ID F4S6X1_MELLP Unreviewed; 424 AA.
AC F4S6X1;
DT 28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT 28-JUN-2011, sequence version 1.
DT 24-JAN-2024, entry version 55.
DE RecName: Full=RING-Gid-type domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=MELLADRAFT_45698 {ECO:0000313|EMBL:EGF99650.1};
OS Melampsora larici-populina (strain 98AG31 / pathotype 3-4-7) (Poplar leaf
OS rust fungus).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Pucciniomycotina;
OC Pucciniomycetes; Pucciniales; Melampsoraceae; Melampsora.
OX NCBI_TaxID=747676 {ECO:0000313|Proteomes:UP000001072};
RN [1] {ECO:0000313|Proteomes:UP000001072}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=98AG31 / pathotype 3-4-7 {ECO:0000313|Proteomes:UP000001072};
RX PubMed=21536894; DOI=10.1073/pnas.1019315108;
RA Duplessis S., Cuomo C.A., Lin Y.-C., Aerts A., Tisserant E.,
RA Veneault-Fourrey C., Joly D.L., Hacquard S., Amselem J., Cantarel B.L.,
RA Chiu R., Coutinho P.M., Feau N., Field M., Frey P., Gelhaye E.,
RA Goldberg J., Grabherr M.G., Kodira C.D., Kohler A., Kuees U.,
RA Lindquist E.A., Lucas S.M., Mago R., Mauceli E., Morin E., Murat C.,
RA Pangilinan J.L., Park R., Pearson M., Quesneville H., Rouhier N.,
RA Sakthikumar S., Salamov A.A., Schmutz J., Selles B., Shapiro H.,
RA Tanguay P., Tuskan G.A., Henrissat B., Van de Peer Y., Rouze P.,
RA Ellis J.G., Dodds P.N., Schein J.E., Zhong S., Hamelin R.C.,
RA Grigoriev I.V., Szabo L.J., Martin F.;
RT "Obligate biotrophy features unraveled by the genomic analysis of rust
RT fungi.";
RL Proc. Natl. Acad. Sci. U.S.A. 108:9166-9171(2011).
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DR EMBL; GL883156; EGF99650.1; -; Genomic_DNA.
DR RefSeq; XP_007417054.1; XM_007416992.1.
DR AlphaFoldDB; F4S6X1; -.
DR STRING; 747676.F4S6X1; -.
DR EnsemblFungi; EGF99650; EGF99650; MELLADRAFT_45698.
DR GeneID; 18928265; -.
DR KEGG; mlr:MELLADRAFT_45698; -.
DR VEuPathDB; FungiDB:MELLADRAFT_45698; -.
DR eggNOG; KOG2817; Eukaryota.
DR HOGENOM; CLU_020227_4_0_1; -.
DR InParanoid; F4S6X1; -.
DR OrthoDB; 208500at2759; -.
DR Proteomes; UP000001072; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0061630; F:ubiquitin protein ligase activity; IEA:InterPro.
DR GO; GO:0045721; P:negative regulation of gluconeogenesis; IEA:UniProt.
DR GO; GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; IEA:InterPro.
DR CDD; cd16652; dRING_Rmd5p-like; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR024964; CTLH/CRA.
DR InterPro; IPR006595; CTLH_C.
DR InterPro; IPR045098; Fyv10_fam.
DR InterPro; IPR006594; LisH.
DR InterPro; IPR037683; Rmd5_dRing.
DR InterPro; IPR044063; ZF_RING_GID.
DR InterPro; IPR027370; Znf-RING_euk.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR12170:SF3; GH10162P; 1.
DR PANTHER; PTHR12170; MACROPHAGE ERYTHROBLAST ATTACHER-RELATED; 1.
DR Pfam; PF10607; CTLH; 1.
DR Pfam; PF13445; zf-RING_UBOX; 1.
DR SMART; SM00668; CTLH; 1.
DR SMART; SM00667; LisH; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50897; CTLH; 1.
DR PROSITE; PS50896; LISH; 1.
DR PROSITE; PS51867; ZF_RING_GID; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000001072};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU01215}.
FT DOMAIN 162..219
FT /note="CTLH"
FT /evidence="ECO:0000259|PROSITE:PS50897"
FT DOMAIN 368..410
FT /note="RING-Gid-type"
FT /evidence="ECO:0000259|PROSITE:PS51867"
FT ZN_FING 368..410
FT /note="RING-Gid-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01215"
SQ SEQUENCE 424 AA; 48025 MW; 3C7617F0DA106A3C CRC64;
MQFMKRDWEK LSNKASTNQS ELISNLDQLI SHLELLRENN GNLEHTQTEL ESILSQSKLI
SKSALQSHKE YHSLCSKWQK MIDKRFSQTV LPLLGTQATL NSDPSLSAND DPKLKRPFES
YSARSALDRV IANHLIRQGR FETAKILLKE CGHSIPKEHI ASCESLYQIL DCIRSGDLAP
AIQWAEEHRE WLEERGSPLA FDLRRSEFVH LLTDDDLKVK EEANGFNSIN AQQRALAYAS
EHFRRFISTR WDEAVKLTSS VLYAPLSNLR KSPYSEFYQS AQTGSLVPWV HAHHLIPLFT
QEFYAALRWS KELPLVVATD LGSGGALAKI AKVRSVMKEK RTEWSQADEL PVEIPLPAEY
RFHSVFACPV SKEQSTEINP PMMMPCGHVI AQESMKKLAK GGGTVKCPYC PSSASMTTAM
EVYF
//
