ID F4RU81_MELLP Unreviewed; 2938 AA.
AC F4RU81;
DT 28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT 28-JUN-2011, sequence version 1.
DT 08-NOV-2023, entry version 55.
DE SubName: Full=FYVE, beach and WD40-domain-containing protein {ECO:0000313|EMBL:EGG03892.1};
GN ORFNames=MELLADRAFT_89682 {ECO:0000313|EMBL:EGG03892.1};
OS Melampsora larici-populina (strain 98AG31 / pathotype 3-4-7) (Poplar leaf
OS rust fungus).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Pucciniomycotina;
OC Pucciniomycetes; Pucciniales; Melampsoraceae; Melampsora.
OX NCBI_TaxID=747676 {ECO:0000313|Proteomes:UP000001072};
RN [1] {ECO:0000313|Proteomes:UP000001072}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=98AG31 / pathotype 3-4-7 {ECO:0000313|Proteomes:UP000001072};
RX PubMed=21536894; DOI=10.1073/pnas.1019315108;
RA Duplessis S., Cuomo C.A., Lin Y.-C., Aerts A., Tisserant E.,
RA Veneault-Fourrey C., Joly D.L., Hacquard S., Amselem J., Cantarel B.L.,
RA Chiu R., Coutinho P.M., Feau N., Field M., Frey P., Gelhaye E.,
RA Goldberg J., Grabherr M.G., Kodira C.D., Kohler A., Kuees U.,
RA Lindquist E.A., Lucas S.M., Mago R., Mauceli E., Morin E., Murat C.,
RA Pangilinan J.L., Park R., Pearson M., Quesneville H., Rouhier N.,
RA Sakthikumar S., Salamov A.A., Schmutz J., Selles B., Shapiro H.,
RA Tanguay P., Tuskan G.A., Henrissat B., Van de Peer Y., Rouze P.,
RA Ellis J.G., Dodds P.N., Schein J.E., Zhong S., Hamelin R.C.,
RA Grigoriev I.V., Szabo L.J., Martin F.;
RT "Obligate biotrophy features unraveled by the genomic analysis of rust
RT fungi.";
RL Proc. Natl. Acad. Sci. U.S.A. 108:9166-9171(2011).
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DR EMBL; GL883121; EGG03892.1; -; Genomic_DNA.
DR RefSeq; XP_007412685.1; XM_007412623.1.
DR STRING; 747676.F4RU81; -.
DR EnsemblFungi; EGG03892; EGG03892; MELLADRAFT_89682.
DR GeneID; 18935281; -.
DR KEGG; mlr:MELLADRAFT_89682; -.
DR VEuPathDB; FungiDB:MELLADRAFT_89682; -.
DR eggNOG; KOG1786; Eukaryota.
DR HOGENOM; CLU_000175_2_0_1; -.
DR InParanoid; F4RU81; -.
DR OrthoDB; 5478899at2759; -.
DR Proteomes; UP000001072; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR CDD; cd06071; Beach; 1.
DR CDD; cd00065; FYVE_like_SF; 1.
DR CDD; cd01201; PH_BEACH; 1.
DR Gene3D; 1.10.1540.10; BEACH domain; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR InterPro; IPR000409; BEACH_dom.
DR InterPro; IPR036372; BEACH_dom_sf.
DR InterPro; IPR023362; PH-BEACH_dom.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR InterPro; IPR000306; Znf_FYVE.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR PANTHER; PTHR46108; BLUE CHEESE; 1.
DR PANTHER; PTHR46108:SF4; BLUE CHEESE; 1.
DR Pfam; PF02138; Beach; 1.
DR Pfam; PF14844; PH_BEACH; 1.
DR Pfam; PF00400; WD40; 1.
DR SMART; SM01026; Beach; 1.
DR SMART; SM00064; FYVE; 1.
DR SMART; SM00320; WD40; 4.
