ID F4NSE8_BATDJ Unreviewed; 2023 AA.
AC F4NSE8;
DT 28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT 28-JUN-2011, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE RecName: Full=FH2 domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=BATDEDRAFT_34176 {ECO:0000313|EMBL:EGF84247.1};
OS Batrachochytrium dendrobatidis (strain JAM81 / FGSC 10211) (Frog chytrid
OS fungus).
OC Eukaryota; Fungi; Fungi incertae sedis; Chytridiomycota;
OC Chytridiomycota incertae sedis; Chytridiomycetes; Rhizophydiales;
OC Rhizophydiales incertae sedis; Batrachochytrium.
OX NCBI_TaxID=684364 {ECO:0000313|EMBL:EGF84247.1, ECO:0000313|Proteomes:UP000007241};
RN [1] {ECO:0000313|EMBL:EGF84247.1, ECO:0000313|Proteomes:UP000007241}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JAM81 / FGSC 10211 {ECO:0000313|Proteomes:UP000007241};
RG US DOE Joint Genome Institute (JGI-PGF);
RA Kuo A., Salamov A., Schmutz J., Lucas S., Pitluck S., Rosenblum E.,
RA Stajich J., Eisen M., Grigoriev I.V.;
RT "The draft genome of Batrachochytrium dendrobatidis.";
RL Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; GL882879; EGF84247.1; -; Genomic_DNA.
DR RefSeq; XP_006675776.1; XM_006675713.1.
DR STRING; 684364.F4NSE8; -.
DR GeneID; 18240348; -.
DR HOGENOM; CLU_233542_0_0_1; -.
DR InParanoid; F4NSE8; -.
DR OrthoDB; 1331417at2759; -.
DR Proteomes; UP000007241; Unassembled WGS sequence.
DR GO; GO:0003779; F:actin binding; IEA:InterPro.
DR GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR GO; GO:0030036; P:actin cytoskeleton organization; IEA:InterPro.
DR Gene3D; 1.20.58.2220; Formin, FH2 domain; 1.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR015425; FH2_Formin.
DR InterPro; IPR042201; FH2_Formin_sf.
DR InterPro; IPR010472; FH3_dom.
DR InterPro; IPR014768; GBD/FH3_dom.
DR InterPro; IPR010473; GTPase-bd.
DR PANTHER; PTHR45725:SF1; DELPHILIN; 1.
DR PANTHER; PTHR45725; FORMIN HOMOLOGY 2 FAMILY MEMBER; 1.
DR Pfam; PF06367; Drf_FH3; 1.
DR Pfam; PF02181; FH2; 1.
DR SMART; SM01139; Drf_FH3; 1.
DR SMART; SM01140; Drf_GBD; 1.
DR SMART; SM00498; FH2; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF101447; Formin homology 2 domain (FH2 domain); 1.
DR PROSITE; PS51444; FH2; 1.
DR PROSITE; PS51232; GBD_FH3; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000007241}.
