GenomeNet

Database: UniProt
Entry: F4INA9
LinkDB: F4INA9
Original site: F4INA9 
ID   RECG_ARATH              Reviewed;         973 AA.
AC   F4INA9; Q9ZVG0;
DT   20-JAN-2016, integrated into UniProtKB/Swiss-Prot.
DT   28-JUN-2011, sequence version 1.
DT   31-JUL-2019, entry version 65.
DE   RecName: Full=ATP-dependent DNA helicase homolog RECG, chloroplastic {ECO:0000305};
DE            EC=3.6.4.12 {ECO:0000305};
DE   Flags: Precursor;
GN   Name=RECG {ECO:0000305};
GN   OrderedLocusNames=At2g01440 {ECO:0000312|Araport:AT2G01440};
GN   ORFNames=F2I9.6 {ECO:0000312|EMBL:AAC67321.1};
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae;
OC   Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae;
OC   Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=10617197; DOI=10.1038/45471;
RA   Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA   Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA   Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L.,
RA   Moffat K.S., Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L.,
RA   Tallon L.J., Gill J.E., Adams M.D., Carrera A.J., Creasy T.H.,
RA   Goodman H.M., Somerville C.R., Copenhaver G.P., Preuss D.,
RA   Nierman W.C., White O., Eisen J.A., Salzberg S.L., Fraser C.M.,
RA   Venter J.C.;
RT   "Sequence and analysis of chromosome 2 of the plant Arabidopsis
RT   thaliana.";
RL   Nature 402:761-768(1999).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana
RT   reference genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   GENE FAMILY.
RX   PubMed=24265739; DOI=10.1371/journal.pone.0078982;
RA   Xu R., Zhang S., Huang J., Zheng C.;
RT   "Genome-wide comparative in silico analysis of the RNA helicase gene
RT   family in Zea mays and Glycine max: a comparison with Arabidopsis and
RT   Oryza sativa.";
RL   PLoS ONE 8:E78982-E78982(2013).
CC   -!- FUNCTION: Critical role in recombination and DNA repair.
CC       {ECO:0000250|UniProtKB:P24230}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC         Evidence={ECO:0000305};
CC   -!- SUBCELLULAR LOCATION: Plastid, chloroplast {ECO:0000255}.
CC   -!- SIMILARITY: Belongs to the helicase family. RecG subfamily.
CC       {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAC67321.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
DR   EMBL; AC005560; AAC67321.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; CP002685; AEC05451.1; -; Genomic_DNA.
DR   PIR; G84424; G84424.
DR   RefSeq; NP_178253.3; NM_126205.4.
DR   SMR; F4INA9; -.
DR   STRING; 3702.AT2G01440.1; -.
DR   iPTMnet; F4INA9; -.
DR   PaxDb; F4INA9; -.
DR   EnsemblPlants; AT2G01440.1; AT2G01440.1; AT2G01440.
DR   GeneID; 814672; -.
DR   Gramene; AT2G01440.1; AT2G01440.1; AT2G01440.
DR   KEGG; ath:AT2G01440; -.
DR   Araport; AT2G01440; -.
DR   TAIR; locus:2049541; AT2G01440.
DR   eggNOG; KOG0344; Eukaryota.
DR   eggNOG; ENOG410XQS8; LUCA.
DR   InParanoid; F4INA9; -.
DR   KO; K03655; -.
DR   OMA; HYDLREY; -.
DR   OrthoDB; 142915at2759; -.
DR   PRO; PR:F4INA9; -.
DR   Proteomes; UP000006548; Chromosome 2.
DR   ExpressionAtlas; F4INA9; baseline and differential.
DR   GO; GO:0009507; C:chloroplast; IDA:TAIR.
DR   GO; GO:0005739; C:mitochondrion; IDA:TAIR.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003678; F:DNA helicase activity; IBA:GO_Central.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR   GO; GO:0006281; P:DNA repair; IMP:TAIR.
