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Database: UniProt
Entry: F4I2H2
LinkDB: F4I2H2
Original site: F4I2H2 
ID   CHR9_ARATH              Reviewed;         862 AA.
AC   F4I2H2; Q9ZW97;
DT   29-OCT-2014, integrated into UniProtKB/Swiss-Prot.
DT   28-JUN-2011, sequence version 1.
DT   16-OCT-2019, entry version 58.
DE   RecName: Full=Switch 2 {ECO:0000312|EMBL:AEE27606.1};
DE            EC=3.6.4.-;
DE   AltName: Full=Protein CHROMATIN REMODELING 9 {ECO:0000303|PubMed:16547115};
DE            Short=AtCHR9;
GN   Name=SWI2 {ECO:0000312|EMBL:AEE27606.1};
GN   Synonyms=CHR9 {ECO:0000303|PubMed:16547115};
GN   OrderedLocusNames=At1g03750 {ECO:0000312|Araport:AT1G03750};
GN   ORFNames=F11M21.32 {ECO:0000312|EMBL:AAD10693.1};
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae;
OC   Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae;
OC   Arabidopsis.
OX   NCBI_TaxID=3702 {ECO:0000312|Proteomes:UP000006548};
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=11130712; DOI=10.1038/35048500;
RA   Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S.,
RA   White O., Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y.,
RA   Buehler E., Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W.,
RA   Chung M.K., Conn L., Conway A.B., Conway A.R., Creasy T.H., Dewar K.,
RA   Dunn P., Etgu P., Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y.,
RA   Gill J.E., Goldsmith A.D., Haas B., Hansen N.F., Hughes B., Huizar L.,
RA   Hunter J.L., Jenkins J., Johnson-Hopson C., Khan S., Khaykin E.,
RA   Kim C.J., Koo H.L., Kremenetskaia I., Kurtz D.B., Kwan A., Lam B.,
RA   Langin-Hooper S., Lee A., Lee J.M., Lenz C.A., Li J.H., Li Y.-P.,
RA   Lin X., Liu S.X., Liu Z.A., Luros J.S., Maiti R., Marziali A.,
RA   Militscher J., Miranda M., Nguyen M., Nierman W.C., Osborne B.I.,
RA   Pai G., Peterson J., Pham P.K., Rizzo M., Rooney T., Rowley D.,
RA   Sakano H., Salzberg S.L., Schwartz J.R., Shinn P., Southwick A.M.,
RA   Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA   Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M.,
RA   Wu D., Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT   "Sequence and analysis of chromosome 1 of the plant Arabidopsis
RT   thaliana.";
RL   Nature 408:816-820(2000).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana
RT   reference genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   GENE FAMILY, AND NOMENCLATURE.
RX   PubMed=16547115; DOI=10.1534/genetics.105.051664;
RA   Shaked H., Avivi-Ragolsky N., Levy A.A.;
RT   "Involvement of the Arabidopsis SWI2/SNF2 chromatin remodeling gene
RT   family in DNA damage response and recombination.";
RL   Genetics 173:985-994(2006).
RN   [4]
RP   GENE FAMILY.
RX   PubMed=24265739; DOI=10.1371/journal.pone.0078982;
RA   Xu R., Zhang S., Huang J., Zheng C.;
RT   "Genome-wide comparative in silico analysis of the RNA helicase gene
RT   family in Zea mays and Glycine max: a comparison with Arabidopsis and
RT   Oryza sativa.";
RL   PLoS ONE 8:E78982-E78982(2013).
CC   -!- FUNCTION: May be involved in early DNA damage response (By
CC       similarity). Probable chromatin remodeling factor.
CC       {ECO:0000250|UniProtKB:Q5T890, ECO:0000303|PubMed:16547115}.
CC   -!- SIMILARITY: Belongs to the SNF2/RAD54 helicase family.
CC       {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAD10693.1; Type=Erroneous gene model prediction;
DR   EMBL; AC003027; AAD10693.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; CP002684; AEE27606.1; -; Genomic_DNA.
DR   PIR; H86167; H86167.
DR   RefSeq; NP_171871.2; NM_100254.4.
DR   SMR; F4I2H2; -.
DR   BioGrid; 24652; 2.
DR   IntAct; F4I2H2; 2.
DR   STRING; 3702.AT1G03750.1; -.
DR   iPTMnet; F4I2H2; -.
