ID   F4H6I3_CELFA            Unreviewed;       536 AA.
AC   F4H6I3;
DT   28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT   28-JUN-2011, sequence version 1.
DT   24-JAN-2024, entry version 51.
DE   RecName: Full=Endoglucanase {ECO:0000256|RuleBase:RU361166};
DE            EC=3.2.1.4 {ECO:0000256|RuleBase:RU361166};
GN   OrderedLocusNames=Celf_1481 {ECO:0000313|EMBL:AEE45616.1};
OS   Cellulomonas fimi (strain ATCC 484 / DSM 20113 / JCM 1341 / NBRC 15513 /
OS   NCIMB 8980 / NCTC 7547).
OC   Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Cellulomonadaceae;
OC   Cellulomonas.
OX   NCBI_TaxID=590998 {ECO:0000313|EMBL:AEE45616.1, ECO:0000313|Proteomes:UP000008460};
RN   [1] {ECO:0000313|EMBL:AEE45616.1, ECO:0000313|Proteomes:UP000008460}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 484 / DSM 20113 / JCM 1341 / NBRC 15513 / NCIMB 8980 /
RC   NCTC 7547 {ECO:0000313|Proteomes:UP000008460};
RG   US DOE Joint Genome Institute;
RA   Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA   Peters L., Chertkov O., Detter J.C., Han C., Tapia R., Land M., Hauser L.,
RA   Kyrpides N., Ivanova N., Ovchinnikova G., Pagani I., Mead D., Brumm P.,
RA   Woyke T.;
RT   "Complete sequence of Cellulomonas fimi ATCC 484.";
RL   Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=Endohydrolysis of (1->4)-beta-D-glucosidic linkages in
CC         cellulose, lichenin and cereal beta-D-glucans.; EC=3.2.1.4;
CC         Evidence={ECO:0000256|RuleBase:RU361166};
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 9 (cellulase E) family.
CC       {ECO:0000256|PROSITE-ProRule:PRU10060, ECO:0000256|RuleBase:RU361166}.
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DR   EMBL; CP002666; AEE45616.1; -; Genomic_DNA.
DR   RefSeq; WP_013770642.1; NC_015514.1.
DR   AlphaFoldDB; F4H6I3; -.
DR   STRING; 590998.Celf_1481; -.
DR   KEGG; cfi:Celf_1481; -.
DR   eggNOG; COG5297; Bacteria.
DR   HOGENOM; CLU_006010_2_1_11; -.
DR   Proteomes; UP000008460; Chromosome.
DR   GO; GO:0008810; F:cellulase activity; IEA:UniProtKB-EC.
DR   GO; GO:0030245; P:cellulose catabolic process; IEA:UniProtKB-KW.
DR   Gene3D; 1.50.10.10; -; 1.
DR   InterPro; IPR008928; 6-hairpin_glycosidase_sf.
DR   InterPro; IPR012341; 6hp_glycosidase-like_sf.
DR   InterPro; IPR001701; Glyco_hydro_9.
DR   InterPro; IPR033126; Glyco_hydro_9_Asp/Glu_AS.
DR   PANTHER; PTHR22298; ENDO-1,4-BETA-GLUCANASE; 1.
DR   PANTHER; PTHR22298:SF29; ENDOGLUCANASE; 1.
DR   Pfam; PF00759; Glyco_hydro_9; 1.
DR   SUPFAM; SSF48208; Six-hairpin glycosidases; 1.
DR   PROSITE; PS00698; GH9_3; 1.
PE   3: Inferred from homology;
KW   Carbohydrate metabolism {ECO:0000256|ARBA:ARBA00023277,
KW   ECO:0000256|PROSITE-ProRule:PRU10060};
KW   Cellulose degradation {ECO:0000256|RuleBase:RU361166};
KW   Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000256|PROSITE-
KW   ProRule:PRU10060};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW   ProRule:PRU10060};
KW   Polysaccharide degradation {ECO:0000256|ARBA:ARBA00023326,
KW   ECO:0000256|PROSITE-ProRule:PRU10060};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008460}.
FT   DOMAIN          39..518
FT                   /note="Glycoside hydrolase family 9"
FT                   /evidence="ECO:0000259|Pfam:PF00759"
FT   REGION          458..477
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   ACT_SITE        497
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU10060"
FT   ACT_SITE        506
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU10060"
SQ   SEQUENCE   536 AA;  56430 MW;  DE19B21CD2B9C6BA CRC64;
     MHTLHLDDVH EPGAGYVLEA DGATSDPFAI GGDLWDGLRV DSLVVFYGQR SGIPIEEDLL
     GAGYGRAAGH VDVAPNGGDG DVACLPAGHA TTAAGVDLYE GWTGGYALDV TGGWYDAGDQ
     GKYVVNGGIA VAQLLGLYER ALRTGTAGAL GDGSLRVPES GDGVPDVLSE ARWELEWMLR
     MVVPEGEPLA GLVHHKVSDE RWVPLPMLPA DDPQPRFLHR PSTAATLNLA AVAAQGSRLF
     APHDAAFADR LLAAARAAYD AAQAHPVLLA PDTNTLENAG SGPYDDTDVD DDRLWAATEL
     YLSTGEDRYA ADLRANPYRL GGTAPAFRPE GFDWNHVAAW ARLQLATVDS ALPERALVRA
     SVVDAADALV EAQATQPFGH PYVPTSGRYD WGSNGLLLNN LAVLAAAHEI TGDDRYRDAV
     LGGVDYVFGR NALGVSYVTG YGTRDVRNQH SRWYAHQLDP ALPHPPRGTV SGGPNSDCPD
     PVSAALAGSP AQCCFVDDVG AYGVNEMTIN WNSALAWVAA YLAGLGDGRP SPAAEG
//