ID F4IPA6_ARATH Unreviewed; 744 AA.
AC F4IPA6;
DT 28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT 28-JUN-2011, sequence version 1.
DT 27-MAR-2024, entry version 80.
DE SubName: Full=ARM repeat superfamily protein {ECO:0000313|EMBL:AEC05486.1};
GN Name=VAC1 {ECO:0000313|TAIR:AT2G01690};
GN OrderedLocusNames=At2g01690 {ECO:0000313|Araport:AT2G01690,
GN ECO:0000313|EMBL:AEC05486.1};
GN ORFNames=T8O11.14 {ECO:0000313|EMBL:AEC05486.1}, T8O11_14
GN {ECO:0000313|EMBL:AEC05486.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702 {ECO:0000313|EMBL:AEC05486.1, ECO:0000313|Proteomes:UP000006548};
RN [1] {ECO:0000313|EMBL:AEC05486.1, ECO:0000313|Proteomes:UP000006548}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia {ECO:0000313|Proteomes:UP000006548};
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S., Shea T.P., Benito M.I., Town C.D.,
RA Fujii C.Y., Mason T., Bowman C.L., Barnstead M., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2] {ECO:0007829|PubMed:19245862}
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=19245862; DOI=10.1016/j.jprot.2009.02.004;
RA Jones A.M., MacLean D., Studholme D.J., Serna-Sanz A., Andreasson E.,
RA Rathjen J.P., Peck S.C.;
RT "Phosphoproteomic analysis of nuclei-enriched fractions from Arabidopsis
RT thaliana.";
RL J. Proteomics 72:439-451(2009).
RN [3] {ECO:0000313|Proteomes:UP000006548}
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia {ECO:0000313|Proteomes:UP000006548};
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
CC -!- SIMILARITY: Belongs to the VAC14 family.
CC {ECO:0000256|ARBA:ARBA00010225}.
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DR EMBL; CP002685; AEC05486.1; -; Genomic_DNA.
DR RefSeq; NP_973395.1; NM_201666.1.
DR AlphaFoldDB; F4IPA6; -.
DR SMR; F4IPA6; -.
DR ProteomicsDB; 201338; -.
DR EnsemblPlants; AT2G01690.2; AT2G01690.2; AT2G01690.
DR GeneID; 814698; -.
DR Gramene; AT2G01690.2; AT2G01690.2; AT2G01690.
DR Araport; AT2G01690; -.
DR TAIR; AT2G01690; VAC1.
DR HOGENOM; CLU_007740_0_0_1; -.
DR OMA; CYQHVSE; -.
DR OrthoDB; 5481081at2759; -.
DR PhylomeDB; F4IPA6; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; F4IPA6; baseline and differential.
DR GO; GO:0005739; C:mitochondrion; HDA:TAIR.
DR GO; GO:0070772; C:PAS complex; IEA:InterPro.
DR GO; GO:0000325; C:plant-type vacuole; HDA:TAIR.
DR GO; GO:0006661; P:phosphatidylinositol biosynthetic process; IEA:InterPro.
DR GO; GO:0009555; P:pollen development; IMP:TAIR.
DR GO; GO:0007033; P:vacuole organization; IMP:TAIR.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 3.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR021133; HEAT_type_2.
DR InterPro; IPR026825; Vac14.
DR InterPro; IPR021841; VAC14_Fig4p-bd.
DR PANTHER; PTHR16023:SF0; PROTEIN VAC14 HOMOLOG; 1.
DR PANTHER; PTHR16023; TAX1 BINDING PROTEIN-RELATED; 1.
DR Pfam; PF12755; Vac14_Fab1_bd; 1.
DR Pfam; PF11916; Vac14_Fig4_bd; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR PROSITE; PS50077; HEAT_REPEAT; 1.
PE 1: Evidence at protein level;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Proteomics identification {ECO:0007829|PeptideAtlas:F4IPA6,
KW ECO:0007829|ProteomicsDB:F4IPA6};
KW Reference proteome {ECO:0000313|Proteomes:UP000006548};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT REPEAT 92..127
FT /note="HEAT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
FT DOMAIN 430..609
FT /note="Vacuolar protein 14 C-terminal Fig4-binding"
FT /evidence="ECO:0000259|Pfam:PF11916"
FT REGION 625..648
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 671..744
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 671..688
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 698..744
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 744 AA; 84040 MW; B51BEA114882899B CRC64;
MSDALSAIPA AVHRNLSDKL YEKRKNAALE LENIVKNLTS SGDHDKISKV IEMLIKEFAK
SPQANHRKGG LIGLAAVTVG LSTEAAQYLE QIVPPVINSF SDQDSRVRYY ACEALYNIAK
VVRGDFIIFF NKIFDALCKL SADSDANVQS AAHLLDRLVK QDIVTESDQF SIEEFIPLLK
ERMNVLNPYV RQFLVGWITV LDSVPDIDML GFLPDFLDGL FNMLSDSSHE IRQQADSALS
EFLQEIKNSP SVDYGRMAEI LVQRAASPDE FTRLTAITWI NEFVKLGGDQ LVRYYADILG
AILPCISDKE EKIRVVARET NEELRSIHVE PSDGFDVGAI LSVARRQLSS EFEATRIEAL
NWISTLLNKH RTEVLCFLND IFDTLLKALS DSSDDVVLLV LEVHAGVAKD PQHFRQLIVF
LVHNFRADNS LLERRGALIV RRMCVLLDAE RVYRELSTIL EGEDNLDFAS TMVQALNLIL
LTSPELSKLR ELLKGSLVNR EGKELFVALY TSWCHSPMAI ISLCLLAQAY QHASVVIQSL
VEEDINVKFL VQLDKLIRLL ETPIFTYLRL QLLEPGRYTW LLKTLYGLLM LLPQQSAAFK
ILRTRLKTVP TYSFSTGNQI GRATSGVPFS QYKHQNEDGD LEDDNINSSH QGINFAVRLQ
QFENVQNLHR GQARTRVNYS YHSSSSSTSK EVRRSEEQQQ QQQQQQQQQQ QQQRPPPSST
SSSVADNNRP PSRTSRKGPG QLQL
//
