ID F4K8X8_ARATH Unreviewed; 627 AA.
AC F4K8X8;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 24-JAN-2024, entry version 47.
DE SubName: Full=DNA repair protein RadA-like protein {ECO:0000313|EMBL:AED95929.2};
GN Name=ATRADA {ECO:0000313|TAIR:AT5G50340};
GN Synonyms=MXI22.5 {ECO:0000313|EMBL:AED95929.2}, MXI22_5
GN {ECO:0000313|EMBL:AED95929.2};
GN OrderedLocusNames=At5g50340 {ECO:0000313|Araport:AT5G50340,
GN ECO:0000313|EMBL:AED95929.2};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702 {ECO:0000313|EMBL:AED95929.2, ECO:0000313|Proteomes:UP000006548};
RN [1] {ECO:0000313|EMBL:AED95929.2, ECO:0000313|Proteomes:UP000006548}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia {ECO:0000313|Proteomes:UP000006548};
RX PubMed=11130714; DOI=10.1038/35048507;
RG Kazusa DNA Research Institute;
RG Cold Spring Harbor and Washington University in St Louis Sequencing Consortium;
RG European Union Arabidopsis Genome Sequencing Consortium;
RA Tabata S., Kaneko T., Nakamura Y., Kotani H., Kato T., Asamizu E.,
RA Miyajima N., Sasamoto S., Kimura T., Hosouchi T., Kawashima K., Kohara M.,
RA Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Naruo K.,
RA Okumura S., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M.,
RA Yasuda M., Sato S., de la Bastide M., Huang E., Spiegel L., Gnoj L.,
RA O'Shaughnessy A., Preston R., Habermann K., Murray J., Johnson D.,
RA Rohlfing T., Nelson J., Stoneking T., Pepin K., Spieth J., Sekhon M.,
RA Armstrong J., Becker M., Belter E., Cordum H., Cordes M., Courtney L.,
RA Courtney W., Dante M., Du H., Edwards J., Fryman J., Haakensen B.,
RA Lamar E., Latreille P., Leonard S., Meyer R., Mulvaney E., Ozersky P.,
RA Riley A., Strowmatt C., Wagner-McPherson C., Wollam A., Yoakum M., Bell M.,
RA Dedhia N., Parnell L., Shah R., Rodriguez M., See L.H., Vil D., Baker J.,
RA Kirchoff K., Toth K., King L., Bahret A., Miller B., Marra M.,
RA Martienssen R., McCombie W.R., Wilson R.K., Murphy G., Bancroft I.,
RA Volckaert G., Wambutt R., Dusterhoft A., Stiekema W., Pohl T., Entian K.D.,
RA Terryn N., Hartley N., Bent E., Johnson S., Langham S.A., McCullagh B.,
RA Robben J., Grymonprez B., Zimmermann W., Ramsperger U., Wedler H.,
RA Balke K., Wedler E., Peters S., van Staveren M., Dirkse W., Mooijman P.,
RA Lankhorst R.K., Weitzenegger T., Bothe G., Rose M., Hauf J., Berneiser S.,
RA Hempel S., Feldpausch M., Lamberth S., Villarroel R., Gielen J.,
RA Ardiles W., Bents O., Lemcke K., Kolesov G., Mayer K., Rudd S., Schoof H.,
RA Schueller C., Zaccaria P., Mewes H.W., Bevan M., Fransz P.;
RT "Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana.";
RL Nature 408:823-826(2000).
RN [2] {ECO:0000313|EMBL:AED95929.2}
RP NUCLEOTIDE SEQUENCE.
RG TAIR;
RA Swarbreck D., Lamesch P., Wilks C., Huala E.;
RL Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:AED95929.2}
RP NUCLEOTIDE SEQUENCE.
RA Krishnakumar V., Cheng C.-Y., Chan A.P., Schobel S., Kim M., Ferlanti E.S.,
RA Belyaeva I., Rosen B.D., Micklem G., Miller J.R., Vaughn M., Town C.D.;
RL Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|Proteomes:UP000006548}
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia {ECO:0000313|Proteomes:UP000006548};
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
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DR EMBL; CP002688; AED95929.2; -; Genomic_DNA.
DR EMBL; CP002688; ANM71053.1; -; Genomic_DNA.
DR RefSeq; NP_001318773.1; NM_001344887.1.
