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Database: UniProt
Entry: F4L6E4_HALH1
LinkDB: F4L6E4_HALH1
Original site: F4L6E4_HALH1 
ID   F4L6E4_HALH1            Unreviewed;       362 AA.
AC   F4L6E4;
DT   28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT   28-JUN-2011, sequence version 1.
DT   26-FEB-2020, entry version 38.
DE   SubName: Full=Naringenin-chalcone synthase {ECO:0000313|EMBL:AEE48826.1};
DE            EC=2.3.1.74 {ECO:0000313|EMBL:AEE48826.1};
GN   OrderedLocusNames=Halhy_0925 {ECO:0000313|EMBL:AEE48826.1};
OS   Haliscomenobacter hydrossis (strain ATCC 27775 / DSM 1100 / LMG 10767 / O).
OC   Bacteria; Bacteroidetes; Saprospiria; Saprospirales;
OC   Haliscomenobacteraceae; Haliscomenobacter.
OX   NCBI_TaxID=760192 {ECO:0000313|EMBL:AEE48826.1, ECO:0000313|Proteomes:UP000008461};
RN   [1] {ECO:0000313|EMBL:AEE48826.1, ECO:0000313|Proteomes:UP000008461}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 27775 / DSM 1100 / LMG 10767 / O
RC   {ECO:0000313|Proteomes:UP000008461};
RX   PubMed=21886862; DOI=10.4056/sigs.1964579;
RG   US DOE Joint Genome Institute (JGI-PGF);
RA   Daligault H., Lapidus A., Zeytun A., Nolan M., Lucas S., Del Rio T.G.,
RA   Tice H., Cheng J.F., Tapia R., Han C., Goodwin L., Pitluck S., Liolios K.,
RA   Pagani I., Ivanova N., Huntemann M., Mavromatis K., Mikhailova N., Pati A.,
RA   Chen A., Palaniappan K., Land M., Hauser L., Brambilla E.M., Rohde M.,
RA   Verbarg S., Goker M., Bristow J., Eisen J.A., Markowitz V., Hugenholtz P.,
RA   Kyrpides N.C., Klenk H.P., Woyke T.;
RT   "Complete genome sequence of Haliscomenobacter hydrossis type strain (O).";
RL   Stand. Genomic Sci. 4:352-360(2011).
RN   [2]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=DSM 1100;
RG   US DOE Joint Genome Institute (JGI-PGF);
RA   Lucas S., Han J., Lapidus A., Bruce D., Goodwin L., Pitluck S., Peters L.,
RA   Kyrpides N., Mavromatis K., Ivanova N., Ovchinnikova G., Pagani I.,
RA   Daligault H., Detter J.C., Han C., Land M., Hauser L., Markowitz V.,
RA   Cheng J.-F., Hugenholtz P., Woyke T., Wu D., Verbarg S., Frueling A.,
RA   Brambilla E., Klenk H.-P., Eisen J.A.;
RT   "Complete sequence of chromosome of Haliscomenobacter hydrossis DSM 1100.";
RL   Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CP002691; AEE48826.1; -; Genomic_DNA.
DR   STRING; 760192.Halhy_0925; -.
DR   EnsemblBacteria; AEE48826; AEE48826; Halhy_0925.
DR   KEGG; hhy:Halhy_0925; -.
DR   eggNOG; ENOG41065KQ; Bacteria.
DR   eggNOG; COG3424; LUCA.
DR   HOGENOM; CLU_034992_0_2_10; -.
DR   OMA; CVRSWGG; -.
DR   BioCyc; HHYD760192:G1GXE-937-MONOMER; -.
DR   Proteomes; UP000008461; Chromosome.
DR   GO; GO:0016210; F:naringenin-chalcone synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR   Gene3D; 3.40.47.10; -; 2.
DR   InterPro; IPR012328; Chalcone/stilbene_synth_C.
DR   InterPro; IPR001099; Chalcone/stilbene_synthase_N.
DR   InterPro; IPR011141; Polyketide_synthase_type-III.
DR   InterPro; IPR016039; Thiolase-like.
DR   PANTHER; PTHR11877; PTHR11877; 1.
DR   Pfam; PF02797; Chal_sti_synt_C; 1.
DR   Pfam; PF00195; Chal_sti_synt_N; 1.
DR   PIRSF; PIRSF000451; PKS_III; 1.
DR   SUPFAM; SSF53901; SSF53901; 1.
PE   4: Predicted;
KW   Acyltransferase {ECO:0000313|EMBL:AEE48826.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008461};
KW   Transferase {ECO:0000313|EMBL:AEE48826.1}.
FT   DOMAIN          4..213
FT                   /note="Chal_sti_synt_N"
FT                   /evidence="ECO:0000259|Pfam:PF00195"
FT   DOMAIN          232..359
FT                   /note="Chal_sti_synt_C"
FT                   /evidence="ECO:0000259|Pfam:PF02797"
FT   ACT_SITE        151
FT                   /evidence="ECO:0000256|PIRSR:PIRSR000451-1"
SQ   SEQUENCE   362 AA;  39363 MW;  4716638C7D38F846 CRC64;
     MSYIVNIATA VPDHGYEQHV LTQFYSNSID DVSVKRKVKI LADKSGTSTR YSVLEDYGLP
     AEQFTFFPKN TQLLPSPGLT QRMDRFKKEA LPLSVKAIQN LPDFAASKSS ITHLITVTCT
     GLSAPGLDIE LMQALALPPT THRSSVNFLG CNAAIIALKQ ADGICKSQPD ALVLVVCTEL
     CTLHFQTIYN QDYLLCNVLF GDGSAAVLLS SQPVKESTSR NVQITGFDSF CIPDSRNEMA
     WQLSETGFIM NLSAYVGDLI KNNIKSMLDN VGIDPLSIDY WAVHPGGKKI VDSFGEALGL
     SVTDLAASYQ VLKDYGNMSS PTVLFVLKNI LENLDPHPDG KNIFAAAFGP GLTVETMQLC
     HA
//
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