosphorylase; 1.
PE 3: Inferred from homology;
KW Antibiotic biosynthesis {ECO:0000256|ARBA:ARBA00023194};
KW Glycosyltransferase {ECO:0000313|EMBL:AEA24174.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000007809};
KW Transferase {ECO:0000313|EMBL:AEA24174.1}.
FT DOMAIN 3..141
FT /note="Glycosyltransferase family 28 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF03033"
FT DOMAIN 299..405
FT /note="Erythromycin biosynthesis protein CIII-like C-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF06722"
FT REGION 181..201
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 185..200
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 418 AA; 43490 MW; A1E0F1D639461F11 CRC64;
MRITLLAVGS RGDVEPFVVL GVRLRRAGHG VRFATHDEFA STVGAAGLEF ATLPGNPRAV
LASPEGKRML ATRNPVALTR RMAAIVGPAL DEAYPAAVDA CRDADLVVYA TLAAIGPNVA
DLYGVPAVAA HLQPQTPTRA FGPTGSPGVR DVPAALRHAT WALADRLLWK AFLPTIAAQR
RAQGSPPLPP GPPSHWPPGT RPPTLYGFSR VVVPVPPDWP PDVHVTGYWM APPDPHHVPP
RELAAFLDAG PAPVYIGFGS MPDRDAGQLV DIALAAARRA RTRMVLAAGW AGLAPGHPSD
DVLVVGDVPH RWLFERVAAV VHHGGAGTTA AGLRAGRPSV VVPFFSDQFF WGRRVAALGA
GPPPIAREKL TAAALTEALR AALQPGPAAA AAAVGARIAD EDGPACAVAV LERIGGRA
//
