ID F4LKR3_TREBD Unreviewed; 338 AA.
AC F4LKR3;
DT 28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT 28-JUN-2011, sequence version 1.
DT 27-MAR-2024, entry version 67.
DE SubName: Full=Transcriptional regulator, LacI family {ECO:0000313|EMBL:AEE15524.1};
GN OrderedLocusNames=Trebr_0066 {ECO:0000313|EMBL:AEE15524.1};
OS Treponema brennaborense (strain DSM 12168 / CIP 105900 / DD5/3).
OC Bacteria; Spirochaetota; Spirochaetia; Spirochaetales; Treponemataceae;
OC Treponema.
OX NCBI_TaxID=906968 {ECO:0000313|EMBL:AEE15524.1, ECO:0000313|Proteomes:UP000006546};
RN [1] {ECO:0000313|Proteomes:UP000006546}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 12168 / CIP 105900 / DD5/3
RC {ECO:0000313|Proteomes:UP000006546};
RA Lucas S., Han J., Lapidus A., Bruce D., Goodwin L., Pitluck S., Peters L.,
RA Kyrpides N., Mavromatis K., Ivanova N., Mikhailova N., Pagani I.,
RA Teshima H., Detter J.C., Tapia R., Han C., Land M., Hauser L.,
RA Markowitz V., Cheng J.-F., Hugenholtz P., Woyke T., Wu D., Gronow S.,
RA Wellnitz S., Brambilla E., Klenk H.-P., Eisen J.A.;
RT "The complete genome of Treponema brennaborense DSM 12168.";
RL Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP002696; AEE15524.1; -; Genomic_DNA.
DR RefSeq; WP_013757244.1; NC_015500.1.
DR AlphaFoldDB; F4LKR3; -.
DR STRING; 906968.Trebr_0066; -.
DR KEGG; tbe:Trebr_0066; -.
DR eggNOG; COG1609; Bacteria.
DR HOGENOM; CLU_037628_6_1_12; -.
DR OrthoDB; 367059at2; -.
DR Proteomes; UP000006546; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd01392; HTH_LacI; 1.
DR CDD; cd06267; PBP1_LacI_sugar_binding-like; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR InterPro; IPR000843; HTH_LacI.
DR InterPro; IPR046335; LacI/GalR-like_sensor.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR30146:SF152; HTH-TYPE TRANSCRIPTIONAL REGULATOR EBGR-RELATED; 1.
DR PANTHER; PTHR30146; LACI-RELATED TRANSCRIPTIONAL REPRESSOR; 1.
DR Pfam; PF00356; LacI; 1.
DR Pfam; PF13377; Peripla_BP_3; 1.
DR PRINTS; PR00036; HTHLACI.
DR SMART; SM00354; HTH_LACI; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS00356; HTH_LACI_1; 1.
DR PROSITE; PS50932; HTH_LACI_2; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Membrane {ECO:0000256|ARBA:ARBA00022475};
KW Reference proteome {ECO:0000313|Proteomes:UP000006546};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 2..56
FT /note="HTH lacI-type"
FT /evidence="ECO:0000259|PROSITE:PS50932"
SQ SEQUENCE 338 AA; 37748 MW; F6D721BDC3B6759E CRC64;
MLNIKDIAKL ADVSISTVSR VINKTAYVNP ETERRVRKIL NETGYTPSLQ AREMQQKRTH
TIGIIIPRID LETFSAVFDG ISHVLSERKY SVLLADTHVD LEKELEYLDV FCKKRVDGIL
YFVVGTSETQ RRIVSRLPVP VVILDQSGIA FNRPAVRKDS FAGAKDIVTY LCSLGHRRIG
CLCADSTDYS SSVLRRHGYE AALTEQGIPS DQELIVAGTF EYSSGYEGTE KLMLRGDAAP
TAIFCITDRL AIACCSWLLS HGYRIPQDVS VACVDDTSLL KYCYPGVTTM SLNYELMGNT
AARMILECIE ENEKERKEIV FPYTLTVRGS TGEVKTDT
//
