ID F4IF05_ARATH Unreviewed; 438 AA.
AC F4IF05;
DT 28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT 28-JUN-2011, sequence version 1.
DT 13-SEP-2023, entry version 71.
DE SubName: Full=Disease resistance protein (TIR-NBS class) {ECO:0000313|EMBL:AEE35387.1};
GN OrderedLocusNames=At1g72890 {ECO:0000313|Araport:AT1G72890,
GN ECO:0000313|EMBL:AEE35387.1};
GN ORFNames=F3N23.9 {ECO:0000313|EMBL:AEE35387.1}, F3N23_9
GN {ECO:0000313|EMBL:AEE35387.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702 {ECO:0000313|EMBL:AEE35387.1, ECO:0000313|Proteomes:UP000006548};
RN [1] {ECO:0000313|EMBL:AEE35387.1, ECO:0000313|Proteomes:UP000006548}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia {ECO:0000313|Proteomes:UP000006548};
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2] {ECO:0000313|Proteomes:UP000006548}
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia {ECO:0000313|Proteomes:UP000006548};
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP002684; AEE35387.1; -; Genomic_DNA.
DR RefSeq; NP_177432.1; NM_105947.2.
DR AlphaFoldDB; F4IF05; -.
DR SMR; F4IF05; -.
DR EnsemblPlants; AT1G72890.1; AT1G72890.1; AT1G72890.
DR GeneID; 843620; -.
DR Gramene; AT1G72890.1; AT1G72890.1; AT1G72890.
DR Araport; AT1G72890; -.
DR TAIR; AT1G72890; -.
DR HOGENOM; CLU_001561_2_3_1; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; F4IF05; baseline and differential.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0006952; P:defense response; IEA:InterPro.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.40.50.10140; Toll/interleukin-1 receptor homology (TIR) domain; 1.
DR InterPro; IPR044974; Disease_R_plants.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000157; TIR_dom.
DR InterPro; IPR035897; Toll_tir_struct_dom_sf.
DR PANTHER; PTHR11017:SF389; DISEASE RESISTANCE PROTEIN (TIR-NBS CLASS); 1.
DR PANTHER; PTHR11017; LEUCINE-RICH REPEAT-CONTAINING PROTEIN; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR Pfam; PF01582; TIR; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SMART; SM00255; TIR; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF52200; Toll/Interleukin receptor TIR domain; 1.
DR PROSITE; PS50104; TIR; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000006548}.
FT DOMAIN 37..202
FT /note="TIR"
FT /evidence="ECO:0000259|PROSITE:PS50104"
SQ SEQUENCE 438 AA; 50622 MW; C90A2386F947BB9D CRC64;
MNTIFKKLSC FKKKVKSLRI FESRSLSSSS SSSFTPQKFD VFLSFRGKDT RKNFVSFLYK
ALVSKGIRTF KDDEELERGR PIPPELRQAI KGSRIAVVVV SVTYPASSWC LEELREILKL
EKLGLLTVIP IFYEINPSDV RRQSGVVSKQ FKKHEKRQSR ERVKSWREAL TKLASLSGEC
SKNWEDDSKL VDGITEKIST KLFSEKPRND NILIGIDQHM GELYPLFNLN SNEDVQVIGI
WGRGSNGRSA LASHVYQNIK HHFEAHCFLE DVRRISLHFR DSHLQDELLS NMQGEGLTTK
NCHRCLKTIK ARLRNKKVLL VANDVDKLEQ FDALAEEFSW FGPGSRIIIT TQDRQLLISS
VVRSVYEVKL LRCYAVRELF RSNAFKERER DDPVGFDQST YRAMYISGHV FLTLRYIFTL
LCDRGQLRER INAIVHSL
//