FT DOMAIN 380..838
FT /note="GBD/FH3"
FT /evidence="ECO:0000259|PROSITE:PS51232"
FT DOMAIN 1346..1747
FT /note="FH2"
FT /evidence="ECO:0000259|PROSITE:PS51444"
FT REGION 123..177
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 333..363
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 409..431
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1250..1343
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 932..962
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 333..349
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1250..1267
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1274..1303
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1306..1342
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2023 AA; 226190 MW; 5DA99C616E80670D CRC64;
MHSRKDQADN KGSFLQGRTN KLKNTASFSS LRKPFFGFGQ SSSSTPSGSS ISEQVSSASL
YSTASATSDL QRPQSILHMN SEFEVMMDDR RIPEDQRHQL RNLPLKSREF LLTNWRKLVG
LSNTPSRSSS IPATSSSISA ARSSNHSATS SVLQPSDQST SSNLQNNNTQ KSSATSTSQK
QISLLFNDIL DALNYNGARR LSMLALSDSK KLHFIRQYHR RQELEQEQSR KNKFLPKIIA
RKTSLLFSSP TMRPVECLND TELESVFAQN EMGLQGSART NLAFKSNSYK REIIAKYQMQ
QQLQIGVGSD FNQQHTPASF PISDPVNLSF KNKLRSTTRS TQSDTKSGLV EGRATALPAP
QVSQATPLST LQSQYLPFKK HASFEKPLPI PFEKPLPIPS SPTLDVRLTR QSRVSSKAAS
PTGSLLNANR QSNQFTENSA EWFVIQISNR NATLKALFRL LSSLRVTLSL GGSSFNDKFL
LCRITLDNSN IIGGVESLEI AMDRITEILS PTLRQSFNTI LFQQRLDSNV GVKVRSGFTQ
SIYADAVLGD ELRHEVVQCI RLLLNSKVGV GALVNSMALL RQTVWCLALP SPELRDGVLN
NFQQRRAFLA LRSLVSETLA PLCLLSDVGR KLILQALLEL SQIQDEPAPF QNLILSIDNP
FCFGDKAAKR DSNGFEELID EVELWDYRTS IVVLINSLVS AAEQPTERWG VRRLVESRGV
RSILQTLLNL RGCTATFRVQ VDAYEQDRKA DIEEIEKIYK DCTRTFSNPQ DTLSNLLKSA
QSLPDPERST YLVMATLDNF SQILNSLKPI DDSETQINSS ARKQGFIYGD GMDRRGSHNS
NIDQDLHTRE KSSYALTALE KSTRAMAGSV LNWRSPQNSF SEPIAPEMQA RRCFELLNND
VIRVFEDLSN PYPRKATPHS TTDEEELRVL GNTNLTGVIQ ELNSLKKQLR ETLSLLDIQK
KQNIFLKRSL ERAKATPTGN ADFELGFEDS LSQTDSQNKA SGSIERAFLT RNSKAGQEEF
INNQFISPTD ASSHSRLAKE RSWTLKASKN EGPFLKRTTS HSLQFQQHDP SVDTNDLKFS
EKDSAALHPP VIRIDSEADL QDIVLEKGQT HFEYSGKHIV LGPSGTIIQS RRFKPFLDET
RFKKVSVDGV VGDANRSSEG NSEIYDYSST ETTEARELIG MIRAQQQLES QYQTNQDTSS
ASDIRVQHTW NRLGKTAGVG KLWEEIQRLE RQVDELRGVN EKLEIETQSS IGHQQLKQKS
LAESTETSND AIDKDDSSSS SVNQLTSTAT YSNTDQDLED QTLVINATPP PPPPPPPPLS
GPPPPPPPPL SGPPPPPSGL APPQQNLLIL QAKNPMKHLQ WDKIANHIAV QSIWKDLFTE
TYSKDIDLEE DELLELFSKI DEAKTVQSSK PLEAKKVITL LDHKRAQDIA ITLKGLRLPF
ASISLAIKTI DDDALSIDQL SKLCKYAPKE DELDILKSYE GDLSELGDAE TYFIALMDIP
RIEMRMNSMI FRRRFNDEID EITTDCSTLL LACDQILKSN LLRELLQAVL IIGNYLNGTS
FRGNARGFRL ESLMTLRDTK ANNGKAVGTL LHYLAQYLQK NQQHVLEYMS DMPSVEAASR
VSFNSLEDSI RQLRSGWQSI QLELETYKSQ GFPKDTQDRF LDCFDTFLSK TKTPLDTAEE
TVKELRIKLD QVFHYFAEDV SDRMRSPEKF FDIFPTFSRN LQRALREYNA TCRSIANKKK
LFIKAEAQKA IIARKRSSQA SFKNLAPTNY AKSTPLTLQT GMANTFLMPD SAEMTASARF
TMENGPRSTF MTAVPPPVDG MSNLRSIDGP DTLVKGFFGF NNKDNELSVR ADSLDEFADN
LLKQAALEEM QERMQDIHDT AHSSLDLDDA DLLPVQHSDS FEEESLPVII DDSNYSSPRI
STFENLLGIP HESSFHSIAS DEASISEIYS SLQQDDMDSD TLEESGEGSI AVSSLLLHGG
SMANARNTIK RVKKHLSSST VYHIDESMPT QLEVESDTGF TAL
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