ID F4RPK3_MELLP Unreviewed; 941 AA.
AC F4RPK3;
DT 28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT 28-JUN-2011, sequence version 1.
DT 13-SEP-2023, entry version 50.
DE RecName: Full=R3H domain-containing protein {ECO:0008006|Google:ProtNLM};
DE Flags: Fragment;
GN ORFNames=MELLADRAFT_48728 {ECO:0000313|EMBL:EGG05547.1};
OS Melampsora larici-populina (strain 98AG31 / pathotype 3-4-7) (Poplar leaf
OS rust fungus).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Pucciniomycotina;
OC Pucciniomycetes; Pucciniales; Melampsoraceae; Melampsora.
OX NCBI_TaxID=747676 {ECO:0000313|Proteomes:UP000001072};
RN [1] {ECO:0000313|Proteomes:UP000001072}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=98AG31 / pathotype 3-4-7 {ECO:0000313|Proteomes:UP000001072};
RX PubMed=21536894; DOI=10.1073/pnas.1019315108;
RA Duplessis S., Cuomo C.A., Lin Y.-C., Aerts A., Tisserant E.,
RA Veneault-Fourrey C., Joly D.L., Hacquard S., Amselem J., Cantarel B.L.,
RA Chiu R., Coutinho P.M., Feau N., Field M., Frey P., Gelhaye E.,
RA Goldberg J., Grabherr M.G., Kodira C.D., Kohler A., Kuees U.,
RA Lindquist E.A., Lucas S.M., Mago R., Mauceli E., Morin E., Murat C.,
RA Pangilinan J.L., Park R., Pearson M., Quesneville H., Rouhier N.,
RA Sakthikumar S., Salamov A.A., Schmutz J., Selles B., Shapiro H.,
RA Tanguay P., Tuskan G.A., Henrissat B., Van de Peer Y., Rouze P.,
RA Ellis J.G., Dodds P.N., Schein J.E., Zhong S., Hamelin R.C.,
RA Grigoriev I.V., Szabo L.J., Martin F.;
RT "Obligate biotrophy features unraveled by the genomic analysis of rust
RT fungi.";
RL Proc. Natl. Acad. Sci. U.S.A. 108:9166-9171(2011).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the NFX1 family.
CC {ECO:0000256|ARBA:ARBA00007269}.
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DR EMBL; GL883112; EGG05547.1; -; Genomic_DNA.
DR RefSeq; XP_007411036.1; XM_007410974.1.
DR AlphaFoldDB; F4RPK3; -.
DR STRING; 747676.F4RPK3; -.
DR EnsemblFungi; EGG05547; EGG05547; MELLADRAFT_48728.
DR GeneID; 18928546; -.
DR KEGG; mlr:MELLADRAFT_48728; -.
DR VEuPathDB; FungiDB:MELLADRAFT_48728; -.
DR eggNOG; KOG1952; Eukaryota.
DR HOGENOM; CLU_005714_3_0_1; -.
DR InParanoid; F4RPK3; -.
DR OrthoDB; 1412at2759; -.
DR Proteomes; UP000001072; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0003676; F:nucleic acid binding; IEA:UniProtKB-UniRule.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd06008; NF-X1-zinc-finger; 4.
DR Gene3D; 3.30.1370.50; R3H-like domain; 1.
DR InterPro; IPR034078; NFX1_fam.
DR InterPro; IPR001374; R3H_dom.
DR InterPro; IPR036867; R3H_dom_sf.
DR InterPro; IPR000967; Znf_NFX1.
DR InterPro; IPR019787; Znf_PHD-finger.
DR PANTHER; PTHR12360; NUCLEAR TRANSCRIPTION FACTOR, X-BOX BINDING 1 NFX1; 1.
DR PANTHER; PTHR12360:SF12; TRANSCRIPTIONAL REPRESSOR NF-X1; 1.
DR Pfam; PF01424; R3H; 1.
DR SMART; SM00393; R3H; 1.
DR SMART; SM00438; ZnF_NFX; 9.
DR SUPFAM; SSF82708; R3H domain; 1.
DR PROSITE; PS51061; R3H; 1.
DR PROSITE; PS50016; ZF_PHD_2; 1.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000001072};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00146}.
FT DOMAIN 194..247
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT DOMAIN 865..929
FT /note="R3H"
FT /evidence="ECO:0000259|PROSITE:PS51061"
FT REGION 1..167
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 92..126
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 143..167
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 941
FT /evidence="ECO:0000313|EMBL:EGG05547.1"
SQ SEQUENCE 941 AA; 103082 MW; FB5F18F39EB459ED CRC64;
MMENQSAVER QVPDSQRGEP IVSNRARGSG RGRGRGQGLP NSHGRLRGHN SGNRLSVRGR
PPSDQSAGAP SEATNTRRHN PARARRARGV NHRSITGSSP NPATSASSDA PRASNEPETS
PPVTSDRGAR PNFRARRQGF GAQLTETAPS GSDGRLQQDA SGDKSNNHIA GSASLSCQDL
SLSARLTLEL STSAYECLIC FSTVSRFQPI YHCKNCFAIF HLRCSSEWAS RSETARGCWR
CPGCQHSHIG QESVPTTYKC WCGKVEHPKR GHHKQEGGGR PKASIPHGCG MSCGKLIAEG
CTHACSLECH PGSCPPCSAV IKTACYCLKT VRTIRCSQLH PIQSHLNPIN DSLLSCEQIC
NRPLSCGLHF CTRTCHAGDC GDCEVTRDKT CYCGRVVKTE QKCTPLIMSE NLLENPRRAC
NTPEGSDFLG EFSCKAPCPW IFGCNIHSCP SVCHPHWPSK LVTCPFSPSV LETCPCGATR
LPIRFTCNDK ITTCSNPCGK RLSACGHACQ QLCHIGPCSG SCKELITTVC RCGKDSIIRP
CCEAVGFRCE RICRVLRHCG KHTCNRTCCP LAFLEGVIKT GKNKKNQSRH QAEEEDPEGL
HQCNLICNRA LSCGLHTCQL RDHKGPCPTC LQANFNEVAC HCGRETLYTF FRATVIQPPV
PCGTIMNCSQ PCRRGPLPCG HPIAPHQCHE APECPPCPFL ANKPCQCDKK SLIRNVRCSQ
RRVTCGQICG NLLSCGAHRC FKLCHPIGEC ETCDQPCGKP RPYCGHGCQI KCHAPSVCSS
EKACQAIIDV RCQCGHIVQK VTCSSNDLRP EGNRDRVLKC NNDCAISQRS FVLASAFVNE
EQTPGKVELG IEWSDELLQF CQQNLVFVKS IENILEEFLN SQPPKISHLF QPQNHFKRKF
TGELAEVYGL SCQCLDEEPR RSVMVNRKPN SKVPQPLLSQ A
//
