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Database: UniProt
Entry: F4IV99
LinkDB: F4IV99
Original site: F4IV99 
ID   CHR5_ARATH              Reviewed;        1724 AA.
AC   F4IV99; Q9SI41;
DT   29-OCT-2014, integrated into UniProtKB/Swiss-Prot.
DT   28-JUN-2011, sequence version 1.
DT   16-OCT-2019, entry version 59.
DE   RecName: Full=Protein CHROMATIN REMODELING 5 {ECO:0000303|PubMed:16547115};
DE            Short=AtCHR5;
DE            EC=3.6.4.-;
GN   Name=CHR5 {ECO:0000303|PubMed:16547115};
GN   OrderedLocusNames=At2g13370 {ECO:0000312|Araport:AT2G13370};
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae;
OC   Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae;
OC   Arabidopsis.
OX   NCBI_TaxID=3702 {ECO:0000312|Proteomes:UP000006548};
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=10617197; DOI=10.1038/45471;
RA   Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA   Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA   Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L.,
RA   Moffat K.S., Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L.,
RA   Tallon L.J., Gill J.E., Adams M.D., Carrera A.J., Creasy T.H.,
RA   Goodman H.M., Somerville C.R., Copenhaver G.P., Preuss D.,
RA   Nierman W.C., White O., Eisen J.A., Salzberg S.L., Fraser C.M.,
RA   Venter J.C.;
RT   "Sequence and analysis of chromosome 2 of the plant Arabidopsis
RT   thaliana.";
RL   Nature 402:761-768(1999).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana
RT   reference genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   GENE FAMILY, AND NOMENCLATURE.
RX   PubMed=16547115; DOI=10.1534/genetics.105.051664;
RA   Shaked H., Avivi-Ragolsky N., Levy A.A.;
RT   "Involvement of the Arabidopsis SWI2/SNF2 chromatin remodeling gene
RT   family in DNA damage response and recombination.";
RL   Genetics 173:985-994(2006).
RN   [4]
RP   GENE FAMILY.
RX   PubMed=24265739; DOI=10.1371/journal.pone.0078982;
RA   Xu R., Zhang S., Huang J., Zheng C.;
RT   "Genome-wide comparative in silico analysis of the RNA helicase gene
RT   family in Zea mays and Glycine max: a comparison with Arabidopsis and
RT   Oryza sativa.";
RL   PLoS ONE 8:E78982-E78982(2013).
CC   -!- FUNCTION: DNA-binding helicase that specifically binds to the
CC       promoter of target genes, leading to chromatin remodeling,
CC       possibly by promoting deposition of histone H3.3 (By similarity).
CC       Probable chromatin remodeling factor.
CC       {ECO:0000250|UniProtKB:E9PZM4, ECO:0000303|PubMed:16547115}.
CC   -!- INTERACTION:
CC       Q9LJG8:ASIL2; NbExp=4; IntAct=EBI-15203078, EBI-4427947;
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-
CC       ProRule:PRU00768}.
CC   -!- SIMILARITY: Belongs to the SNF2/RAD54 helicase family.
CC       {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAD28668.1; Type=Erroneous gene model prediction;
DR   EMBL; AC007209; AAD28668.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; CP002685; AEC06230.1; -; Genomic_DNA.
DR   EMBL; CP002685; ANM62965.1; -; Genomic_DNA.
DR   EMBL; CP002685; ANM62966.1; -; Genomic_DNA.
DR   PIR; C84507; C84507.
DR   RefSeq; NP_001325086.1; NM_001335390.1.
DR   RefSeq; NP_001325087.1; NM_001335389.1.
DR   RefSeq; NP_178970.3; NM_126926.5.
DR   SMR; F4IV99; -.
DR   BioGrid; 1184; 5.
DR   IntAct; F4IV99; 3.
DR   STRING; 3702.AT2G13370.1; -.
DR   iPTMnet; F4IV99; -.
DR   PaxDb; F4IV99; -.
DR   PRIDE; F4IV99; -.
DR   EnsemblPlants; AT2G13370.1; AT2G13370.1; AT2G13370.
DR   EnsemblPlants; AT2G13370.2; AT2G13370.2; AT2G13370.
