ID F4P9X9_BATDJ Unreviewed; 826 AA.
AC F4P9X9;
DT 28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT 28-JUN-2011, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE RecName: Full=HRDC domain-containing protein {ECO:0000259|PROSITE:PS50967};
GN ORFNames=BATDEDRAFT_27210 {ECO:0000313|EMBL:EGF78021.1};
OS Batrachochytrium dendrobatidis (strain JAM81 / FGSC 10211) (Frog chytrid
OS fungus).
OC Eukaryota; Fungi; Fungi incertae sedis; Chytridiomycota;
OC Chytridiomycota incertae sedis; Chytridiomycetes; Rhizophydiales;
OC Rhizophydiales incertae sedis; Batrachochytrium.
OX NCBI_TaxID=684364 {ECO:0000313|EMBL:EGF78021.1, ECO:0000313|Proteomes:UP000007241};
RN [1] {ECO:0000313|EMBL:EGF78021.1, ECO:0000313|Proteomes:UP000007241}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JAM81 / FGSC 10211 {ECO:0000313|Proteomes:UP000007241};
RG US DOE Joint Genome Institute (JGI-PGF);
RA Kuo A., Salamov A., Schmutz J., Lucas S., Pitluck S., Rosenblum E.,
RA Stajich J., Eisen M., Grigoriev I.V.;
RT "The draft genome of Batrachochytrium dendrobatidis.";
RL Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the exosome component 10/RRP6 family.
CC {ECO:0000256|ARBA:ARBA00043957}.
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DR EMBL; GL882890; EGF78021.1; -; Genomic_DNA.
DR RefSeq; XP_006681407.1; XM_006681344.1.
DR AlphaFoldDB; F4P9X9; -.
DR STRING; 684364.F4P9X9; -.
DR GeneID; 18239258; -.
DR HOGENOM; CLU_010129_3_2_1; -.
DR InParanoid; F4P9X9; -.
DR OMA; TMDIIWL; -.
DR OrthoDB; 2880475at2759; -.
DR Proteomes; UP000007241; Unassembled WGS sequence.
DR GO; GO:0000176; C:nuclear exosome (RNase complex); IBA:GO_Central.
DR GO; GO:0005730; C:nucleolus; IBA:GO_Central.
DR GO; GO:0000175; F:3'-5'-RNA exonuclease activity; IBA:GO_Central.
DR GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR GO; GO:0003727; F:single-stranded RNA binding; IBA:GO_Central.
DR GO; GO:0000467; P:exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IBA:GO_Central.
DR GO; GO:0071044; P:histone mRNA catabolic process; IBA:GO_Central.
DR GO; GO:0071040; P:nuclear polyadenylation-dependent antisense transcript catabolic process; IBA:GO_Central.
DR GO; GO:0071039; P:nuclear polyadenylation-dependent CUT catabolic process; IBA:GO_Central.
DR GO; GO:0071035; P:nuclear polyadenylation-dependent rRNA catabolic process; IBA:GO_Central.
DR GO; GO:0071036; P:nuclear polyadenylation-dependent snoRNA catabolic process; IBA:GO_Central.
DR GO; GO:0071037; P:nuclear polyadenylation-dependent snRNA catabolic process; IBA:GO_Central.
DR GO; GO:0071038; P:nuclear polyadenylation-dependent tRNA catabolic process; IBA:GO_Central.
DR GO; GO:0071051; P:polyadenylation-dependent snoRNA 3'-end processing; IBA:GO_Central.
DR CDD; cd06147; Rrp6p_like_exo; 1.
DR Gene3D; 1.10.150.80; HRDC domain; 1.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR InterPro; IPR002562; 3'-5'_exonuclease_dom.
DR InterPro; IPR012588; Exosome-assoc_fac_Rrp6_N.
DR InterPro; IPR010997; HRDC-like_sf.
DR InterPro; IPR002121; HRDC_dom.
DR InterPro; IPR044876; HRDC_dom_sf.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR036397; RNaseH_sf.
DR InterPro; IPR045092; Rrp6-like.
DR InterPro; IPR049559; Rrp6p-like_exo.
DR PANTHER; PTHR12124:SF47; EXOSOME COMPONENT 10; 1.
DR PANTHER; PTHR12124; POLYMYOSITIS/SCLERODERMA AUTOANTIGEN-RELATED; 1.
DR Pfam; PF01612; DNA_pol_A_exo1; 1.
DR Pfam; PF00570; HRDC; 1.
DR Pfam; PF08066; PMC2NT; 1.
DR SMART; SM00474; 35EXOc; 1.
DR SMART; SM00341; HRDC; 1.
DR SUPFAM; SSF47819; HRDC-like; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR PROSITE; PS50967; HRDC; 1.
PE 3: Inferred from homology;
KW Exosome {ECO:0000256|ARBA:ARBA00022835};
KW Reference proteome {ECO:0000313|Proteomes:UP000007241};
KW rRNA processing {ECO:0000256|ARBA:ARBA00022552}.
FT DOMAIN 469..549
FT /note="HRDC"
FT /evidence="ECO:0000259|PROSITE:PS50967"
FT REGION 707..763
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 779..826
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 826 AA; 92817 MW; 7DD88964A5F3EF7E CRC64;
MGSDNEDFAK KQQDLLSSLA RLTKASQFVN PADVMFLRSS SNSIANSIDA TSNALLSALK
QTTAYARLSA LPSEDDPMHA KKPQLSGEDV IDRFDLIVDV IDDLLEKTDV YLDTLKKTPK
SILESASNTI STNPSGNSTS SFALPKAYGN HRPQLGFQDK IDNSFAPFIP RIQYKPHAKI
PLDLTLVKAP ISSSNLKFQS EDSVDSHENQ LYCVQHPYRS EIETIQYPVV YFKQHPEEIY
RSLESTPLTW IDTPDKLETL CSILEGVTEF AVDLEHHDFR SYQGFTCLMQ ISTRTEDFLV
DTLILRNSLH ALNTSFANPQ IVKVFHGAEM DIQWLQRDFG VYVVDLFDTY HASHALELEG
HSLAFLLKYY CDVVTDKRYQ LADWRIRPLP KEMVHYARMD THYLLYIFDR MRNELLNKSN
PETHNLMHVT LERSGLTSLN TYQKAPYCKD GLSPNGWRSL LNRLKISFNE ENLAVFKAIH
EWRDRIARKE DESLRFVLPN HMLQTLSRVM PTDGPAVVAC CSPTPSLVRL YSKELAHLIF
QTVNTVRQLT TMKNNAAKNI LSQATSESDT AAAPVHIRFD DTVTKQTIYP QTSLAKSDAK
SDNTASNIDL TCPESSTLCP MNTHLQLSCE KRSHGSILVH ATKNSRLFTS KPVDVGNLSS
QSALAIDHAA RIRSRLVLQS PAYTEATPKK PFEPDTPSLK AAVVTATVDS SDPKTDPIES
DAPAPNVDDH TLDIANVDTL TVARSKPNKT NKRQRKSAVE TDDVKQAFTP FDYSVNEASS
ATTHKQSRPQ EVYSPFGEIV TKRNKPIRSR IHRKSGSKSK TFKSSN
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