ID F4K7C5_ARATH Unreviewed; 1565 AA.
AC F4K7C5;
DT 28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT 28-JUN-2011, sequence version 1.
DT 27-MAR-2024, entry version 82.
DE SubName: Full=Myosin 2 {ECO:0000313|EMBL:AED95023.1};
GN Name=MYA2 {ECO:0000313|EMBL:AED95023.1, ECO:0000313|TAIR:AT5G43900};
GN Synonyms=ARABIDOPSIS MYOSIN 2 {ECO:0000313|EMBL:AED95023.1}, ATMYA2
GN {ECO:0000313|EMBL:AED95023.1}, myosin 2 {ECO:0000313|EMBL:AED95023.1},
GN MYOSIN X1 2 {ECO:0000313|EMBL:AED95023.1}, MYOSIN XI-6
GN {ECO:0000313|EMBL:AED95023.1}, XI-2 {ECO:0000313|EMBL:AED95023.1},
GN XI-6 {ECO:0000313|EMBL:AED95023.1};
GN OrderedLocusNames=At5g43900 {ECO:0000313|Araport:AT5G43900,
GN ECO:0000313|EMBL:AED95023.1};
GN ORFNames=F6B6.4 {ECO:0000313|EMBL:AED95023.1}, F6B6_4
GN {ECO:0000313|EMBL:AED95023.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702 {ECO:0000313|EMBL:AED95023.1, ECO:0000313|Proteomes:UP000006548};
RN [1] {ECO:0000313|EMBL:AED95023.1, ECO:0000313|Proteomes:UP000006548}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia {ECO:0000313|Proteomes:UP000006548};
RX PubMed=11130714; DOI=10.1038/35048507;
RG Kazusa DNA Research Institute;
RG Cold Spring Harbor and Washington University in St Louis Sequencing Consortium;
RG European Union Arabidopsis Genome Sequencing Consortium;
RA Tabata S., Kaneko T., Nakamura Y., Kotani H., Kato T., Asamizu E.,
RA Miyajima N., Sasamoto S., Kimura T., Hosouchi T., Kawashima K., Kohara M.,
RA Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Naruo K.,
RA Okumura S., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M.,
RA Yasuda M., Sato S., de la Bastide M., Huang E., Spiegel L., Gnoj L.,
RA O'Shaughnessy A., Preston R., Habermann K., Murray J., Johnson D.,
RA Rohlfing T., Nelson J., Stoneking T., Pepin K., Spieth J., Sekhon M.,
RA Armstrong J., Becker M., Belter E., Cordum H., Cordes M., Courtney L.,
RA Courtney W., Dante M., Du H., Edwards J., Fryman J., Haakensen B.,
RA Lamar E., Latreille P., Leonard S., Meyer R., Mulvaney E., Ozersky P.,
RA Riley A., Strowmatt C., Wagner-McPherson C., Wollam A., Yoakum M., Bell M.,
RA Dedhia N., Parnell L., Shah R., Rodriguez M., See L.H., Vil D., Baker J.,
RA Kirchoff K., Toth K., King L., Bahret A., Miller B., Marra M.,
RA Martienssen R., McCombie W.R., Wilson R.K., Murphy G., Bancroft I.,
RA Volckaert G., Wambutt R., Dusterhoft A., Stiekema W., Pohl T., Entian K.D.,
RA Terryn N., Hartley N., Bent E., Johnson S., Langham S.A., McCullagh B.,
RA Robben J., Grymonprez B., Zimmermann W., Ramsperger U., Wedler H.,
RA Balke K., Wedler E., Peters S., van Staveren M., Dirkse W., Mooijman P.,
RA Lankhorst R.K., Weitzenegger T., Bothe G., Rose M., Hauf J., Berneiser S.,
RA Hempel S., Feldpausch M., Lamberth S., Villarroel R., Gielen J.,
RA Ardiles W., Bents O., Lemcke K., Kolesov G., Mayer K., Rudd S., Schoof H.,
RA Schueller C., Zaccaria P., Mewes H.W., Bevan M., Fransz P.;
RT "Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana.";
RL Nature 408:823-826(2000).