DR   GO; GO:0033955; P:mitochondrial DNA inheritance; IMP:TAIR.
DR   InterPro; IPR004609; ATP-dep_DNA_helicase_RecG.
DR   InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR012340; NA-bd_OB-fold.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF00270; DEAD; 1.
DR   Pfam; PF00271; Helicase_C; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SUPFAM; SSF50249; SSF50249; 2.
DR   SUPFAM; SSF52540; SSF52540; 2.
DR   TIGRFAMs; TIGR00643; recG; 1.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Chloroplast; Complete proteome; DNA damage;
KW   DNA recombination; DNA repair; DNA-binding; Helicase; Hydrolase;
KW   Nucleotide-binding; Plastid; Reference proteome; Transit peptide.
FT   TRANSIT       1     24       Chloroplast. {ECO:0000255}.
FT   CHAIN        25    973       ATP-dependent DNA helicase homolog RECG,
FT                                chloroplastic.
FT                                /FTId=PRO_0000435302.
FT   DOMAIN      536    725       Helicase ATP-binding.
FT                                {ECO:0000255|PROSITE-ProRule:PRU00541}.
FT   DOMAIN      746    904       Helicase C-terminal.
FT                                {ECO:0000255|PROSITE-ProRule:PRU00542}.
FT   NP_BIND     549    556       ATP. {ECO:0000255|PROSITE-
FT                                ProRule:PRU00541}.
FT   MOTIF       655    658       DEQQ box. {ECO:0000305}.
SQ   SEQUENCE   973 AA;  108376 MW;  1103AB392F115027 CRC64;
     MAAVTLSPCS MCCGSRRLRS VIVIQAQRGN WNRIRLSNFF FSKVWNISYR SKHKYSDNLL
     EQVEKYASAR LENQSKLITK VAALMECDNV DDFIDKKSDE QVKKDLVLAC KRFPSIILGD
     SRPVELYSNS KSYGESSSIL KTPTDNSFLP TPMHGGWFDP DNLSRTLSSF CPELLQNDDS
     SDPREDILDD GSSFTSKTAT SEVEATSDDV FAAQRFLATS IDSMPGLSKR HSNQLDSCGF
     HTMKKLLHHF PRTYADLQNA QVDIEDGQYL IFVGKVLSSK GVRASSSFSF LEVIVSCEVS
     GRDRTPEDLS HNAEDKAGKS IFLHLKKFFR GTRFTWQPFL NSIQEKHKVG DLVCISGKVK
     SLRAEDHFEM REYNIDVLKD EEESSHRAQG RPYPIYPSKG GLNPKFLSDV ISRALRVLPA
     NMDPIPKEIT KVFGLPSLND AYVGIHEPKT LDEADLARKR LIFDEFFYLQ LARLYQMLQS
     LGTKIEKDVL LEKFRKPVLN SVYIEEWSTL TKSFLKALPY SLTPSQLSAV SEIIWDLKRP
     VPMNRLLQGD VGCGKTVVAF LACMEVIGSG YQAAFMAPTE LLAIQHYEQC RDLLENMEGV
     SSKPTIGLLT GSTPAKQSRM IRQDLQSGAI SFIIGTHSLI AEKIEYSALR IAVVDEQQRF
     GVIQRGKFNS KLYGTSMISK SGSSDSDDTS KADLSMAPHV LAMSATPIPR SLALALYGDI
     SLTQITGMPL GRIPVETHIF EGNETGIKEV YSMMLEDLKS GGRVYVVYPV IDQSEQLPQL
     RAASAELEIV TKKFPKYNCG LLHGRMKSDD KEEALNKFRS GETQILLSTQ VIEIGVDVPD
     ASMMVVMNAE RFGIAQLHQL RGRVGRGTRK SKCLLVGSST NSLKRLNMLG KSSDGFYLAN
     IDLLLRGPGD LLGKKQSGHL PEFPVARLEI DGNMLQEAHI AALNVLGDSH DLEKFPALKA
     ELSMRQPLCL LGD
//
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