DR SUPFAM; SSF81837; BEACH domain; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS50197; BEACH; 1.
DR PROSITE; PS51783; PH_BEACH; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 1.
DR PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001072};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT DOMAIN 2121..2254
FT /note="BEACH-type PH"
FT /evidence="ECO:0000259|PROSITE:PS51783"
FT DOMAIN 2265..2562
FT /note="BEACH"
FT /evidence="ECO:0000259|PROSITE:PS50197"
FT REPEAT 2699..2740
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 16..44
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 174..196
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1026..1051
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1195..1215
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2020..2043
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2056..2097
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 16..30
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1027..1051
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2938 AA; 327671 MW; 8F2E8BDA5A99A398 CRC64;
MFSRLRSTSL GHLIELASQR SDSNVTPTSS PNPLAPHPNS APRQRLTDPV FASIAEGRPN
PHPRHSLEAQ FQKHQALERS KSALREAVES LQKIHRDDLS QRRAMLATMA AILSDGVECR
DCMRENGGFL TLVTVLASLI QTDSSQSASY QQTQNLVSDE QLICDSPTPH RLTHAKTSSI
GIGAPPRRSP HLKDLSSSTS SSIATIIGER DAVVELIFKC LALALTGNVT NQQYFSTVIG
YQSVLDAIRI SELLPRDIPT SYASLDQPLD RVNHLRSAYK MFDIIFSFIT ADFTFNDVFT
SVLSTASTSG TRNQMNADEN TGAGFGDDTP TKLREAWGPG KTPLYSTQRD QDDIKYRNMS
SALSLRICQT EVPPRVEIPD AIRLLFALHS DLLFPLTQTW FSDSAWAQAA YELYFLSLKS
IECLASTSRH SQVSLNSAEV IAILLERITT PMSNLASPIA STSKPTGMPH GHQPGLPAGL
EPWPASLILS NRSKNPIDGL GEGERRCRMI IKEILTRLLE IGCSTREARL LFRQMVVSSD
TTESGNETLD DEYLELVLSG MQSSCWPPFI HFDLSRSGSS NVFLQSIGDH PFPPTNGKGW
TFAGWIQVES FDAASGDPLN ILILSDSIHG LIIRVALSNA PHSHHLTVEI YPENIHNQPT
TPRRGVESRS TSYSQSRHIC VKPYLVEFKE FLFRPQRFYH VALVQKPKDK TNMSMISLFI
DGESVGQYPC PWPRSSTSSV SACFGNLPSG RHPDMATSLG QTVCSQCTTG SSGLRPRGTS
TSRWDLAASY LFNQHLSDDM IFVQSTLGPK IFTTWQDALG SFQTYSSSIL RGQDHPPSES
EGSKKVGEQI NDMGQSAQFI DSVVPRDREL STLALSHRRY LNFADSILNA GIPNIRAIDL
PLKNSQHDVS SAASGIALPS SLSHALFQIS GVTLCSPKGL DDSIWKVSGS IFLVKLISLS