RN [2] {ECO:0000313|Proteomes:UP000006548}
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia {ECO:0000313|Proteomes:UP000006548};
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Myosin family. Plant myosin class XI subfamily.
CC {ECO:0000256|ARBA:ARBA00008049}.
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DR EMBL; CP002688; AED95023.1; -; Genomic_DNA.
DR RefSeq; NP_001190465.1; NM_001203536.1.
DR SMR; F4K7C5; -.
DR EnsemblPlants; AT5G43900.3; AT5G43900.3; AT5G43900.
DR GeneID; 834412; -.
DR Gramene; AT5G43900.3; AT5G43900.3; AT5G43900.
DR Araport; AT5G43900; -.
DR TAIR; AT5G43900; MYA2.
DR OrthoDB; 5489458at2759; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; F4K7C5; baseline and differential.
DR GO; GO:0005829; C:cytosol; HDA:TAIR.
DR GO; GO:0016459; C:myosin complex; ISS:TAIR.
DR GO; GO:0005777; C:peroxisome; IDA:TAIR.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.
DR GO; GO:0003774; F:cytoskeletal motor activity; ISS:TAIR.
DR GO; GO:0030742; F:GTP-dependent protein binding; IPI:TAIR.
DR GO; GO:0031267; F:small GTPase binding; IPI:TAIR.
DR GO; GO:0007015; P:actin filament organization; IEA:InterPro.
DR GO; GO:0030048; P:actin filament-based movement; TAS:TAIR.
DR GO; GO:0051645; P:Golgi localization; IMP:TAIR.
DR GO; GO:0048467; P:gynoecium development; IGI:TAIR.
DR GO; GO:0090436; P:leaf pavement cell development; IGI:TAIR.
DR GO; GO:0051646; P:mitochondrion localization; IMP:TAIR.
DR GO; GO:0060151; P:peroxisome localization; IMP:TAIR.
DR GO; GO:0048767; P:root hair elongation; IMP:TAIR.
DR GO; GO:0010090; P:trichome morphogenesis; IGI:TAIR.
DR CDD; cd15475; MyosinXI_CBD; 1.
DR CDD; cd01384; MYSc_Myo11; 1.
DR Gene3D; 1.10.10.820; -; 1.
DR Gene3D; 1.20.5.190; -; 3.
DR Gene3D; 1.20.58.530; -; 1.
DR Gene3D; 6.20.240.20; -; 1.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR Gene3D; 1.20.120.720; Myosin VI head, motor domain, U50 subdomain; 1.
DR InterPro; IPR002710; Dilute_dom.
DR InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR001609; Myosin_head_motor_dom.
DR InterPro; IPR004009; Myosin_N.
DR InterPro; IPR037975; MyosinXI_CBD.
DR InterPro; IPR036018; MYSc_Myo11.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR13140; MYOSIN; 1.
DR PANTHER; PTHR13140:SF836; MYOSIN-6; 1.
DR Pfam; PF01843; DIL; 1.
DR Pfam; PF00612; IQ; 6.
DR Pfam; PF00063; Myosin_head; 1.
DR Pfam; PF02736; Myosin_N; 1.
DR PRINTS; PR00193; MYOSINHEAVY.
DR SMART; SM01132; DIL; 1.
DR SMART; SM00015; IQ; 6.
DR SMART; SM00242; MYSc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51126; DILUTE; 1.
DR PROSITE; PS50096; IQ; 6.
DR PROSITE; PS51456; MYOSIN_MOTOR; 1.
DR PROSITE; PS51844; SH3_LIKE; 1.
PE 1: Evidence at protein level;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; Calmodulin-binding {ECO:0000256|ARBA:ARBA00022860};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Myosin {ECO:0000256|ARBA:ARBA00023123, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Proteomics identification {ECO:0007829|PeptideAtlas:F4K7C5,
KW ECO:0007829|ProteomicsDB:F4K7C5};
KW Reference proteome {ECO:0000313|Proteomes:UP000006548}.
