ID F4ICK7_ARATH Unreviewed; 493 AA.
AC F4ICK7;
DT 28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT 28-JUN-2011, sequence version 1.
DT 13-SEP-2023, entry version 71.
DE SubName: Full=Transcription elongation factor (TFIIS) family protein {ECO:0000313|EMBL:AEE31439.1};
GN Name=IWS1 {ECO:0000313|EMBL:AEE31439.1, ECO:0000313|TAIR:AT1G32130};
GN Synonyms=ATIWS1 {ECO:0000313|EMBL:AEE31439.1}, HIGH NITROGEN
GN INSENSITIVE 9 {ECO:0000313|EMBL:AEE31439.1}, HNI9
GN {ECO:0000313|EMBL:AEE31439.1};
GN OrderedLocusNames=At1g32130 {ECO:0000313|Araport:AT1G32130,
GN ECO:0000313|EMBL:AEE31439.1};
GN ORFNames=F3C3.8 {ECO:0000313|EMBL:AEE31439.1}, F3C3_8
GN {ECO:0000313|EMBL:AEE31439.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702 {ECO:0000313|EMBL:AEE31439.1, ECO:0000313|Proteomes:UP000006548};
RN [1] {ECO:0000313|EMBL:AEE31439.1, ECO:0000313|Proteomes:UP000006548}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia {ECO:0000313|Proteomes:UP000006548};
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2] {ECO:0007829|PubMed:19245862}
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=19245862; DOI=10.1016/j.jprot.2009.02.004;
RA Jones A.M., MacLean D., Studholme D.J., Serna-Sanz A., Andreasson E.,
RA Rathjen J.P., Peck S.C.;
RT "Phosphoproteomic analysis of nuclei-enriched fractions from Arabidopsis
RT thaliana.";
RL J. Proteomics 72:439-451(2009).
RN [3] {ECO:0007829|PubMed:19376835}
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=19376835; DOI=10.1104/pp.109.138677;
RA Reiland S., Messerli G., Baerenfaller K., Gerrits B., Endler A.,
RA Grossmann J., Gruissem W., Baginsky S.;
RT "Large-scale Arabidopsis phosphoproteome profiling reveals novel
RT chloroplast kinase substrates and phosphorylation networks.";
RL Plant Physiol. 150:889-903(2009).
RN [4] {ECO:0000313|Proteomes:UP000006548}
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia {ECO:0000313|Proteomes:UP000006548};
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00649}.
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DR EMBL; CP002684; AEE31439.1; -; Genomic_DNA.
DR RefSeq; NP_001185126.1; NM_001198197.1.
DR AlphaFoldDB; F4ICK7; -.
DR SMR; F4ICK7; -.
DR ProteomicsDB; 204094; -.
DR EnsemblPlants; AT1G32130.2; AT1G32130.2; AT1G32130.
DR GeneID; 840105; -.
DR Gramene; AT1G32130.2; AT1G32130.2; AT1G32130.
DR Araport; AT1G32130; -.
DR TAIR; AT1G32130; IWS1.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; F4ICK7; baseline and differential.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
DR GO; GO:0009742; P:brassinosteroid mediated signaling pathway; IEA:InterPro.
DR GO; GO:0032784; P:regulation of DNA-templated transcription elongation; IEA:InterPro.
DR Gene3D; 1.20.930.10; Conserved domain common to transcription factors TFIIS, elongin A, CRSP70; 1.
DR InterPro; IPR044204; IWS1/2.
DR InterPro; IPR035441; TFIIS/LEDGF_dom_sf.
DR InterPro; IPR017923; TFIIS_N.
DR PANTHER; PTHR47350; PROTEIN IWS1 HOMOLOG 1; 1.
DR PANTHER; PTHR47350:SF4; PROTEIN IWS1 HOMOLOG 1; 1.
DR Pfam; PF08711; Med26; 1.
DR PROSITE; PS51319; TFIIS_N; 1.
PE 1: Evidence at protein level;
KW Elongation factor {ECO:0000313|EMBL:AEE31439.1};
KW Nucleus {ECO:0000256|PROSITE-ProRule:PRU00649};
KW Protein biosynthesis {ECO:0000313|EMBL:AEE31439.1};
KW Proteomics identification {ECO:0007829|PeptideAtlas:F4ICK7,
KW ECO:0007829|ProteomicsDB:F4ICK7};
KW Reference proteome {ECO:0000313|Proteomes:UP000006548}.
FT DOMAIN 287..370
FT /note="TFIIS N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51319"
FT REGION 1..61
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 87..208
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 385..435
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..33
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 108..163
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 170..200
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 398..416
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 417..431
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 493 AA; 56328 MW; 928A311987C6A744 CRC64;
MGFEDDPYRD VDGEPIVDFD DFGNDREPST EPLQDFDEDL ADDIGDWDGE GSQTPVYDND
KVAKPRKRLV KKSSSERVTI DVPELIDEDV DDAEFDEFMG GRGGGSTDYD DKVGRKRKKE
KERSSSGSGK EKRHKFPNRG ERKSEEIDEM WKSIAHNPEN DEEGVRTMDD DNFIDDTGLD
PSERYGGDAG DRSPTHYPQA EEGEDEDEVN NLFKMGKKKK KTERNPAEIA LLVENVMAEL
EVTAEEDAEL NRQGKPAINK LKKLSLLTDV LGKKQLQTEF LDHGVLTLLK NWLEPLPDGS
LPNINIRAAI LRVLTDFPID LDQYDRREQL KKSGLGKVIM FLSKSDEETN SNRRLAKDLV
DKWSRPIFNK STRFEDMRNL DEDRVPYRRP PVKKPSNKAT MESRDGDFDL EIRERKTGLT
SGQSSRGDRQ MTMRPEATPL DFLIRPQSKI DPDEIIARAK QMNKKLQQLK GTKKKRLQAT
KVSVEGRGMI KYL
//