STEPQLLSTI KLFFEAISHN WRLSEDAEKI QAYETLAYIL RNKSHLISQE IHRVLLLFAG
IMTEGTPTPK PESQSQRLSP TPENANLDDE TSQVDCGLQE SVITNPLAFR FLLLDFDLWS
RTTLNIQEKH LKSLSYVNER SRWSAFSSKR ISKMNLIPKM LHALRTRQFA LKAERPSVMA
AFIGLLSCVL KVQFNTDSIR GLASYLTASL SPQKLSANST AGTLSTFSFN SPQSVSPDSP
FFDPAQLQDP KSTSSDALQV PQAYIKPMST SITIEEPLMV LEILHNLLLS ANDQESRSYI
SRFLKAINGS KWVLMFFRRN SNPEVILYSY RILIRLIQTQ DIVWIQQFKN VLSGFAILRS
ILTEFSFRNP SILVATLSLI AQVDIRTVPK LKTQDVSLEE MTSVIQSIEG VPSEIIAREM
LPVVLALLKP VYVVKQDLTS APALYVLEWL RVQSQNDRWN EIIGHEDMVQ LWGPYVTMLA
SLANQDNVVV DFDEYHGEMS SASNTSASDY SCLRSFPLNI TSMSSSDGDQ FNQVIIDEPR
ALVVIVDEPG KISSPSLTVY SNMPTSTVPV SVPRRQMTRA NKPHLNPKII IPQTITINGE
AISLPPSPDG LYQGDQFANN LHDMVRESRF PKIHTTDDET DPRSITLSSW ENIDPEVGNQ
LGSLAKQLII YHVFQHVVIH QPLPPSHDDE FVSSVLTDKR LRLDRLERLL NLVVTSNGLE
QQKAAWITPL FDDVVSMAIS ETDSSTLPLN WLIPTLAHGY IAGWLQPTGR ILSDLITFVV
DTTKSDSVPW LSSRTLQGAE ILLEQLSSHR LAGLVKIAPE LASRLVYLMT QYISGSTELC
ALACDVLKST CDCMPMCFDE LQLDLDDWEN EMPKSDPGSV ENCKETGSFK IDQDPGSIFV
KFLQMTVEDI TTIVRNQASK NLAGKLDWIQ FATELEVKGN VYQAKSQSIS NQMWTEYRNK
TTIESRKLDA ATAKMHTWAK RVRELDSSRY ADIRQDNHEI KQYLEIQLSK RISELYRPFA
VLGKSSNNTP SYWFLDTTEG PSRQRRKLRR VPIKMDTHIV QQRKTRHHRV RSLGTSRRDS
YQDLPDSHKL VETMISDVQS PSSPTSATMT EHDTWNENDG LTASPPEGLS SLGSTSATEG
VKELSVDFAE DRSRRILKSL EPGDVIQAVW NVEQVIGLDT CPGLFLIAKN NIYIIDGFIQ
TSKGELVNSW QSEAWEERDP HLRMMATLSR QTAKLNSRAA AHQSRRWSYT DIVALSSRKW
LFRDICIEFV FADGRSRLLT FSGNKRDEAM KRLRDCIAKS TGSEHLYKRE SNLKSQTELW
QSGQLSNHGY LLYLNDAAGR TYRDLTQHPV FPWILADYRS ETLDLKNPTT FRKLALPMGA
QTEARKRDFI ERYTSLEEFG AIGDDKMKPA HYMTHYSSAV VVCGFMIRLQ PFCDHFLEIQ
GSFDHADRTF WSMERAWLSA SEQSRSDVRE LTPEFFHCPE FLKNINNFNL GSRQEGGTPI
DDVELPPWAH RDPRLFVELH REALESDYVS ENLHHWIDLI FGFKQRGQAA LESINVFQEC
SYEGSVSLDN IHDESERSSV VGAMCNWGLT PSQIFSVPHP PRGKQAKHAF DSKSVINSST
CSALVQSIVP LQSIGQPISH IYPAQMLEKT TVSGLRSLLV PPNGSHRLDW GFLDQSLRIF
DSSGAVCATF EGITSEEISA ACFADHRTLA TASTDSTISL WRFTWRLTGR PHLQQVEVLR
GHSAPITCLV TSRVMSIILS GCADGLAMIW DLNRALLVRS LPHPTPVTVA AISDSTGDIA
TCSELTVRIW SVNGDLLSTL TVSQHHADFI TACAWSTAEV KPLLITGHRS GKIMMWQRKS
AHAESLSKPW KMDLIHVFQQ ESGCSVTALA LSNRVMLVGD ALGRLFPWAL PGSAVPIPDA
VSSICMVCDH KFGILEGRRR CLACAAIICS SCQDCLPGSV RCCVVCVARL TNYQEPKQ
//
