ID F4HU00_ARATH Unreviewed; 825 AA.
AC F4HU00;
DT 28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 2.
DT 27-MAR-2024, entry version 94.
DE RecName: Full=Plasma membrane ATPase {ECO:0000256|RuleBase:RU362083};
DE EC=7.1.2.1 {ECO:0000256|RuleBase:RU362083};
GN Name=HA9 {ECO:0000313|EMBL:AEE36434.2, ECO:0000313|TAIR:AT1G80660};
GN Synonyms=AHA9 {ECO:0000313|EMBL:AEE36434.2}, H(+)-ATPase 9
GN {ECO:0000313|EMBL:AEE36434.2};
GN OrderedLocusNames=At1g80660 {ECO:0000313|Araport:AT1G80660,
GN ECO:0000313|EMBL:AEE36434.2};
GN ORFNames=F23A5.1 {ECO:0000313|EMBL:AEE36434.2}, F23A5_1
GN {ECO:0000313|EMBL:AEE36434.2};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702 {ECO:0000313|EMBL:AEE36434.2, ECO:0000313|Proteomes:UP000006548};
RN [1] {ECO:0000313|EMBL:AEE36434.2, ECO:0000313|Proteomes:UP000006548}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia {ECO:0000313|Proteomes:UP000006548};
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2] {ECO:0000313|Proteomes:UP000006548}
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia {ECO:0000313|Proteomes:UP000006548};
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H(+)(in) + H2O = ADP + 2 H(+)(out) + phosphate;
CC Xref=Rhea:RHEA:20852, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:30616, ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=7.1.2.1;
CC Evidence={ECO:0000256|ARBA:ARBA00001250,
CC ECO:0000256|RuleBase:RU362083};
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU362083};
CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU362083}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the cation transport ATPase (P-type) (TC 3.A.3)
CC family. Type IIIA subfamily. {ECO:0000256|ARBA:ARBA00008804,
CC ECO:0000256|RuleBase:RU362083}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|RuleBase:RU362083}.
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DR EMBL; CP002684; AEE36434.2; -; Genomic_DNA.
DR RefSeq; NP_001319430.1; NM_001334999.1.
DR AlphaFoldDB; F4HU00; -.
DR SMR; F4HU00; -.
DR EnsemblPlants; AT1G80660.2; AT1G80660.2; AT1G80660.
DR GeneID; 844405; -.
DR Gramene; AT1G80660.2; AT1G80660.2; AT1G80660.
DR Araport; AT1G80660; -.
DR TAIR; AT1G80660; HA9.
DR HOGENOM; CLU_002360_6_4_1; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; F4HU00; baseline and differential.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0008553; F:P-type proton-exporting transporter activity; IEA:UniProtKB-UniRule.
DR GO; GO:0120029; P:proton export across plasma membrane; IEA:UniProtKB-UniRule.
DR CDD; cd02076; P-type_ATPase_H; 1.
DR Gene3D; 6.10.140.890; -; 1.
DR Gene3D; 3.40.1110.10; Calcium-transporting ATPase, cytoplasmic domain N; 1.
DR Gene3D; 2.70.150.10; Calcium-transporting ATPase, cytoplasmic transduction domain A; 1.
DR Gene3D; 1.20.1110.10; Calcium-transporting ATPase, transmembrane domain; 1.
DR Gene3D; 3.40.50.1000; HAD superfamily/HAD-like; 1.
DR InterPro; IPR023299; ATPase_P-typ_cyto_dom_N.
DR InterPro; IPR018303; ATPase_P-typ_P_site.
DR InterPro; IPR023298; ATPase_P-typ_TM_dom_sf.
DR InterPro; IPR008250; ATPase_P-typ_transduc_dom_A_sf.
DR InterPro; IPR036412; HAD-like_sf.
DR InterPro; IPR023214; HAD_sf.
DR InterPro; IPR006534; P-type_ATPase_IIIA.
DR InterPro; IPR001757; P_typ_ATPase.
DR InterPro; IPR044492; P_typ_ATPase_HD_dom.
DR NCBIfam; TIGR01647; ATPase-IIIA_H; 1.
DR NCBIfam; TIGR01494; ATPase_P-type; 2.