DR RefSeq; NP_001332610.1; NM_001344888.1.
DR AlphaFoldDB; F4K8X8; -.
DR SMR; F4K8X8; -.
DR STRING; 3702.F4K8X8; -.
DR PaxDb; 3702-AT5G50340-1; -.
DR ProteomicsDB; 179704; -.
DR EnsemblPlants; AT5G50340.1; AT5G50340.1; AT5G50340.
DR EnsemblPlants; AT5G50340.3; AT5G50340.3; AT5G50340.
DR GeneID; 835101; -.
DR Gramene; AT5G50340.1; AT5G50340.1; AT5G50340.
DR Gramene; AT5G50340.3; AT5G50340.3; AT5G50340.
DR KEGG; ath:AT5G50340; -.
DR Araport; AT5G50340; -.
DR TAIR; AT5G50340; ATRADA.
DR eggNOG; ENOG502QQ01; Eukaryota.
DR OrthoDB; 36031at2759; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; F4K8X8; baseline and differential.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR GO; GO:0003684; F:damaged DNA binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0000725; P:recombinational repair; IBA:GO_Central.
DR CDD; cd01121; RadA_SMS_N; 1.
DR Gene3D; 3.30.230.10; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR004504; DNA_repair_RadA.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR020588; RecA_ATP-bd.
DR InterPro; IPR020568; Ribosomal_Su5_D2-typ_SF.
DR InterPro; IPR014721; Ribsml_uS5_D2-typ_fold_subgr.
DR InterPro; IPR041166; Rubredoxin_2.
DR NCBIfam; TIGR00416; sms; 1.
DR PANTHER; PTHR32472; DNA REPAIR PROTEIN RADA; 1.
DR PANTHER; PTHR32472:SF10; DNA REPAIR PROTEIN RADA-LIKE PROTEIN; 1.
DR Pfam; PF13481; AAA_25; 1.
DR Pfam; PF13541; ChlI; 1.
DR Pfam; PF18073; Rubredoxin_2; 1.
DR PRINTS; PR01874; DNAREPAIRADA.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF54211; Ribosomal protein S5 domain 2-like; 1.
DR PROSITE; PS50162; RECA_2; 1.
PE 1: Evidence at protein level;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Proteomics identification {ECO:0007829|PeptideAtlas:F4K8X8,
KW ECO:0007829|ProteomicsDB:F4K8X8};
KW Reference proteome {ECO:0000313|Proteomes:UP000006548};
KW Stress response {ECO:0000256|ARBA:ARBA00023016};
KW Zinc {ECO:0000256|ARBA:ARBA00022771};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 230..384
FT /note="RecA family profile 1"
FT /evidence="ECO:0000259|PROSITE:PS50162"
FT REGION 98..141
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 178..200
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 101..124
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 627 AA; 67646 MW; 75623E3362175D7C CRC64;
MLSQKKTERQ SRVCEIGGFR TSELRTLTSN SGERFLSLLL MLIADMRCFR CFYTRAHSLL
LLRSSNPVTV PISPVRFRLR LRRLSSSPVA SVFDLHSSNQ DANSNREDKD TKIGFSDDKS
RKSGSNPPRW NPGEVVMNKS KKGKSKTVWV CESCGHSEGQ WWGSCRACHK VGTMKRFSEG
SESSASGGGG NGTGLGFTEG KGLSWLPEQA TVQPHRLTDV IHGITQQQWR ISLPGLFGNE
VARVLGGGLA PGSLILIGGD PGIGKSTLLL QIASIIAEGS ELAEPAPVLY ISGEESVEQI
GSRADRMRIQ TEELYLFSSS DLQDILNKAH RLSPRALIID SIQTVYLKDV TGSAGGLTQV
KECTSTLLRF AKKSNIPVFL VGHVTKAGDI AGPRVLEHIV DVVLYLEGEE SSTYRLLRSV
KNRFGSTDEL GVFEMANSGL EVVSNPSGIY LSQQNPDSDV LAGLAVAVVM DGSRSFLIEV
QALCSPGSTV SRHVNGVQAS RADMIIAVLM KQAGLRIQEN GIFLNVANGM ALSETAGDLA
IAAAICSSFL EFPIPHGVAF IGEIGLGGEV RTVPRMEKRV STVAKLGFNK CVVPKSVEES
LKALSLKEIE IIGCKNLKEL INAVFKG
//
