ID F4HCU1_GALAU Unreviewed; 369 AA.
AC F4HCU1;
DT 28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT 28-JUN-2011, sequence version 1.
DT 27-MAR-2024, entry version 58.
DE RecName: Full=Citrate synthase {ECO:0000256|PIRNR:PIRNR001369};
GN OrderedLocusNames=UMN179_00523 {ECO:0000313|EMBL:AEC16559.1};
OS Gallibacterium anatis (strain UMN179) (Pasteurella anatis).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Pasteurellales;
OC Pasteurellaceae; Gallibacterium.
OX NCBI_TaxID=1005058 {ECO:0000313|EMBL:AEC16559.1, ECO:0000313|Proteomes:UP000006908};
RN [1] {ECO:0000313|EMBL:AEC16559.1, ECO:0000313|Proteomes:UP000006908}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UMN179 {ECO:0000313|EMBL:AEC16559.1,
RC ECO:0000313|Proteomes:UP000006908};
RX PubMed=21602325; DOI=10.1128/JB.05177-11;
RA Johnson T.J., Fernandez-Alarcon C., Bojesen A.M., Nolan L.K., Trampel D.W.,
RA Seemann T.;
RT "Complete genome sequence of Gallibacterium anatis strain UMN179, isolated
RT from a laying hen with peritonitis.";
RL J. Bacteriol. 193:3676-3677(2011).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=acetyl-CoA + H2O + oxaloacetate = citrate + CoA + H(+);
CC Xref=Rhea:RHEA:16845, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:16452, ChEBI:CHEBI:16947, ChEBI:CHEBI:57287,
CC ChEBI:CHEBI:57288; EC=2.3.3.16;
CC Evidence={ECO:0000256|ARBA:ARBA00000308};
CC -!- PATHWAY: Carbohydrate metabolism; tricarboxylic acid cycle; isocitrate
CC from oxaloacetate: step 1/2. {ECO:0000256|ARBA:ARBA00004751}.
CC -!- SIMILARITY: Belongs to the citrate synthase family.
CC {ECO:0000256|ARBA:ARBA00010566, ECO:0000256|PIRNR:PIRNR001369,
CC ECO:0000256|RuleBase:RU003406}.
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DR EMBL; CP002667; AEC16559.1; -; Genomic_DNA.
DR RefSeq; WP_013745346.1; NC_015460.1.
DR AlphaFoldDB; F4HCU1; -.
DR SMR; F4HCU1; -.
DR STRING; 1005058.UMN179_00523; -.
DR GeneID; 77264420; -.
DR KEGG; gan:UMN179_00523; -.
DR PATRIC; fig|1005058.3.peg.512; -.
DR eggNOG; COG0372; Bacteria.
DR HOGENOM; CLU_025068_2_1_6; -.
DR UniPathway; UPA00223; UER00717.
DR Proteomes; UP000006908; Chromosome.
DR GO; GO:0036440; F:citrate synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-UniPathway.
DR Gene3D; 1.10.580.10; Citrate Synthase, domain 1; 1.
DR Gene3D; 1.10.230.10; Cytochrome P450-Terp, domain 2; 1.
DR InterPro; IPR016142; Citrate_synth-like_lrg_a-sub.
DR InterPro; IPR016143; Citrate_synth-like_sm_a-sub.
DR InterPro; IPR002020; Citrate_synthase.
DR InterPro; IPR019810; Citrate_synthase_AS.
DR InterPro; IPR024176; Citrate_synthase_bac-typ.
DR InterPro; IPR036969; Citrate_synthase_sf.
DR PANTHER; PTHR11739; CITRATE SYNTHASE; 1.
DR PANTHER; PTHR11739:SF25; CITRATE SYNTHASE-RELATED PROTEIN DDB_G0287281; 1.
DR Pfam; PF00285; Citrate_synt; 1.
DR PIRSF; PIRSF001369; Citrate_synth; 1.
DR PRINTS; PR00143; CITRTSNTHASE.
DR SUPFAM; SSF48256; Citrate synthase; 1.
DR PROSITE; PS00480; CITRATE_SYNTHASE; 1.
PE 3: Inferred from homology;
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|PIRNR:PIRNR001369}.
FT ACT_SITE 253
FT /evidence="ECO:0000256|PIRSR:PIRSR001369-1"
FT ACT_SITE 305
FT /evidence="ECO:0000256|PIRSR:PIRSR001369-1"
SQ SEQUENCE 369 AA; 41052 MW; 5D581DA4F8080DC3 CRC64;
MSGLAGITAG SSAICTCGLG NGLNYRGYAI QDLALKADFE EVAYLLLVGE LPNQKQLNDF
RRKIIAAREL PIAVKNVLKS IPASSHPMDV MRTATSALGC VEPEKEDFSD QLAKAIRLLG
ALPSFLIYWH HWHKHGKEID LISDETTMAG YILERLKLKK PLDVEVKAMN AMLTLYAEHE
FNASTFANRI AASTLSDIYS CITAGIAALK GRLHGGANEV AVKFVLQFDS VEQALKSVDE
LFARKEKIMG FGHRVYRDLD PRSPVGFELA SELKELETSD PKLFDIAKAI RDKVKAEKGL
PDNIDFFGGL IYHYMEIERL YYTPLFIMSR AAGWAAHAFE QRANNKIIRP NSEYTGPAPR
AFIPLSERE
//
