ID F4W633_ACREC Unreviewed; 427 AA.
AC F4W633;
DT 28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT 28-JUN-2011, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE RecName: Full=26S proteasome regulatory subunit 8 {ECO:0000256|ARBA:ARBA00040909};
GN ORFNames=G5I_00926 {ECO:0000313|EMBL:EGI70168.1};
OS Acromyrmex echinatior (Panamanian leafcutter ant) (Acromyrmex octospinosus
OS echinatior).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC Formicidae; Myrmicinae; Acromyrmex.
OX NCBI_TaxID=103372 {ECO:0000313|Proteomes:UP000007755};
RN [1] {ECO:0000313|EMBL:EGI70168.1}
RP NUCLEOTIDE SEQUENCE.
RA Nygaard S., Zhang G.;
RT "The genome of the leaf-cutting ant Acromyrmex echinatior suggests key
RT adaptations to social evolution and fungus farming.";
RL Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the AAA ATPase family.
CC {ECO:0000256|ARBA:ARBA00006914, ECO:0000256|RuleBase:RU003651}.
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DR EMBL; GL887707; EGI70168.1; -; Genomic_DNA.
DR AlphaFoldDB; F4W633; -.
DR STRING; 103372.F4W633; -.
DR EnsemblMetazoa; XM_011061620.1; XP_011059922.1; LOC105149303.
DR eggNOG; KOG0728; Eukaryota.
DR InParanoid; F4W633; -.
DR Proteomes; UP000007755; Unassembled WGS sequence.
DR GO; GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0008233; F:peptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd19502; RecA-like_PAN_like; 1.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR041569; AAA_lid_3.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR003960; ATPase_AAA_CS.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR032501; Prot_ATP_ID_OB_2nd.
DR PANTHER; PTHR23073; 26S PROTEASOME REGULATORY SUBUNIT; 1.
DR PANTHER; PTHR23073:SF166; 26S PROTEASOME REGULATORY SUBUNIT 8; 1.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF17862; AAA_lid_3; 1.
DR Pfam; PF16450; Prot_ATP_ID_OB_C; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00674; AAA; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|RuleBase:RU003651};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Hydrolase {ECO:0000313|EMBL:EGI70168.1};
KW Nucleotide-binding {ECO:0000256|RuleBase:RU003651};
KW Protease {ECO:0000313|EMBL:EGI70168.1};
KW Proteasome {ECO:0000256|ARBA:ARBA00022942};
KW Reference proteome {ECO:0000313|Proteomes:UP000007755}.
FT DOMAIN 203..342
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT COILED 49..90
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 427 AA; 48232 MW; 53367C515E29E41A CRC64;
MHYVLRVKPV LHQLQADCKF VATANLKLMD IDEKNAKGEG FKPYYITKIE ELQLIVAEKS
QNLRRLQAQR NELNAKVRML REELQLLQEQ GSYVGEVVKP MDKKKVLVKV HPEGKFVVDI
DKNIDINDVT PNSRVALRNE SYTLHKILPN KVDPLVSLMM VEKVPDSTYE MVGGLDKQIK
EIKEVIELPV KHPELFDALG IAQPKGVLLY GPPGTGKTLL ARAVAHHTEC TFIRVSGSEL
VQKFIGEGSR MVRELFVMAR EHAPSIIFMD EIDSIGSSRI ESGSGGDSEV QRTMLELLNQ
LDGFEATKNI KVIMATNRID ILDPALLRPG RIDRKIEFPP PNEEARLDIL KIHSRKMNLT
RGINLRKIAE LMPGASGAEV KGVCTEAGMY ALRERRVHVT QEDFEMAVAK VMQKDSEKNM
SIKKLWK
//
