ID F4HR59_ARATH Unreviewed; 184 AA.
AC F4HR59;
DT 28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT 28-JUN-2011, sequence version 1.
DT 27-MAR-2024, entry version 79.
DE SubName: Full=Paired amphipathic helix repeat-containing protein {ECO:0000313|EMBL:AEE30796.1};
GN OrderedLocusNames=At1g27220 {ECO:0000313|EMBL:AEE30796.1};
GN ORFNames=F17L21.2 {ECO:0000313|EMBL:AEE30796.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702 {ECO:0000313|EMBL:AEE30796.1, ECO:0000313|Proteomes:UP000006548};
RN [1] {ECO:0000313|EMBL:AEE30796.1, ECO:0000313|Proteomes:UP000006548}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia {ECO:0000313|Proteomes:UP000006548};
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2] {ECO:0000313|Proteomes:UP000006548}
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia {ECO:0000313|Proteomes:UP000006548};
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00810}.
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DR EMBL; CP002684; AEE30796.1; -; Genomic_DNA.
DR RefSeq; NP_174042.1; NM_102484.1.
DR AlphaFoldDB; F4HR59; -.
DR SMR; F4HR59; -.
DR STRING; 3702.F4HR59; -.
DR PaxDb; 3702-AT1G27220-1; -.
DR ProteomicsDB; 197262; -.
DR EnsemblPlants; AT1G27220.1; AT1G27220.1; AT1G27220.
DR GeneID; 839611; -.
DR Gramene; AT1G27220.1; AT1G27220.1; AT1G27220.
DR KEGG; ath:AT1G27220; -.
DR TAIR; AT1G27220; -.
DR eggNOG; KOG1075; Eukaryota.
DR eggNOG; KOG4204; Eukaryota.
DR HOGENOM; CLU_1470150_0_0_1; -.
DR InParanoid; F4HR59; -.
DR OrthoDB; 1785701at2759; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; F4HR59; baseline and differential.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0004523; F:RNA-DNA hybrid ribonuclease activity; IEA:InterPro.
DR GO; GO:0003714; F:transcription corepressor activity; IEA:InterPro.
DR CDD; cd06222; RNase_H_like; 1.
DR Gene3D; 1.20.1160.11; Paired amphipathic helix; 1.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR InterPro; IPR003822; PAH.
DR InterPro; IPR036600; PAH_sf.
DR InterPro; IPR044730; RNase_H-like_dom_plant.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR002156; RNaseH_domain.
DR InterPro; IPR036397; RNaseH_sf.
DR InterPro; IPR039774; Sin3-like.
DR PANTHER; PTHR12346:SF0; SIN3A, ISOFORM G; 1.
DR PANTHER; PTHR12346; SIN3B-RELATED; 1.
DR Pfam; PF02671; PAH; 1.
DR Pfam; PF13456; RVT_3; 1.
DR SUPFAM; SSF47762; PAH2 domain; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR PROSITE; PS51477; PAH; 1.
PE 1: Evidence at protein level;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00810};
KW Proteomics identification {ECO:0007829|PeptideAtlas:F4HR59};
KW Reference proteome {ECO:0000313|Proteomes:UP000006548};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transcription {ECO:0000256|ARBA:ARBA00023163}.
FT DOMAIN 86..169
FT /note="RNase H type-1"
FT /evidence="ECO:0000259|Pfam:PF13456"
SQ SEQUENCE 184 AA; 21359 MW; 1232F3C1DFBB0C78 CRC64;
MAGEGSKPKA TVDDAYAYIR TVKSTFHNDP DKYDDFMAIM KNFKARKIDR NTCIEEVKEL
LKGHRDLISG FNAFLPKCLE IADWYNIEVL EAELQALLMA MQHTWSKGYR KIIFEGDNRT
VESLLNGNTR NFELHNLIIE IQHWRKKFSN AIIKWSFRST NKAADRLAKG ELENNVTFVS
HSTR
//