DR   EnsemblPlants; AT2G13370.3; AT2G13370.3; AT2G13370.
DR   GeneID; 815823; -.
DR   Gramene; AT2G13370.1; AT2G13370.1; AT2G13370.
DR   Gramene; AT2G13370.2; AT2G13370.2; AT2G13370.
DR   Gramene; AT2G13370.3; AT2G13370.3; AT2G13370.
DR   KEGG; ath:AT2G13370; -.
DR   Araport; AT2G13370; -.
DR   TAIR; locus:2041644; AT2G13370.
DR   eggNOG; KOG0384; Eukaryota.
DR   eggNOG; COG0553; LUCA.
DR   InParanoid; F4IV99; -.
DR   KO; K11367; -.
DR   OMA; PAWQETF; -.
DR   OrthoDB; 57339at2759; -.
DR   PRO; PR:F4IV99; -.
DR   Proteomes; UP000006548; Chromosome 2.
DR   ExpressionAtlas; F4IV99; baseline and differential.
DR   Genevisible; F4IV99; AT.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0009506; C:plasmodesma; IDA:TAIR.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006325; P:chromatin organization; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.10810; -; 1.
DR   InterPro; IPR016197; Chromo-like_dom_sf.
DR   InterPro; IPR000953; Chromo/chromo_shadow_dom.
DR   InterPro; IPR023780; Chromo_domain.
DR   InterPro; IPR025260; DUF4208.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR038718; SNF2-like_sf.
DR   InterPro; IPR000330; SNF2_N.
DR   Pfam; PF00385; Chromo; 1.
DR   Pfam; PF13907; DUF4208; 1.
DR   Pfam; PF00271; Helicase_C; 1.
DR   Pfam; PF00176; SNF2_N; 1.
DR   SMART; SM00298; CHROMO; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM01176; DUF4208; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SUPFAM; SSF52540; SSF52540; 2.
DR   SUPFAM; SSF54160; SSF54160; 2.
DR   PROSITE; PS50013; CHROMO_2; 2.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
PE   1: Evidence at protein level;
KW   ATP-binding; Chromatin regulator; Coiled coil; Complete proteome;
KW   DNA-binding; Helicase; Hydrolase; Nucleotide-binding; Nucleus;
KW   Reference proteome; Repeat.
FT   CHAIN         1   1724       Protein CHROMATIN REMODELING 5.
FT                                /FTId=PRO_0000430853.
FT   DOMAIN      420    499       Chromo 1. {ECO:0000255|PROSITE-
FT                                ProRule:PRU00053}.
FT   DOMAIN      533    597       Chromo 2. {ECO:0000255|PROSITE-
FT                                ProRule:PRU00053}.
FT   DOMAIN      637    809       Helicase ATP-binding.
FT                                {ECO:0000255|PROSITE-ProRule:PRU00541}.
FT   DOMAIN      943   1094       Helicase C-terminal.
FT                                {ECO:0000255|PROSITE-ProRule:PRU00542}.
FT   NP_BIND     650    657       ATP. {ECO:0000255|PROSITE-
FT                                ProRule:PRU00541}.
FT   COILED      138    164       {ECO:0000255}.
FT   COILED      505    525       {ECO:0000255}.
FT   COILED     1126   1163       {ECO:0000255}.
FT   MOTIF       320    327       Nuclear localization signal 1.
FT                                {ECO:0000255|PROSITE-ProRule:PRU00768}.
FT   MOTIF       760    763       DEAH box. {ECO:0000255|PROSITE-
FT                                ProRule:PRU00541}.
FT   MOTIF      1224   1231       Nuclear localization signal 2.
FT                                {ECO:0000255|PROSITE-ProRule:PRU00768}.
FT   MOTIF      1348   1355       Nuclear localization signal 3.
FT                                {ECO:0000255|PROSITE-ProRule:PRU00768}.
FT   COMPBIAS    230    297       Asp-rich. {ECO:0000255|PROSITE-
FT                                ProRule:PRU00004}.
