ID   F4NWE6_BATDJ            Unreviewed;       493 AA.
AC   F4NWE6;
DT   28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT   28-JUN-2011, sequence version 1.
DT   27-MAR-2024, entry version 42.
DE   RecName: Full=Tyrosinase copper-binding domain-containing protein {ECO:0000259|PROSITE:PS00497, ECO:0000259|PROSITE:PS00498};
GN   ORFNames=BATDEDRAFT_86650 {ECO:0000313|EMBL:EGF82465.1};
OS   Batrachochytrium dendrobatidis (strain JAM81 / FGSC 10211) (Frog chytrid
OS   fungus).
OC   Eukaryota; Fungi; Fungi incertae sedis; Chytridiomycota;
OC   Chytridiomycota incertae sedis; Chytridiomycetes; Rhizophydiales;
OC   Rhizophydiales incertae sedis; Batrachochytrium.
OX   NCBI_TaxID=684364 {ECO:0000313|EMBL:EGF82465.1, ECO:0000313|Proteomes:UP000007241};
RN   [1] {ECO:0000313|EMBL:EGF82465.1, ECO:0000313|Proteomes:UP000007241}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JAM81 / FGSC 10211 {ECO:0000313|Proteomes:UP000007241};
RG   US DOE Joint Genome Institute (JGI-PGF);
RA   Kuo A., Salamov A., Schmutz J., Lucas S., Pitluck S., Rosenblum E.,
RA   Stajich J., Eisen M., Grigoriev I.V.;
RT   "The draft genome of Batrachochytrium dendrobatidis.";
RL   Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Cu(2+); Xref=ChEBI:CHEBI:29036;
CC         Evidence={ECO:0000256|ARBA:ARBA00001973};
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DR   EMBL; GL882880; EGF82465.1; -; Genomic_DNA.
DR   RefSeq; XP_006676933.1; XM_006676870.1.
DR   AlphaFoldDB; F4NWE6; -.
DR   GeneID; 18242527; -.
DR   HOGENOM; CLU_553190_0_0_1; -.
DR   InParanoid; F4NWE6; -.
DR   OrthoDB; 4070889at2759; -.
DR   Proteomes; UP000007241; Unassembled WGS sequence.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   Gene3D; 1.10.1280.10; Di-copper center containing domain from catechol oxidase; 1.
DR   InterPro; IPR008922; Di-copper_centre_dom_sf.
DR   InterPro; IPR002227; Tyrosinase_Cu-bd.
DR   PANTHER; PTHR11474:SF124; TYROSINASE; 1.
DR   PANTHER; PTHR11474; TYROSINASE FAMILY MEMBER; 1.
DR   Pfam; PF00264; Tyrosinase; 1.
DR   PRINTS; PR00092; TYROSINASE.
DR   SUPFAM; SSF48056; Di-copper centre-containing domain; 1.
DR   PROSITE; PS00497; TYROSINASE_1; 1.
DR   PROSITE; PS00498; TYROSINASE_2; 1.
PE   4: Predicted;
KW   Copper {ECO:0000256|ARBA:ARBA00023008};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007241}.
FT   DOMAIN          82..99
FT                   /note="Tyrosinase copper-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS00497"
FT   DOMAIN          224..235
FT                   /note="Tyrosinase copper-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS00498"
FT   REGION          294..325
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   493 AA;  54578 MW;  7DC459617F741356 CRC64;
     MRIIETMAAF ATFAIGFQNS LVVAQCSRTT VRKELYDMNE RDWTIYTETI RKATMMPDPN
     GSGYSIWEAG AQLHNRVASM IHGNCQFLFW HRMFMSWTER RLQAINPEFS FFYWDSASEW
     SAPTNSIIWK YLGRSGRPVR DGFLSDVSFR STNGPLIRNF QFPNLGGILP STDTYSQMYT
     DSIANGGFAF YAPRLELYHG QVHVLIGGGP MEDGQMQSML SPLDPFFFAH HGHIDWMWFN
     AQAGWANYRP DSAYQIGGLD HMNMTCSLNS PLSGFQGVLA DVLDLRSLCV QYSNPRAGGN
     RPPPQPGFSQ PLPNDPMQSG GGFNTGFSAP PGGFNTGLSV PPGGNMGSGA FQQFVQPFQP
     PAGYTPMNQC PQNLPAQWLS MNFRNPNAIT LCESIRVRCE ELRIQIASGR QVNPFQVLID
     APGRPLISQV VPFSASGAQP MNVPLVPTID QSYYPHGGSI ITSKATSRLG EYGIDHIILI
     FSSILAVTGF ITL
//