DR   PaxDb; F4I2H2; -.
DR   EnsemblPlants; AT1G03750.1; AT1G03750.1; AT1G03750.
DR   GeneID; 839417; -.
DR   Gramene; AT1G03750.1; AT1G03750.1; AT1G03750.
DR   KEGG; ath:AT1G03750; -.
DR   Araport; AT1G03750; -.
DR   TAIR; locus:2024198; AT1G03750.
DR   eggNOG; KOG0387; Eukaryota.
DR   eggNOG; ENOG410XP4Z; LUCA.
DR   InParanoid; F4I2H2; -.
DR   KO; K20098; -.
DR   OMA; QTRYFEG; -.
DR   OrthoDB; 372069at2759; -.
DR   PRO; PR:F4I2H2; -.
DR   Proteomes; UP000006548; Chromosome 1.
DR   ExpressionAtlas; F4I2H2; baseline and differential.
DR   Genevisible; F4I2H2; AT.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.10810; -; 1.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR038718; SNF2-like_sf.
DR   InterPro; IPR000330; SNF2_N.
DR   Pfam; PF00271; Helicase_C; 1.
DR   Pfam; PF00176; SNF2_N; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SUPFAM; SSF52540; SSF52540; 2.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Coiled coil; Complete proteome; DNA damage; DNA repair;
KW   DNA-binding; Helicase; Hydrolase; Nucleotide-binding;
KW   Reference proteome.
FT   CHAIN         1    862       Switch 2.
FT                                /FTId=PRO_0000430855.
FT   DOMAIN      151    323       Helicase ATP-binding.
FT                                {ECO:0000255|PROSITE-ProRule:PRU00541}.
FT   DOMAIN      532    685       Helicase C-terminal.
FT                                {ECO:0000255|PROSITE-ProRule:PRU00542}.
FT   NP_BIND     164    171       ATP. {ECO:0000255|PROSITE-
FT                                ProRule:PRU00541}.
FT   COILED      274    294       {ECO:0000255}.
FT   MOTIF       274    277       DEAH box. {ECO:0000255|PROSITE-
FT                                ProRule:PRU00541}.
SQ   SEQUENCE   862 AA;  98486 MW;  9537F3E6E130CCE1 CRC64;
     MSLLHTFKET LKPCGSFPSS SSLRVSSTQE LEPSRKPPKS SLSQQLLRLD DSYFLPSKHE
     SKISKTQVED FDHNEDDHKR NIKFDEEEVD EDDERSIEFG RPGLSRAEFD YSGPYEPLML
     SSIGEIPIIH VPASINCRLL EHQREGVKFM YNLYKNNHGG ILGDDMGLGK TIQTIAFLAA
     VYGKDGDAGE SCLLESDKGP VLIICPSSII HNWESEFSRW ASFFKVSVYH GSNRDMILEK
     LKARGVEVLV TSFDTFRIQG PVLSGINWEI VIADEAHRLK NEKSKLYEAC LEIKTKKRIG
     LTGTVMQNKI SELFNLFEWV APGSLGTREH FRDFYDEPLK LGQRATAPER FVQIADKRKQ
     HLGSLLRKYM LRRTKEETIG HLMMGKEDNV VFCQMSQLQR RVYQRMIQLP EIQCLVNKDN
     PCACGSPLKQ SECCRRIVPD GTIWSYLHRD NHDGCDSCPF CLVLPCLMKL QQISNHLELI
     KPNPKDEPEK QKKDAEFVST VFGTDIDLLG GISASKSFMD LSDVKHCGKM RALEKLMASW
     ISKGDKILLF SYSVRMLDIL EKFLIRKGYS FARLDGSTPT NLRQSLVDDF NASPSKQVFL
     ISTKAGGLGL NLVSANRVVI FDPNWNPSHD LQAQDRSFRY GQKRHVVVFR LLSAGSLEEL
     VYTRQVYKQQ LSNIAVAGKM ETRYFEGVQD CKEFQGELFG ISNLFRDLSD KLFTSDIVEL
     HRDSNIDENK KRSLLETGVS EDEKEEEVMC SYKPEMEKPI LKDLGIVYAH RNEDIINIGE
     TTTSTSQRLN GDGNSADRKK KKRKGCSEEE DMSSSNREQK REKYKMLAEF KGMEILEFSR
     WVLSASPFDR EKLLQDFLER VK
//
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