FT DOMAIN 68..117
FT /note="Myosin N-terminal SH3-like"
FT /evidence="ECO:0000259|PROSITE:PS51844"
FT DOMAIN 122..791
FT /note="Myosin motor"
FT /evidence="ECO:0000259|PROSITE:PS51456"
FT DOMAIN 1208..1512
FT /note="Dilute"
FT /evidence="ECO:0000259|PROSITE:PS51126"
FT REGION 672..694
FT /note="Actin-binding"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
FT COILED 936..1107
FT /evidence="ECO:0000256|SAM:Coils"
FT BINDING 216..223
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
SQ SEQUENCE 1565 AA; 176864 MW; 282B0EEE9CE5C704 CRC64;
MFLDAAKSDS RFSVCVCDTV LLYVYHVNKT KSPQKVEESR EARKGKNKIQ KAEVFDLRNE
MVANFNPSVG SFVWVEDPDE AWIDGEVVQV NGDEIKVLCT SGKHVVTKIS NAYPKDVEAP
ASGVDDMTRL AYLHEPGVLQ NLHSRYDINE IYTYTGSILI AVNPFRRLPH LYSSHMMAQY
KGASLGELSP HPFAVADAAY RQMINDGVSQ SILVSGESGA GKTESTKLLM RYLAYMGGRA
AAEGRSVEQK VLESNPVLEA FGNAKTVRNN NSSRFGKFVE IQFDEKGRIS GAAIRTYLLE
RSRVCQVSDP ERNYHCFYML CAAPQEDVKK FKLEEPKKYH YLNQSKCLEL DSINDAEEYH
ATRRAMDVVG ISTEEQDAIF SVVAAILHIG NIEFAKGEEI DSSIPKDDKS LFHLKTAAEL
LSCDEKALED SLCKRIMVTR DETITKTLDP EAATLSRDAL AKVMYSRLFD WLVDKINSSI
GQDHDSKYLI GVLDIYGFES FKTNSFEQFC INLTNEKLQQ HFNQHVFKME QEEYKKEEIN
WSYIEFVDNQ DILDLIEKKP GGIIALLDEA CMFPRSTHET FAQKLYQTFK THKRFTKPKL
ARSDFTICHY AGDVTYQTEL FLDKNKDYVI AEHQALLNSS SCSFVASLFP PMSDDSKQSK
FSSIGTRFKQ QLVSLLEILN TTEPHYIRCI KPNNLLKPGI FENENILQQL RCGGVMEAIR
ISCAGYPTRK HFDEFLARFG ILAPEVLVKN SDDPAACKKL LDKVGLEGYQ IGKTKVFLRA
GQMADLDTRR TEVLGRSASI IQRKVRSYLA KKSFIVLRNS AKQIQSVCRG YLARSVYEGM
RREAAALKIQ RDLRRFLARK AYTELYSAAV SVQAGMRGMV ARKELCFRRQ TKAAIIIQTW
CRGYLARLHY RKLKKAAITT QCAWRSKVAR GELRKLKMAA RETGALQAAK NKLEKQVEEL
TWRLQLEKRI RTDLEEAKKQ ESAKAQSSLE ELQLKCKETE ALLIKEREAA KKIAETAPII
KEIPVVDQEL MDKITNENEK LKSMVSSLEM KIGETEKKLQ ETTKISQDRL NQALEAESKL
VKLKTAMQRL EEKILDMEAE KKIMHQQTIS TPVRTNLGHP PTAPVKNLEN GHQTNLEKEF
NEAEFTTPVD GKAGKSAAER QIMNVDALID CVKDNIGFSN GKPVAAFTIY KCLLHWKCFE
SEKTNVFDRL IQMIGSAIEN EDDNSHLAYW LTSTSALLFL LQKSLKTNGS GATQSKKPPA
STSLFGRMAM SFRSSPASGN LAAAAEAAAL AVVRPVEAKY PALLFKQQLA AYVEKMFGMV
RDNLKRELST LLSLCIQAPR SSKGGMLRSG RSFGKDSPAV HWQSIIDGLN SLLVTLKENH
VPLVLIQKIY SQTFSYINVQ LFNSLLLRKE CCTFSNGEFV KSGLAELELW CCQAKEYSGP
SWEELKHIRQ AVGFLVIHQK YRISYDEIAN DLCPVLSVQQ LYRICTLYWD DSYNTRSVSQ
EVISSMRTLM TEESNDADSD SFLLDDDSSI PFSIDDISSS MEEKDFVGIK PAEELLENPA
FVFLH
//