DR PANTHER; PTHR42861:SF145; ATPASE 9, PLASMA MEMBRANE-TYPE; 1.
DR PANTHER; PTHR42861; CALCIUM-TRANSPORTING ATPASE; 1.
DR Pfam; PF00122; E1-E2_ATPase; 1.
DR Pfam; PF00702; Hydrolase; 1.
DR PRINTS; PR00119; CATATPASE.
DR PRINTS; PR00120; HATPASE.
DR SFLD; SFLDS00003; Haloacid_Dehalogenase; 1.
DR SFLD; SFLDF00027; p-type_atpase; 1.
DR SUPFAM; SSF81653; Calcium ATPase, transduction domain A; 1.
DR SUPFAM; SSF81665; Calcium ATPase, transmembrane domain M; 1.
DR SUPFAM; SSF56784; HAD-like; 1.
DR PROSITE; PS00154; ATPASE_E1_E2; 1.
PE 1: Evidence at protein level;
KW ATP-binding {ECO:0000256|RuleBase:RU362083};
KW Hydrogen ion transport {ECO:0000256|RuleBase:RU362083};
KW Ion transport {ECO:0000256|RuleBase:RU362083};
KW Magnesium {ECO:0000256|RuleBase:RU362083};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU362083};
KW Nucleotide-binding {ECO:0000256|RuleBase:RU362083};
KW Proteomics identification {ECO:0007829|PeptideAtlas:F4HU00,
KW ECO:0007829|ProteomicsDB:F4HU00};
KW Reference proteome {ECO:0000313|Proteomes:UP000006548};
KW Translocase {ECO:0000256|ARBA:ARBA00022967, ECO:0000256|RuleBase:RU362083};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU362083};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU362083}; Transport {ECO:0000256|RuleBase:RU362083}.
FT TRANSMEM 115..141
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362083"
FT TRANSMEM 153..175
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362083"
FT TRANSMEM 521..543
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362083"
FT TRANSMEM 586..607
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362083"
FT TRANSMEM 660..681
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362083"
FT TRANSMEM 693..717
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362083"
SQ SEQUENCE 825 AA; 90978 MW; 8FD50A77CED00880 CRC64;
MAGLAPKTKV LRDGKWSEQE AAILVPGDII SIKLGDIVPA DGRLLDGDPL KIDQSALTGE
SLPVTKHPGQ EVYSGSTCKQ GELEAVVIAT GVHTFFGKAA HLVDSTNQEG HFQKVLTAIG
NFCICSIAIG MLIEIVVMYP IQKRAYRDGI DNLLVLLIGG IPIAMPTVLS VTMAIGSHRL
SQQGAITKRM TAIEEMAGMD VLCSDKTGTL TLNKLTVDKS MVEVFVKDLD KDQLLVNAAR
ASRVENQDAI DACIVGMLGD PREAREGITE VHFFPFNPVD KRTAITYIDA NGNWHRVSKG
APEQIIELCN LREDASKRAH DIIDKFADRG LRSLAVGRQT VSEKDKNSPG EPWQFLGLLP
LFDPPRHDSA ETIRRALDLG VNVKMITGDQ LAIGKETGRR LGMGTNMYPS SALLGQDKDE
SIASLPVDEL IEKADGFAGV FPEHKYEIVK RLQEMKHICG MTGDGVNDAP ALKRADIGIA
VADATDAARS ASDIVLTEPG LSVIVSAVLT SRAIFQRMKN YTIYAVSITI RIVMGFMLLA
LIWKFDFSPF MVLIVAILND GTIMTISKDR VKPSPLPDSW KLKEIFATGV VLGTYLAVMT
VVFFWAAEST DFFSAKFGVR SISGNPHELT AAVYLQVSIV SQALIFVTRS RSWSYVERPG
FWLISAFFMA QLIATLIAVY ANWNFARIRG IGWGWAGVIW LYSIVFYIPL DILKFIIRYS
LSGRAWDNVI ENKTAFTSKK DYGKGEREAQ WAQAQRTLHG LQPAQTSDMF NDKSTYRELS
EIADQAKRRA EVARLRERHT LKGHVESVVK QKGLDIEAIQ QHYTL
//
