ID F4RZG4_MELLP Unreviewed; 728 AA.
AC F4RZG4;
DT 28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT 28-JUN-2011, sequence version 1.
DT 27-MAR-2024, entry version 67.
DE RecName: Full=Histone-lysine N-methyltransferase {ECO:0008006|Google:ProtNLM};
GN ORFNames=MELLADRAFT_66502 {ECO:0000313|EMBL:EGG02258.1};
OS Melampsora larici-populina (strain 98AG31 / pathotype 3-4-7) (Poplar leaf
OS rust fungus).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Pucciniomycotina;
OC Pucciniomycetes; Pucciniales; Melampsoraceae; Melampsora.
OX NCBI_TaxID=747676 {ECO:0000313|Proteomes:UP000001072};
RN [1] {ECO:0000313|Proteomes:UP000001072}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=98AG31 / pathotype 3-4-7 {ECO:0000313|Proteomes:UP000001072};
RX PubMed=21536894; DOI=10.1073/pnas.1019315108;
RA Duplessis S., Cuomo C.A., Lin Y.-C., Aerts A., Tisserant E.,
RA Veneault-Fourrey C., Joly D.L., Hacquard S., Amselem J., Cantarel B.L.,
RA Chiu R., Coutinho P.M., Feau N., Field M., Frey P., Gelhaye E.,
RA Goldberg J., Grabherr M.G., Kodira C.D., Kohler A., Kuees U.,
RA Lindquist E.A., Lucas S.M., Mago R., Mauceli E., Morin E., Murat C.,
RA Pangilinan J.L., Park R., Pearson M., Quesneville H., Rouhier N.,
RA Sakthikumar S., Salamov A.A., Schmutz J., Selles B., Shapiro H.,
RA Tanguay P., Tuskan G.A., Henrissat B., Van de Peer Y., Rouze P.,
RA Ellis J.G., Dodds P.N., Schein J.E., Zhong S., Hamelin R.C.,
RA Grigoriev I.V., Szabo L.J., Martin F.;
RT "Obligate biotrophy features unraveled by the genomic analysis of rust
RT fungi.";
RL Proc. Natl. Acad. Sci. U.S.A. 108:9166-9171(2011).
CC -!- SUBCELLULAR LOCATION: Chromosome {ECO:0000256|ARBA:ARBA00004286}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; GL883132; EGG02258.1; -; Genomic_DNA.
DR RefSeq; XP_007414515.1; XM_007414453.1.
DR AlphaFoldDB; F4RZG4; -.
DR STRING; 747676.F4RZG4; -.
DR EnsemblFungi; EGG02258; EGG02258; MELLADRAFT_66502.
DR GeneID; 18930639; -.
DR KEGG; mlr:MELLADRAFT_66502; -.
DR VEuPathDB; FungiDB:MELLADRAFT_66502; -.
DR eggNOG; KOG1083; Eukaryota.
DR HOGENOM; CLU_380384_0_0_1; -.
DR InParanoid; F4RZG4; -.
DR OrthoDB; 950362at2759; -.
DR Proteomes; UP000001072; Unassembled WGS sequence.
DR GO; GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0042054; F:histone methyltransferase activity; IEA:InterPro.
DR Gene3D; 2.170.270.10; SET domain; 1.
DR InterPro; IPR006560; AWS_dom.
DR InterPro; IPR003616; Post-SET_dom.
DR InterPro; IPR001214; SET_dom.
DR InterPro; IPR046341; SET_dom_sf.
DR PANTHER; PTHR22884:SF413; HISTONE-LYSINE N-METHYLTRANSFERASE CG1716-RELATED; 1.
DR PANTHER; PTHR22884; SET DOMAIN PROTEINS; 1.
DR Pfam; PF17907; AWS; 1.
DR Pfam; PF00856; SET; 1.
DR SMART; SM00317; SET; 1.
DR SUPFAM; SSF82199; SET domain; 1.
DR PROSITE; PS51215; AWS; 1.
DR PROSITE; PS50868; POST_SET; 1.
DR PROSITE; PS50280; SET; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001072};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 484..529
FT /note="AWS"
FT /evidence="ECO:0000259|PROSITE:PS51215"
FT DOMAIN 541..660
FT /note="SET"
FT /evidence="ECO:0000259|PROSITE:PS50280"
FT DOMAIN 697..713
FT /note="Post-SET"
FT /evidence="ECO:0000259|PROSITE:PS50868"
FT REGION 1..54
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 75..240
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 343..461
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 675..694
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 83..215
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 343..376
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 425..441
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 728 AA; 81021 MW; 316F5F5F34A252D3 CRC64;
MWRPGRWIYV DQDGGNDQEQ EQSTKSAPAD HSSHRRSCPF DPASPPWKTA GQVPIETAVF
KDGRRMSKRF EKLLKEKQDK TKTSTTNAAS NSTITTRKER SKSVISNNSV SIGNKEPQYP
PTRRSRKSSS VTSNQIINQN SQTTSSALDE PSKPSSSTLK TSPPVSCEVL NASHKPSSPS
TSLVNPISPT STLQEPTTLS VPPSNAHQVL SSPPLLSVPE SDELGVAQST RTSIRVDNHH
HTATENQELI NTQLGDPVAV EPSASSSHPP QIALSIIPTK RFRPWEALKG IQTDGAEVAG
DLKLIQEGTQ SKLTRYHHNH RKRDAPSATF TSDLSLMQPA PDHVSFQRNA SPGAPSSTTK
HYSDHSSDLT ELSSSLTDLS DEDDHCPQSS SAYSESELED ECLPNSLVRT VRRPTSTARA
SNKPRPPKLK IHRRHRRRRI SRPDASTQML DDEEEDEDEQ RLPPPYVKIK SNVYSYRKPE
VSDLPPAICG CTDGGCGEKC LNRVTSYLCD PKRCSLGQSC TNIPLNLRKD LIDESTQKLG
KGLKVFYTGD QRGWGLKTEI RLKAGIFLID YRGEIISRES CYKRVVNDYR GMSSFYFLDY
DGSDVIDAGK KGNCSRFINH SCEPNLRVER FKLSGLEEYQ IGLFTLRDIE IDEELSYNYG
WQNFSDIAPT SNIRTSHKES DAANEDQEEM TTATAPTIQR CHCGSKVCKG FLGPKKKEDS
RRKGRVDE
//
