ID   F4PCY6_BATDJ            Unreviewed;       858 AA.
AC   F4PCY6;
DT   28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT   28-JUN-2011, sequence version 1.
DT   27-MAR-2024, entry version 66.
DE   RecName: Full=Rho-GAP domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=BATDEDRAFT_92106 {ECO:0000313|EMBL:EGF76832.1};
OS   Batrachochytrium dendrobatidis (strain JAM81 / FGSC 10211) (Frog chytrid
OS   fungus).
OC   Eukaryota; Fungi; Fungi incertae sedis; Chytridiomycota;
OC   Chytridiomycota incertae sedis; Chytridiomycetes; Rhizophydiales;
OC   Rhizophydiales incertae sedis; Batrachochytrium.
OX   NCBI_TaxID=684364 {ECO:0000313|EMBL:EGF76832.1, ECO:0000313|Proteomes:UP000007241};
RN   [1] {ECO:0000313|EMBL:EGF76832.1, ECO:0000313|Proteomes:UP000007241}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JAM81 / FGSC 10211 {ECO:0000313|Proteomes:UP000007241};
RG   US DOE Joint Genome Institute (JGI-PGF);
RA   Kuo A., Salamov A., Schmutz J., Lucas S., Pitluck S., Rosenblum E.,
RA   Stajich J., Eisen M., Grigoriev I.V.;
RT   "The draft genome of Batrachochytrium dendrobatidis.";
RL   Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; GL882894; EGF76832.1; -; Genomic_DNA.
DR   RefSeq; XP_006682471.1; XM_006682408.1.
DR   AlphaFoldDB; F4PCY6; -.
DR   STRING; 684364.F4PCY6; -.
DR   GeneID; 18244508; -.
DR   HOGENOM; CLU_333153_0_0_1; -.
DR   InParanoid; F4PCY6; -.
DR   OMA; WSQKQPE; -.
DR   OrthoDB; 1359259at2759; -.
DR   Proteomes; UP000007241; Unassembled WGS sequence.
DR   GO; GO:0032153; C:cell division site; IBA:GO_Central.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   GO; GO:0005096; F:GTPase activator activity; IEA:UniProt.
DR   GO; GO:0007010; P:cytoskeleton organization; IBA:GO_Central.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR   Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR   InterPro; IPR027267; AH/BAR_dom_sf.
DR   InterPro; IPR031160; F_BAR.
DR   InterPro; IPR001060; FCH_dom.
DR   InterPro; IPR008936; Rho_GTPase_activation_prot.
DR   InterPro; IPR000198; RhoGAP_dom.
DR   PANTHER; PTHR23065; PROLINE-SERINE-THREONINE PHOSPHATASE INTERACTING PROTEIN 1; 1.
DR   PANTHER; PTHR23065:SF17; RHO-GTPASE-ACTIVATING PROTEIN RGD2; 1.
DR   Pfam; PF00611; FCH; 1.
DR   Pfam; PF00620; RhoGAP; 1.
DR   SMART; SM00055; FCH; 1.
DR   SMART; SM00324; RhoGAP; 1.
DR   SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR   SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR   PROSITE; PS51741; F_BAR; 1.
DR   PROSITE; PS50238; RHOGAP; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|PROSITE-ProRule:PRU01077};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007241}.
FT   DOMAIN          1..370
FT                   /note="F-BAR"
FT                   /evidence="ECO:0000259|PROSITE:PS51741"
FT   DOMAIN          404..616
FT                   /note="Rho-GAP"
FT                   /evidence="ECO:0000259|PROSITE:PS50238"
FT   REGION          630..669
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        655..669
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   858 AA;  95964 MW;  83D9F0CD1BB16444 CRC64;
     MHFQDWFWGV PDNPILGVSK LHARLVADIV QVEELLSFFQ QRIAAEEYYA NRLADLARKP
     LRPDGFGQDD SLIANIFCTY QQEMHSLSNS HQDVASKISK VLLPLKQFNE DARKICFPKM
     DSIDALAKQY HVALAQVQTL RQLYKQKSIE AAEKTTRFNE SPICGDMPVM EIMINVGLRS
     LTVSEFNDFI AEIQRDVKCT AFYHVKDVGS ILGAYKSCYL GTDMLHYVKT KCRLDENDAL
     AFFNDLHSSG FIRAINGRFA TFVPSLNYQW KRSVYEVTNE VPHRKAIREA EKSEREYKKS
     IMQVETLRQS LDILSAEFMD IIQKILSERI RTIKDVLSTC AETEKIPVHI IRGIQERLFL
     FLETLDADKE TQVLAERDRT GVRPSIPHLF ERYLQGPNDV IFGLDLDVLH SKSGYRVPAI
     LRKSFKFLDD ISETTIEAQS PENSSALSPR KQPHKHLEFW LLPIQNLGSV IALRNELNSG
     KVRAKTLRKY PPSAIIGAIR IYLMELPSSV CSHDLYEPLK LLYLSKSEDV GIMRLNSLRS
     LLATMSSAHF HTLSFLIIRI RSLISDLDPL DSRITDLAIA LGPYFLRPEV ENSVSVHDKH
     RGRLLRDLLV HYDDIISVDI LSTANSAEDL PDGVGMTAKS PNELDSDGDD EEEQQLISPT
     LSSADSEKNR KLSMFSASGS SFKASLIAKR SETRLSIDIQ PKQTNSTPNL MDASRNLNRA
     SAGQDGNGVV GDMFSVAKRV GSSWFTQASD VSQIFIAPSS QPISAVPSVS QLQSTTSTQL
     PGNADLKPLN NDSNTTTDAD VFQTVFSDAL GTDLCTAPKA VSNHSGHSTV KFSDIILSDE
     SDIEVYGKTS NVPTAPFS
//