ID   F4NZJ9_BATDJ            Unreviewed;       795 AA.
AC   F4NZJ9;
DT   28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT   28-JUN-2011, sequence version 1.
DT   27-MAR-2024, entry version 60.
DE   RecName: Full=Cullin family profile domain-containing protein {ECO:0000259|PROSITE:PS50069};
GN   ORFNames=BATDEDRAFT_19177 {ECO:0000313|EMBL:EGF81454.1};
OS   Batrachochytrium dendrobatidis (strain JAM81 / FGSC 10211) (Frog chytrid
OS   fungus).
OC   Eukaryota; Fungi; Fungi incertae sedis; Chytridiomycota;
OC   Chytridiomycota incertae sedis; Chytridiomycetes; Rhizophydiales;
OC   Rhizophydiales incertae sedis; Batrachochytrium.
OX   NCBI_TaxID=684364 {ECO:0000313|EMBL:EGF81454.1, ECO:0000313|Proteomes:UP000007241};
RN   [1] {ECO:0000313|EMBL:EGF81454.1, ECO:0000313|Proteomes:UP000007241}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JAM81 / FGSC 10211 {ECO:0000313|Proteomes:UP000007241};
RG   US DOE Joint Genome Institute (JGI-PGF);
RA   Kuo A., Salamov A., Schmutz J., Lucas S., Pitluck S., Rosenblum E.,
RA   Stajich J., Eisen M., Grigoriev I.V.;
RT   "The draft genome of Batrachochytrium dendrobatidis.";
RL   Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the cullin family.
CC       {ECO:0000256|ARBA:ARBA00006019, ECO:0000256|PROSITE-ProRule:PRU00330,
CC       ECO:0000256|RuleBase:RU003829}.
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DR   EMBL; GL882882; EGF81454.1; -; Genomic_DNA.
DR   RefSeq; XP_006677802.1; XM_006677739.1.
DR   AlphaFoldDB; F4NZJ9; -.
DR   STRING; 684364.F4NZJ9; -.
DR   GeneID; 18237366; -.
DR   HOGENOM; CLU_004747_7_2_1; -.
DR   InParanoid; F4NZJ9; -.
DR   OMA; NYQEQTW; -.
DR   OrthoDB; 5474206at2759; -.
DR   Proteomes; UP000007241; Unassembled WGS sequence.
DR   GO; GO:0080008; C:Cul4-RING E3 ubiquitin ligase complex; IBA:GO_Central.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IBA:GO_Central.
DR   GO; GO:0006974; P:DNA damage response; IBA:GO_Central.
DR   GO; GO:0016567; P:protein ubiquitination; IBA:GO_Central.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
DR   Gene3D; 1.20.1310.10; Cullin Repeats; 4.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR045093; Cullin.
DR   InterPro; IPR016157; Cullin_CS.
DR   InterPro; IPR016158; Cullin_homology.
DR   InterPro; IPR036317; Cullin_homology_sf.
DR   InterPro; IPR001373; Cullin_N.
DR   InterPro; IPR019559; Cullin_neddylation_domain.
DR   InterPro; IPR016159; Cullin_repeat-like_dom_sf.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR11932; CULLIN; 1.
DR   PANTHER; PTHR11932:SF126; CULLIN 4, ISOFORM A; 1.
DR   Pfam; PF00888; Cullin; 1.
DR   Pfam; PF10557; Cullin_Nedd8; 1.
DR   SMART; SM00182; CULLIN; 1.
DR   SMART; SM00884; Cullin_Nedd8; 1.
DR   SUPFAM; SSF75632; Cullin homology domain; 1.
DR   SUPFAM; SSF74788; Cullin repeat-like; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS01256; CULLIN_1; 1.
DR   PROSITE; PS50069; CULLIN_2; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000007241};
KW   Ubl conjugation {ECO:0000256|ARBA:ARBA00022843}.
FT   DOMAIN          442..668
FT                   /note="Cullin family profile"
FT                   /evidence="ECO:0000259|PROSITE:PS50069"
FT   REGION          1..59
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        7..27
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        37..59
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   795 AA;  92441 MW;  9F01A19519A148EE CRC64;
     MLPTAGPQRQ HPQQTSQQQG TNLPKPDTRH SSNKRPKLET PFTMLNANND ADQKQSQRLG
     GKTAKKLVIK SFKVKPKLPE NFEADTWEKL RLAVQAIHAR QPVQDSLEEL YKACENLCHH
     NRQSNLYQKL YSVCKDHVLV ELDALKSNIH TSGCNILVAV NECWLRYCQQ MMLIRSIFLY
     LDRTYVLQTA SLKSIWSMSM DLFRSYVLDD KEIQERVVRE LIQEINCERR EQQISRPLMR
     SLIRMMTDLS VYIRVFETTF LENTRQFYRV FSKTIVDSID GNLALGEGAN RVSSYLIQVS
     NRLEQETQRC SPGEGYIDPL TRKKLVLTLE DELLRQHATL LLDVGFDQLV AAQRIDDLAL
     FYKLLERIGM LEELKRRMSQ YIQATGIFIV KDPTRDKTMV QELLEFKMRL DDILKNAFQS
     TESFDHAIKE SFEKFINQRQ NKPAEMIAKY IDELLKHVKG MTDLEVDRRL DQCLAIFRLV
     QGKDVFEAFY SKDLAKRLLL EKSTSVDAEK SMLFKLKAEC GPGFTSKLEG MFKDMELSRD
     IKRKFEDTAG FYNRIGRIDL NVYVLTSGLW PTYTPVDLNL PNEMTVCQEV FKEYYMSKHN
     GRRLVWHNSL GSCILRAQFE KPKELQLSLF QAVIMLCFNN SKTLSFNALH TLTNLDEKEL
     SRTLQSLSVG KSRVLLKESK GKDVELDDTF EVNEHFTHPQ YRIKIGSISV RESVDEMVET
     NEKVFQDRVF QVDAAIVRIM KTEKRCAHAT LVSKLFQIVK FPIAAEDLKK RIESLIEREY
     LDRDSNDKSL YIYLA
//