SQ   SEQUENCE   1724 AA;  197270 MW;  EABFB4A4DFB91476 CRC64;
     MAFFRNYSND TVSHNVLDEN EERQNAATFQ SSPLNEDVDG TYSERGFDMN MDVQYQSDPE
     PGCSIRQPNE TAVDNVADPV DSHYQSSTKR LGVTGRWGST FWKDCQPMGQ REGSDPAKDS
     QSGYKEAYHS EDNHSNDRSE KLDSENENDN ENEEEDNEMN KHQSGQADVP ADEMLSDEYY
     EQDEDNQSDH VHYKGYSNPT NSRSLPKAGS AVHSNSRTSR AIHKNIHYSD SNHDHNGDAD
     MDYEEEEDED DPEDADFEPY DAADDGGASK KHGQGWDVSD EDPESDEEID LSDYEDDYGT
     KKPKVRQQSK GFRKSSAGLE RKSFHVSSRQ KRKTSYQDDD SEEDSENDND EGFRSLARRG
     TTLRQNNGRS TNTIGQSSEV RSSTRSVRKV SYVESEDSED IDDGKNRKNQ KDDIEEEDAD
     VIEKVLWHQL KGMGEDVQTN NKSTVPVLVS QLFDTEPDWN EMEFLIKWKG QSHLHCQWKT
     LSDLQNLSGF KKVLNYTKKV TEEIRYRTAL SREEIEVNDV SKEMDLDIIK QNSQVERIIA
     DRISKDGLGD VVPEYLVKWQ GLSYAEATWE KDVDIAFAQV AIDEYKAREV SIAVQGKMVE
     QQRTKGKASL RKLDEQPEWL IGGTLRDYQL EGLNFLVNSW LNDTNVILAD EMGLGKTVQS
     VSMLGFLQNT QQIPGPFLVV VPLSTLANWA KEFRKWLPGM NIIVYVGTRA SREVCQQYEF
     YNEKKVGRPI KFNALLTTYE VVLKDKAVLS KIKWIYLMVD EAHRLKNSEA QLYTALLEFS
     TKNKLLITGT PLQNSVEELW ALLHFLDPGK FKNKDEFVEN YKNLSSFNES ELANLHLELR
     PHILRRVIKD VEKSLPPKIE RILRVEMSPL QKQYYKWILE RNFHDLNKGV RGNQVSLLNI
     VVELKKCCNH PFLFESADHG YGGDINDNSK LDKIILSSGK LVILDKLLVR LRETKHRVLI
     FSQMVRMLDI LAEYLSLRGF QFQRLDGSTK AELRQQAMDH FNAPASDDFC FLLSTRAGGL
     GINLATADTV VIFDSDWNPQ NDLQAMSRAH RIGQQEVVNI YRFVTSKSVE EEILERAKRK
     MVLDHLVIQK LNAEGRLEKR ETKKGSNFDK NELSAILRFG AEELFKEDKN DEESKKRLLS
     MDIDEILERA EQVEEKHTDE TEHELLGAFK VANFCNAEDD GSFWSRWIKP DSVVTAEEAL
     APRAARNTKS YVDPSHPDRT SKRKKKGSEP PEHTERSQKR RKTEYFVPST PLLEGTSAQV
     RGWSYGNLPK RDAQRFYRTV MKFGNHNQMA CIAEEVGGVV EAAPEEAQVE LFDALIDGCK
     ESVETGNFEP KGPVLDFFGV PVKANELLKR VQGLQLLSKR ISRYNDPISQ FRVLSYLKPS
     NWSKGCGWNQ IDDARLLLGI LYHGFGNWEK IRLDESLGLT KKIAPVELQH HETFLPRAPN
     LKERATALLE MELAAAGGKN TNAKASRKNS KKVKDNLINQ FKAPARDRRG KSGPANVSLL
     STKDGPRKTQ KAEPLVKEEG EMSDDGEVYE QFKEQKWMEW CEDVLADEIK TLGRLQRLQT
     TSADLPKEKV LFKIRRYLEI LGRRIDAIVL EHEEDLYKQD RMTMRLWNYV STFSNLSGDR
     LNQIYSKLKQ EKEEEEGVGP SHLNGSRNFQ RQQKFKTAGN SQGSQQVHKG IDTAKFEAWK
     RRRRTENDVQ TERPTITNSN SLGILGPGPL DRSHRARQTG FPPR
//
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